We identify two catagories of probe-orbiter interactions which benefit the science return from a particular mission. The first category is termed "Mission Design Aspects". This category is meant to describe those aspects of the mission design involving the orbiter that affect the science return from the probe(s). The second category of probe-orbiter interaction is termed "Orbiter-Probe Science Interactions", and is meant to include interactions between oribter and probe(s) that directly involve science measurements made from each platform. Two mission related aspects of probe-orbiter interactions are delivery of a probe(s) to the entry site(s) by an orbiter, and communication between each probe and the orbiter. We consider four general probe-orbiter science interactions that greatly enhance, or in certain cases are essential for, the mission science return. The four topics are, global context of the probe entry site(s), ground truth for remote sensing observations of an orbiter, atmospheric composition measurements, and wind measurements.