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The central hypothesis for the proposed research is that a collaborative translational autism research program with the military will result in the improved diagnosis and care of those enrolled in the study and enhance biomedical research on the diagnosis, causes, and treatment of autism spectrum disorders (ASD), in general. With approved revised Specific Aims, during this project, we enrolled 65 families (259 individuals) in the existing Central Ohio Registry for Autism, including 26 families...
Topics: DTIC Archive, NATIONWIDE CHILDREN'S HOSPITAL COLUMBUS OH RESEARCH INST, *MENTAL DISORDERS,...
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Source: http://www.documentcloud.org/documents/5784918-ADA995289-pdf.html
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Source: http://www.documentcloud.org/documents/6190733-FOIA-2019-147.html
Obesity, which induces low-grade inflammation, is a known risk factor for worse prognosis in many cancers including breast. We found that sphingosine-1-phosphate (S1P) produced by sphingosine kinases (SphKs) plays a critical role in obesity-related inflammation and breast cancer. Obesity increased S1P in the tumor microenvironment, as well as in the primary tumors. FTY720, a functional antagonist of S1PR1, dramatically decreased cancer progression by reducing expressions of SphK1 and S1PR1, and...
Topics: DTIC Archive, VIRGINIA COMMONWEALTH UNIV RICHMOND, *BREAST CANCER, *OBESITY, CELLS(BIOLOGY),...
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Meeting the Soldier-centered intent of the Army Learning Model (ALM) has many challenges, including conducting assessments. Without effective assessment methodologies, instructors will not be able to provide students with tailored learning experiences. This research describes the development of a prototype, proof-of-concept measurement and assessment system for the Army Reconnaissance Course (ARC) to meet assessment challenges. The ARC, with a focus on the development of leader attributes, is...
Topics: DTIC Archive, Ratwani, Krista L, Aptima Woburn United States, army personnel, instructors,...
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The current Zika virus outbreak has galvanized the public health community, resulting in rapid action by entities ranging from the World Health Organization to the United States government. The rapid response to Zika is perhaps the first of its kind, and it undoubtedly has been made possible by the lessons learned from the response to the 2014 Ebola virus outbreak in West Africa. However, Zika virus is not Ebola virus. As of February 2016 there were only 296 publications on Zika in the PubMed...
Topics: DTIC Archive, Martins, Karen, USAMRIID Frederick United States, vaccines, VIRUS DISEASES,...
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Gold nanoclusters (AuNCs) synthesized intracellularly have potential for use as in-vivo or in-vitro pressure probes for evaluating the effects of traumatic brain injury. AuNCs were grown within NG-108-15 neuroblastoma-glioma hybrid cells, indicated by increased fluorescence intensity at 488 nm. Effect of gold salt concentration on fluorescence intensity was evaluated. Cell viability at 24-h postgold salt addition was tested via an MTS cell viability assay.
Topics: DTIC Archive, Gillan, Maggie, US Army Research Laboratory Aberdeen Proving Ground United States,...
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We conducted an autonomous survey of sea-ice thickness using the Polar rover Yeti to tow an electromagnetic induction meter over sea ice in McMurdo Sound, Antarctica. This proof-of-concept survey aimed to demonstrate improved efficiency relative to manual surveys routinely conducted to assess the safety of roads and runways constructed on the sea ice. Yeti executed the autonomous survey on 11 November 2014. This report describes the methods used, compares the measured ice-thickness profiles...
Topics: DTIC Archive, Lever,James H, ENGINEER RESEARCH AND DEVELOPMENT CENTER HANOVER NH HANOVER United...
The acquisition and installation of the nanosecond flash photolysis spectrometer have been completed. The instrument is used to enhance both research and teaching at Spelman College. This acquisition includes: (1) LP980 laser flash photolysis instrument (EdinburghInstruments), (2) Nd:YAG laser, (3) cuvette holder (-40 110 degrees C), and (4) laser table. The laser system generates 532, 355, and 266 nm wavelengths. The current setup also includes: (1) an iCCD (intensified charge-coupled device)...
Topics: DTIC Archive, Jeilani,Yassin A, SPELMAN COLL ATLANTA GA ATLANTA United States, physical chemistry,...
The Double Column GRC Dynatup 8200 Drop-Weight pneumatic rebound brake system was intended to prevent secondary tup impacts on test specimen after the initial strike. Our investigation lead to the discovery of multiple impacts from a single test. To achieve a single mass impact of energy on laminate material test panel, we successfully modified the braking system. The details of which are explained in this report.
Topics: DTIC Archive, Gray, David, Weapons and Materials Research Directorate, US Army Research Laboratory...
