IEEE Instrumentation and Measurement Technology Conference 20 16 (is always abbreviated as IEEE 12MTC 2016 or12MTC 2016) is the flagship conference of IEEE Instrumentation and Measurement Society. In 2016, the Conference attracts more than 235 attendees from 41 countries/areas. There were 1 plenary talk, 2 keynotes, 16 tutorials and 294 papers presented during the Conference. 12MTC 2016 included new technical activities, the industry sessions, special talks which highlighted the issues of paper preparation for submission, and a special invited talk session. All the key events and the hot topics revealed by this conference would be reported and highlighted in this report.