The trajectory of an orbiting spacecraft is determined from an orbit determination program. Two inputs to this program, among others, are the range and range rate relative to some known location. The arithmetic and measurement errors in the determinations of the range, range rate, and range differences were identified and evaluated. These uncertainties are tabulated for one way and two way systems. A comparison of the measurement error contributions illustrate the predominance of thermal noise effects under low power budget conditions, with the other error sources becoming relevent for the high power budget case. The evaluated uncertainties are summarized as root sum squared noise and bias errors.