Army missions take place in dynamic environments, where changing illumination, precipitation, and vegetation can modify saliency and context of an outdoor scene, obscure features, and degrade object recognition. For Army missions, scene understanding tools need to account for dynamic environments that change as a function of space and time and should be tested in mission simulating conditions. In addition, the impact of dynamic environments should be included in the scene understanding...
Topics: DTIC Archive, Tunick, Arnold, US Army Research Laboratory Adelphi United States, computer vision,...
This project aims to (i) control graphene electronic structure by perturbing it using nanoparticles; (ii) fabricate graphene field-effect transistors and demonstrate their superior performances; (iii) investigate the THz and sub-THz characteristics of graphene layers. We have demonstrated engineering the bandgap of single layer Graphene by decorating with randomly distributed zinc oxide (ZnO) and gold nanoparticles. The proximity of nanoparticles and Graphene break Graphenes sublattice symmetry...
Topics: DTIC Archive, Pala,Nezih, Florida International University Miami United States, FIELD EFFECT...
Topics: DTIC Archive, McClean, Julie L, UNIVERSITY OF CALIFORNIA, SAN DIEGO LA JOLLA, United States
Non-compressible torso hemorrhage remains the leading cause of preventable death on the battlefield and a leading cause of death in civilian centers. The purpose of this project is to provide basic morphometric understanding of aortic and vena caval anatomy as it relates to the rest of the body with the goal of enabling the use of various occlusion catheters that can control bleeding in non-compressible torso injuries in the field. One year into the project, we have identified and processed the...
Topics: DTIC Archive, Wang,Stewart C, University of Michigan Ann Arbor United States, trauma, ABDOMEN,...
The assembly of individual protein subunits into large-scale symmetrical structures is widespread in nature and confers new biological properties. Engineered protein assemblies have potential applications in nanotechnology and medicine; however, a major challenge in engineering assemblies de novo has been to design interactions between the protein subunits so that they specifically assemble into the desired structure. Here we demonstrate a simple, generalizable approach to assemble proteins...
Topics: DTIC Archive, Sciore,Aaron, MICHIGAN UNIV ANN ARBOR ANN ARBOR United States, mass spectrometry,...
Aquatic habitats are among the most imperiled habitats on dryland military installations, yet they harbor a disproportionately high amount of biodiversity given the small land area they cover. Aquatic invertebrates (insects and allied taxa) constitute a major part of this biodiversity and form a critical part of the food web that sustains aquatic, riparian, and terrestrial organisms, including Federally Threatened or Endangered species. Biodiversity in dryland aquatic habitats is strongly...
Topics: DTIC Archive, Lytle,David A, University of Washington Seattle United States, aquatic organisms,...
This literature review surveys and analyses the existing literature, policy and practice in order to support Headquarters Joint Operations Commands comprehensive incorporation of United Nations Security Council Resolution 1325 into Australian Defence Force (ADF) operational planning and conduct. It draws upon academic literature as well as practitioner reports on military implementation of the Women, Peace and Security agenda. The literature review will enhance understanding of good practice...
Topics: DTIC Archive, Hutchinson,Susan, Defence Science and Technology Group Fishermans Bend Victoria...
This report describes the development, testing, and finite element model (FEM) of the Warrior Injury Assessment Manikin (WIAMan) Anthropomorphic Test Device (ATD) Lumbar Spine Materials Demonstrator. A primary objective of this work was to generate experimental data for FEM validation and to create lumbar spine demonstrators that were used to characterize candidate materials to assess the effect of material type and hardness for the lumbar spine ATD component. Several rubber chemistries and...
Topics: DTIC Archive, Gibson,Michael W, US Army Research Laboratory Aberdeen Proving Ground United States,...
Space and Naval Warfare Systems Center Pacific (SSC Pacific) performed the studies described in this report to develop a new National Pollutant Discharge Elimination Systems (NPDES) Permit for the discharge of effluents from the Apra Harbor Wastewater Treatment Plant (WWTP) in Agat, Guam, into Tipalao Bay of the Philippine Sea. The technical approach adhered to proposed U.S. Environmental Protection Agency (USEPA) guidelines to develop and apply mixing zone analysis, recalculation procedure,...
Topics: DTIC Archive, Earley,Patrick J, Space and Naval Warfare Systems Center Pacific San Diego United...
The noctuid moths, Archanara geminipuncta and A. neurica, were selected as the most promising candidates for biological control of common reed. Successful larval development was only found on Phragmites spp., but development was also possible on the native North American subspecies P. australis subsp. americanus. However, open-field oviposition tests showed a strong preference of females for both European and introduced P. australis. Because of the higher egg mortality on native reed, the...
Topics: DTIC Archive, Haefliger,Patrick, Centre for Agriculture and Bioscience International (CABI)...
Defense Technical Information Archive
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The continued rise of self-radicalized lone-wolf terrorist attacks and mass shootings by mentally unstable individuals presents significant security challenges for military personnel serving outside of DoD facilities and at geographically separated units that offer no security. The recent attack on a recruiting center in Chattanooga, TN highlights this concern and raises the question of whether arming additional military members is a prudent force protection measure to counter this emerging...
Topics: DTIC Archive, Bowman,John K, Aiar War College Maxwell Air Force Base United States, reserve officer...
Harvested ferroelectric nanoparticles of BaTiO3 and LiNbO3 were dispersed in Ferroelectric Liquid Crystals (FLCs) with very high spontaneous polarization (Ps). The electrooptic and dielectric parameters were documented. The dipoles of ferroelectric nanoparticles and those of FLCs are partially cancelled in an antiparallel manner. The role of cell parameters like thickness of the Nylon 6 polymer layer and the change in preparation of the polymer layer due to different mechanical rubbing cycles...
Topics: DTIC Archive, Shukla,R K, Technische Universitt Darmstadt Darmstadt Germany, liquid crystals,...
The use of UAVs to preform targeted strikes on enemy personnel has changed the viewpoint of the American populace towards the military; in turn, causing change in how politicians choose to present their arguments for or against military campaigns. This research will analyze data from various sources in reference to the American approval rating for UAV targeted strikes. In addition, foreign policy, legislation, legal analysis, and exploration of moral and ethical consequences will be reviewed to...
Topics: DTIC Archive, Johnson,Gregory D, AIR COMMAND AND STAFF COLLEGE, AIR UNIVERSITY MAXWELL AFB United...
This research paper uses a problem/solution framework to identify how Air Force Space Command (AFSPC) can integrate and improve cybersecurity for legacy and modern weapon systems to reduce the cybersecurity attack-surface. With Department of Defense (DOD) networks and mission systems undergoing nearly 250,000 attacks a day, AFSPC must take immediate action to thwart the attacks from adversarial nation states and non-state actors alike. While there are numerous cybersecurity concerns, or...
Topics: DTIC Archive, Noonan,Timothy P, AIR COMMAND AND STAFF COLL MAXWELL AFB AL MAXWELL AFB United...
There are significant cybersecurity challenges confronting the Department of Defense (DoD) and other U.S. departments and agencies due to their reliance on globalized information technology (IT) marketplace with insufficient security measures in place for a cyber supply chain providing vital IT products destined for mission critical systems. An unsecured globalized cyber supply chain provides amply opportunity for malicious actors to compromise, corrupt, and introduce counterfeit cyber...
Topics: DTIC Archive, Van Etten,Stephen R, AIR COMMAND AND STAFF, AIR UNIVERSITY MAXWELL AFB United States,...
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The goal of the current study was to determine if computational fluid dynamics is capable of accurately predicting the forces and moments on the F/A-18E Super Hornet while performing several complicated maneuvers. Past F/A-18E computational studies have mainly focused on static wind-tunnel scale calculations with the results being compared to existing wind-tunnel data. In recent years, some pitching calculations were conducted at wind-tunnel scale to increase the throughput of the computational...
Topics: DTIC Archive, Green, Bradford E, Naval Air Warfare Center Aircraft Division Patuxent River United...
A stochastic process statistical complexity stands out as a fundamental property: the minimum information required to synchronize one process generator to another. How much information is required, though, when synchronizing over a quantum channel? Recent work demonstrated that representing causal similarity as quantum state-indistinguishability provides a quantum advantage. We generalize this to synchronization and offer a sequence of constructions that exploit extended causal structures,...
Topics: DTIC Archive, Mahoney,John R, CALIFORNIA UNIV DAVIS DAVIS United States, stochastic processes,...
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We find an optical Raman lattice without spin-orbit coupling showing chiral topological orders for cold atoms. Two incident plane-wave lasers are applied to simultaneously generate a double-well square lattice and periodic Raman couplings, the latter of which drive the nearest-neighbor hopping and create a staggered flux pattern across the lattice. Such a minimal setup can yield the quantum anomalous Hall effect with a large gap-bandwidth ratio in the single particle regime, while in the...
Topics: DTIC Archive, Liu, Xiong-Jun, PEKING UNIV BEIJING (CHINA) BEIJING China, optical lattices, atoms,...
The convergence of popular wars, ethnic and religious conflict, ideological extremism, and competition over diminishing resources are messy scenarios that defy prescriptive solutions. Yet this messiness is what increasingly defines todays operating environment, requiring adaptive combinations of knowledge and action within a unified interagency framework. In this context, Special Operations Forces (SOF), to include Information Operations and Civil Affairs,plays an increasingly active and...
Topics: DTIC Archive, Varhola, Christopher, Joint Special Operations University Senior Fellow MacDill AFB...
A breathing apparatus with a partial failure may have higher breathing resistance (R) than expected or a breathing apparatus may be needed for harder work than it was designed for. The effects of very high R on physical endurance and on breathing was not known. Fifteen subjects took part in this IRB approved study to determine such effects during moderate exercise (60 of peak O2 consumption) on a cycle ergometer on dry land at sea level. R was such that the work of breathing per volume...
Topics: DTIC Archive, Warkander,Dan, Navy Experimental Diving Unit Panama City United States, BREATHING...
We established cellular models in MDA-MB-231 and immortalized primary epithelial cells to study the effect of KHDRBS3 and SRSF12 on tumor progression and metastasis (Task1). We analyzed the effect of KHDRBS3 depletion on the growth and migration properties of the MDABD-231 cells in vitro (Task 1) and their ability to form tumors and metastasize in mouse xenograft models (Task 2). The results of similar experiments for SRPK1 were recently published and demonstrated a role for SRPK1 in migration...
Topics: DTIC Archive, Stoilov, Peter, WEST VIRGINIA UNIV RESEARCH CORP MORGANTOWN MORGANTOWN United States,...
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Traditional insider threat practices involve negative incentives that attempt to force employees to act in the interests of the organization and, when relied on excessively, can result in negative unintended consequences that exacerbate insider threats. Positive incentives that attempt to encourage employees to act in the interests of the organization can complement negative incentives. In our research, we identified and analyzed three avenues for aligning the interests of the employee and the...
Topics: DTIC Archive, Moore,Andrew P, CARNEGIE-MELLON UNIV PITTSBURGH PA PITTSBURGH United States,...
A notable security threat that has garnered much attention in recent years is the development of anti-access/area denial (A2/AD) capabilities by international actors. In the 2015 National Military Strategy, the Chairman of the Joint Chief of Staff describes the international environment as fraught with uncertainty and characterized by rapid change and evolving security threats at all levels.2 A2/AD reflects a set of capabilities used by an actor to project power and reduce access over a...
Topics: DTIC Archive, TAGHIZADEH,SABRINA, AIR COMMAND AND STAFF COLLEGE, AIR UNIVERSITY MAXWELL AFB United...
This project aims to establish an antimicrobial and biocompatible copper coating for a standard issue antimicrobial combat wound dressing. This initial one-year project was done to provide important foundational data that will guide subsequent research efforts and position the technology for commercial development. As part of these efforts, iFyber established a number of coating parameters a number of candidate dressings that have a range of in vitro antimicrobial efficacy and biocompatibility...
Topics: DTIC Archive, Strickland, Aaron D, iFyber, LLC Ithaca United States, COPPER COATINGS, BANDAGES,...
Chronic pain is a significant problem after nerve injury from trauma or surgery. Current therapies and attempts at prevention have proven largely ineffective. Through analysis of data obtained in the Molecular Signatures of Chronic Pain Subtypes study termed Veterans Integrated Pain Evaluation Research (VIPER) (W81XWH-11-2-0003) we have discovered two novel pain pathways with potential therapeutic relevance (Wnt and TGR5). In addition, we recognize that improving the safety and efficacy of...
Topics: DTIC Archive, Van de Ven, Thomas, Duke University Durham United States, pain, pain management,...
A precisely controlled quantum system may reveal a fundamental understanding of another, less accessible system of interest. A universal quantum computer is currently out of reach, but an analogue quantum simulator that makes relevant observables, interactions and states of a quantum model accessible could permit insight into complex dynamics. Several platforms have been suggested and proof-of-principle experiments have been conducted. Here, we operate two-dimensional arrays of three trapped...
Topics: DTIC Archive, Mielenz,Manuel, Albert-Ludwigs Universitat Freiburg Freiburg Germany, quantum theory,...
Toxic industrial chemicals induce liver injury, which is difficult to diagnose without invasive procedures. Identifying indicators of end organ injury can complement exposure-based assays and improve predictive power. A multiplexed approach was used to experimentally evaluate a panel of 67 genes predicted to be associated with the fibrosis pathology by computationally mining Drug Matrix, a publicly available repository of gene microarray data. Five-day oral gavage studies in male Sprague Dawley...
Topics: DTIC Archive, Ippolito,Danielle L, Army Center for Environmental Health Research Fort Detrick...
Military communities in tactical networks must often maintain high group solidarity based on the trustworthiness of participating individual entities where collaboration is critical to performing team-oriented missions. Group trust is regarded as more important than trust of an individual entity since consensus among or compliance of participating entities with given protocols may significantly affect successful mission completion. This work introduces a game theoretic approach, namely Aoyagis...
Topics: DTIC Archive, Cho,Jin-Hee, U.S. Army Research Laboratory Adelphi United States, game theory,...
Knowledge of the general problems of internal waves and ocean mixing are important for advancing the performance of operational and climate models, as well as for understanding local problems such as pollutant dispersal and biological productivity. In the specific case of NLIWs, the currents and displacements of the waves are strong enough to impact undersea operations. More generally, most of the oceans physical and acoustic environments (particularly in straits) are severely impacted by...
Topics: DTIC Archive, Alford,Matthew H, Scripps Institution of Oceanography La Jolla United States,...
Effective and efficient mapping of permafrost subsurface composition at scales relevant to the design and maintenance of horizontal and vertical infrastructure has been a long-standing challenge. Of utmost utility would be the development of standoff measurement techniques that could discern at the meter to submeter spatial scale and up to 10 m into the subsurface the presence or absence of ice features. Ground-based geophysical measurement techniques, including ground penetrating radar,...
Topics: DTIC Archive, Barrowes,Benjamin E, Cold Regions Research and Engineering Laboratory (CRREL) Hanover...
A thermal bimorph is a thin laminate which develops curvature upon heating on account of being constructed from layers of mismatched thermal expansion coefficients. However, current bimorphs are generally limited to benign temperatures and linear temperature displacement relationships. This work develops modelling techniques and fabrication methods that facilitate the use of nonlinear-response thermal bimorphs in high-temperature morphing structures. Successful application of this work may...
Topics: DTIC Archive, Weaver,Paul, University of Bristol Bristol United Kingdom, Thermal management,...
This grant aims to improve the guarantees offered by both language-based information security mechanisms, and operating system information security mechanisms. It seeks to do so by investigating interactions between language-based and OS mechanisms for information security, and exploiting these interactions both to improve the precision of security enforcement, and to provide greater assurance of information security. This grant focuses on two key projects: language-based control of authority;...
Topics: DTIC Archive, Chong,Stephen, Harvard University Cambridge United States, computer network security,...
This proposal focuses on the analysis and design of coordination algorithms for multiple agents deployed in adversarial environments. The multi-agent systems can represent miscellaneous autonomous and semi-autonomous vehicles that are remotely controlled by operators. These groups can be subject to attacks from other external agents leading to complex networked adversarial settings. The proposal presents work in two main areas: 1) the use of a class of receding-horizon type of algorithms to...
Topics: DTIC Archive, Martinez,Sonia, CALIFORNIA UNIV SAN DIEGO LA JOLLA LA JOLLA United States,...
The objective of the Anbar Awakening project was to create an unclassified resource for trainers and educators. It is presented in multimedia to accommodate different teaching and learning styles. The project presents the Awakening movement's phases from the development of the insurgency in 2003 to the Coalition's transfer of responsibility for Al Anbar to the Iraqis in 2008. In addition, it offers analysis and lessons, many of which are transferrable to current and future conflicts. Most...
Topics: DTIC Archive, Knarr,William M, INSTITUTE FOR DEFENSE ANALYSES ALEXANDRIA VA ALEXANDRIA, Iraq,...
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This memorandum provides a brief introduction to finite rate chemistry in the framework of large eddy simulation for compressible flow fields. Particular emphasis is placed upon the filtered reaction rate expression through the use turbulent chemical closure terms. The Eddy Break-Up model is an example of this type of closure term. Within the multiphase physics computer code LESLIE3D, these algorithms are tested on a gas phase acetylene combustion problem and on a shock wave initiated droplet...
Topics: DTIC Archive, Nance,Douglas V, Air Force Research Laboratory Eglin AFB United States, flow fields,...
We estimate the impact of Title 32 Active Guard Reserve soldiers (T32 AGRs) in the Army National Guard on the deployment availability of drilling soldiers located in the same battalion. We focus on Modification Table of Organization and Equipment (MTOE) units during periods when individuals and units are not mobilized in preparation for deployment, deployed, or recently returned from deployment. The common practice of moving troops between units correlates with T32 AGR exposure levels and...
Topics: DTIC Archive, Pechacek,Julie, Institute for Defense Analyses Alexandria, national guard,...
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The reentry of service members back into family life after deployment can be extremely challenging for military couples. Understanding the factors that contribute to the reintegration difficulty of returning service members and at-home partners is essential for attracting, retaining, and safeguarding the nations best military personnel. The goal of this project is to evaluate how peoples mental health symptoms and romantic relationship characteristics predict their difficulty with...
Topics: DTIC Archive, Knobloch,Leanne K, University of Illinois Urbana United States, military personnel,...
Much as commercial firms do, terrorist groups use branding to increase support and thus their capacity to conduct operations. This thesis introduces the new concept terrorist brand exposure, as a reflection of effective brand management strategies and communications among terrorist groups. In that regard, this thesis seeks to merge two vastly different theories, brand theory and terrorism studies, into one package. The research involves a quantitative analysis of the terrorist brand exposure of...
Topics: DTIC Archive, Greaver,Bradley S, Naval Postgraduate School Monterey United States, terrorism,...
Trauma, extensive burns, bacterial infections, and acute pancreatitis (AP) are common conditions of tissue injury and immune system activation that can result in the systemic inflammatory response syndrome (SIRS). Surprisingly, about half of the patients with SIRS quickly recover, while the others develop a multiorgan dysfunction syndrome (MODS). SIRS and MODS do not occur immediately: SIRS evolves over a 4-12 hour period, while MODS evolves over12-24 hours. Vascular leak syndrome (VLS) is a...
Topics: DTIC Archive, Whitcomb,David C, The University of Pittsburgh Pittsburgh United States, VASCULAR...
This working paper derives from an ongoing research effort to improve U.S. strategic design to defeat the Islamic State (IS), a hybrid insurgent-terrorist group that currently holds territory in Iraq and Syria, and has affiliates across the world. The current strategy to degrade, defeat, and destroy the Islamic State, and American strategies to succeed in Vietnam, Afghanistan, and Iraq, reveal serious flaws in the Western approach to strategic design: ends are unclear, yet it seems hard to...
Topics: DTIC Archive, Connable,Ben, RAND National Security Research Division Santa Monica United States,...
This research is in response to a request from the United States Marine Corps Expeditionary Energy Office. The Marine Corps has identified its reliance on energy resources as a real threat to military security and a drag on the logistics tail of expeditionary operations. This research recommends that the Marine Corps prioritize development of the existing Unit Energy Manager program to address operational energy capability requirements. Long-term solutions require updating existing formal...
Topics: DTIC Archive, Wall,Jessica M, Naval Postgraduate School Monterey United States, marine corps,...
Are Vietnam and the Philippines trending more toward conflict or cooperation with China over disputed territories and resource claims in the South China Sea? This thesis investigates realist and liberal international relations theories applied to three states involved in South China Sea disputes. It reviews the history of South China Sea disputes between China, Vietnam, and the Philippines since 1988 and reviews the states growing economic interconnectedness to determine whether they have...
Topics: DTIC Archive, Gussenhoven,Michael A, Naval Postgraduate School Monterey United States,...
Defense Technical Information Archive
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This thesis seeks to answer two related questions regarding corruption and Chavismo. First, what factors contributed to the rise in Venezuelas Corruption Perception Index from 20002014? Second, what does Venezuela need to do to reverse that trend? The thesis examines Hugo Chavezs populist policies as well as two leading factors for the rise of corruptionweak governance and oil over-dependence practicesand analyzes the Resource Curse theory and Chaveznomics. Chavezs populist policies created...
Topics: DTIC Archive, Mercado,Frances V, NAVAL POSTGRADUATE SCHOOL MONTEREY CA MONTEREY United States,...
Direction finding (DF) systems are fundamental electronic support measures for electronic warfare. A number of DF techniques have been developed over the years; however, these systems are limited in bandwidth and resolution and suffer from a complex design for frequency down-conversion. An innovative design of a microwave-photonic direction finding technique for the detection and direction finding of low probability of intercept (LPI) signals is investigated in this thesis. Key advantages of...
Topics: DTIC Archive, Ong,Chee K, NAVAL POSTGRADUATE SCHOOL MONTEREY CA MONTEREY, detection, direction...
Current Marine Corps policy requires that all Marines below the rank of Gunnery Sergeant and with fewer than 13 years of service undergo annual rifle qualification. Annual marksmanship training is repetitive and only addresses the fundamentals of marksmanship, which Marines typically master in their first few years. Key features of marksmanship training are instilled at initial training for officers and enlisted Marines, but advanced training is seldom received outside infantry and select...
Topics: DTIC Archive, Martin,Travis R, Naval Postgraduate School Monterey United States, marksmanship,...
Although historically restricted from combat roles, women suffer from combat-related injuries, especially in recent conflicts where asymmetrical warfare erases distinctions between forward and rear operating areas. U.S. servicewomen who sustained combat-related injury in Operation Iraqi Freedom (OIF) or Operation Enduring Freedom (OEF) between January 2003 and May 2014 were identified from the Expeditionary Medical Encounter Database. Injuries were characterized using Abbreviated Injury Scale...
Topics: DTIC Archive, Dye,Judy L, NAVAL HEALTH RESEARCH CENTER SAN DIEGO CA SAN DIEGO United States, combat...
Following the tragic events of September 11, 2001, numerous reports came to the same conclusion: there was an urgent need to enhance information sharing throughout the homeland security community (HSC). The report of the National Commission of the Terrorist Attacks upon the United States set forth numerous failures of information sharing that occurred throughout the HSC involving events leading up to9/11, the attacks, and the response. The necessity of information to enable the fire service...
Topics: DTIC Archive, Kiesling,James W, NAVAL POSTGRADUATE SCHOOL MONTEREY CA MONTEREY United States, first...
This thesis explores the practices of six state or local law enforcement agencies in the field of maritime homeland security. Using the Delphi Survey Method on a sample of the highest-risk, most strategically located, and most commercially important ports in the United States, this thesis looks at the successes and challenges of grant funding, training practices, recovery efforts, and state government role in maritime homeland security. The resounding and underlying theme of the best practices...
Topics: DTIC Archive, Nichols,Kirk L, Naval Postgraduate School Monterey United States, maritime security,...
This thesis poses the question, What is the nature of the relationships between social embeddedness, structural efficiency, and organizational behavior within dark networks? The objectives of this thesis are twofold. The primary objective is to illuminate the interaction between embeddedness, structure, and activity within dark networks, the aim being to study if changes in embeddedness manifest in observable fluctuations in a networks topography or behavior. The secondary objective is to...
Topics: DTIC Archive, Raabe,Leopele S, Naval Postgraduate School Monterey United States, NETWORKS,...
In its fight against the Islamic State of Iraq and al-Sham (ISIS), the United States has developed five lines of effort (LOEs): provide military support to our partners; impede the flow of foreign fighters to ISIS; stop ISISs financing and funding; address humanitarian crises in the region; and expose ISISs true nature. A much addressed question in the media as well as scholarly analyses is whether these LOEs will be effective in defeating the ISIS insurgency in Iraq, or whether the United...
Topics: DTIC Archive, Holaday,Joshua B, AIR UNIV MAXWELL AFB AL MAXWELL AFB United States, civil war,...
In response to a shifting National Military Strategy that renewed the focus of combat operations on smaller, projectable, and dynamic joint fight entities, both the Army and Navy reviewed requirements to address capability shortfalls in either their force structure or operational warfighting concepts, or both. Both services initial capability reviews resulted in a series of Advanced Concept Technology Demonstrations (ACTD) designed to explore the military utility of converted commercial,...
Topics: DTIC Archive, Watson,Brian Sr T, Naval Postgraduate School Monterey United States, military...
Condition-based maintenance (CBM) entails performing maintenance only when needed to save on resources and cost. Formulating a model that reflects the behavior of the marine diesel engine in its normal operating conditions would aid in making predictions of the behavior of a condition monitoring parameter. Modeling for CBM is a data-dependent process. Data acquisition, processing, and analysis are required for modeling the behavior of the normal operating conditions of the diesel engine. This...
Topics: DTIC Archive, Yue,Siew P, NAVAL POSTGRADUATE SCHOOL MONTEREY CA MONTEREY United States, diesel...
The overall goal of the project was to develop an animal model of the focal dystonia benign essential blepharospasm. Consistent with the widely held view that dystonia results from an interaction between a predisposing condition and an environmental trigger, we proposed to use7 Hz deep brain stimulation of the basal ganglia as the predisposing condition and dry eye as an environmental trigger. Based on experiments during the 1st year of the grant, our publication, Evinger, J. Neuro-Ophthalmol....
Topics: DTIC Archive, Evinger,Leslie, The Research Foundation of State University Stony Brook, eye...
Defense Technical Information Archive
- Defense Technical Information Center
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This thesis examines the roles of decision makers in three phases of a special operation: the approval phase, the preparation phase, and the execution phase. The author argues that the level of decision makers involvement should be high in the approval phase, medium in the preparation phase, and low in the execution phase. Four special operationsOperation Thunderbolt, Operation Nimrod, Operation Eagle Claw, and the Moscow Theater Hostage Crisiswhich were conducted by different countries Special...
Topics: DTIC Archive, Aykac,Kazim, Naval Postgraduate School Monterey United States, decision making,...
Defense Technical Information Archive
- Defense Technical Information Center
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Over the last 12 months of this award, we have focused on developing an in-depth understanding of the immune system in the setting of the tumor microenvironment. We have made progress in developing methods to better analyze the relationships between primary tumor and metastatic growths with their surrounding microenvironments, and implications for immune response and dendritic cell function in vitro using 3D microculture techniques. We have further investigated and tested alternative methods...
Topics: DTIC Archive, Lee,Peter P, Beckman Research Institute of City of Hope Duarte United States, cell...
Prostate cancer is commonly multiclonal, meaning that most men with prostate cancer have multiple, genetically distinct cancers. Pathologists cannot assess clonally by routine microscopic evaluation, and hence multiclonality is not incorporated into routinely reported pathological parameters, such as the number of cores with cancer. Given the importance of routine pathological parameters in prostate cancer prognosis, the potential to refine these parameters through assessing multiclonality...
Topics: DTIC Archive, Tomlins,Scott A, Regents of the University of Michigan Ann Arbor United States, gene...
In 2014, a Defense Science Board Task Force was convened in order to assess and explore new technologies that would aid in nuclear proliferation monitoring. One of their recommendations was for the director of National Intelligence to explore ways that crowdsourced geospatial imagery technologies could aid existing governmental efforts. Our research builds directly on this recommendation and provides feedback on some of the most successful examples of crowdsourced geospatial data (CGD).As of...
Topics: DTIC Archive, Leno,Kenyon M, NAVAL POSTGRADUATE SCHOOL MONTEREY CA MONTEREY United States, counter...
Defense Technical Information Archive
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The United States Air Force (USAF) faces tremendous leadership challenges as it enters its 25th year of continuous combat operations. Manning shortfalls, reduced budgets and a myriad of other complex challenges have increased the stress placed upon Air Force leaders and followers alike. While caring for Airmen and their families the USAF Chaplain Corps has been navigating leadership challenges as well. These challenges have compromised the organizational health of the Chaplain Corps. This lack...
Topics: DTIC Archive, Boyd,Matthew F, Air Command and Staff College, Air University Maxwell Air Force Base...
Defense Technical Information Archive
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Due to the complexity of cyberspace and the diversity of threats that operate in the new domain, current US cyber strategy has not proven effective. This paper dissects the cyber threat landscape and how advanced threats operate in order to devise an effective, adaptive strategy for US cybersecurity. US cybersecurity strategy must be threat-focused and threat-aware with capabilities built to evolve as threats evolve. Threat agnostic strategy that simply builds better perimeter defenses around...
Topics: DTIC Archive, Smith,Zachary M, Air Command and Staff College, Air University Maxwell Air Force Base...
Biosensors based on organic thin film transistor technology offer the exciting prospect of detecting and identifying peptides; biomarkers found in bodily fluids. This development would assist in the monitoring or identification of medical diseases and facilitate rapid, point-of-care testing. In particular, neuropeptide Y is a highly abundant neurotransmitter with links to many important physiological functions, including stress response. Its rapid detection provides an opportunity to identify...
Topics: DTIC Archive, Dastoor, Paul, UNIVERSITY OF NEWCASTLE RESEARCH SERVICES GRANTS OFFICE CALLAGHAN...
Topics: DTIC Archive, Navone,Nora M, University of Michigan Ann Arbor United States
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MIT LL and CSAIL have enjoyed several collaborations over the past decade. Collaborative projects have been very diverse, spanning several areas of CSAIL concentration, including robotics, big data analytics, wireless communications, computing architectures and technologies, and cyber security. Nevertheless, the consensus of the committee is that, given the large overlap in interests and the dramatically growing importance to national security of several key CSAIL core areas, collaborations and...
Topics: DTIC Archive, Bond,Robert A, MASSACHUSETTS INST OF TECH LEXINGTON LEXINGTON United States,...
The study during the reporting period has used blood samples from leukemia patients who received therapeutic radiation for discovery of biomarkers. This could be used for exposure estimation in soldiers and emergency responders involved in nuclear war. The method for discovery and validation of biomarkers was optimized using samples collected from patients enrolled in two clinical trials. The utility of selected biomarkers identified from our earlier animal models has been validated and...
Topics: DTIC Archive, Jacob,Naduparambil K, The Ohio State University Columbus United States, biological...
The goal of this project is to define the biomarker profile of TBI-associated cognitive impairment (CI) in veterans and compare it to that of veterans with Alzheimers Disease (AD) and to age-matched controls. Our overall hypothesis is that TBI-associated CI involves a unique biomarker profile that has features distinguishable from AD and normal aging. Specifically, we hypothesize that: 1) patients with TBI associated CI will have higher phospho-tau/total tau ratio than controls who have not had...
Topics: DTIC Archive, Yaffe,Kristine, Northern California Institute for Research and Education CONTRACTING...
In second year of the award (2016), 4 meritorious students were selected under HBCU Summer Undergraduate Training Program in Prostate Cancer by USU-CPDR and UDC selection committee to provide motivating experience in the state-of-the-art CaP research. The main objectives are: (a) Recruit and motivate highly qualified undergraduate trainees from UDC, (b) expose UDC students to an intellectual environment that promotes state-ofthe-art hands-on training and education in CaP research through...
Topics: DTIC Archive, Srivastava,Shiv, Henry M. Jackson Foundation for the Advancement of Military Medicine...