Skip to main content

Additional Collections

Additional collections of scanned books, articles, and other texts (usually organized by topic) are presented here.

More right-solid
More right-solid
SHOW DETAILS
up-solid down-solid
eye
Title
Date Archived
Creator
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
The selected plan is a coordinated effort to combine the most economical and desirable aspects of a multipurpose reservoir and levees to provide 30-year flood protection for the Sulphur River Basin in northeast Texas. The draft EIS plan, which included extensive channelization, received authorization for construction in 1955 and work began on the channel and levees feature shortly thereafter. In May 1971, the US District Court for the Eastern District of Texas, acting on a motion for...
Topics: DTIC Archive, ARMY ENGINEER DISTRICT NEW ORLEANS LA, *CHANNELS(WATERWAYS), *RESERVOIRS,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
The selected plan is a coordinated effort to combine the most economical and desirable aspects of a multipurpose reservoir and levees to provide 30-year flood protection for the Sulphur River Basin in northeast Texas. The draft EIS plan, which included extensive channelization, received authorization for construction in 1955 and work began on the channel and levees feature shortly thereafter. In May 1971, the US District Court for the Eastern District of Texas, acting on a motion for...
Topics: DTIC Archive, ARMY ENGINEER DISTRICT NEW ORLEANS LA, *CHANNELS(WATERWAYS), *RESERVOIRS,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
The selected plan is a coordinated effort to combine the most economical and desirable aspects of a multipurpose reservoir and levees to provide 30-year flood protection for the Sulphur River Basin in northeast Texas. The draft EIS plan, which included extensive channelization, received authorization for construction in 1955 and work began on the channel and levees feature shortly thereafter. In May 1971, the US District Court for the Eastern District of Texas, acting on a motion for...
Topics: DTIC Archive, ARMY ENGINEER DISTRICT NEW ORLEANS LA, *CHANNELS(WATERWAYS), *RESERVOIRS,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
The selected plan is a coordinated effort to combine the most economical and desirable aspects of a multipurpose reservoir and levees to provide 30-year flood protection for the Sulphur River Basin in northeast Texas. The draft EIS plan, which included extensive channelization, received authorization for construction in 1955 and work began on the channel and levees feature shortly thereafter. In May 1971, the US District Court for the Eastern District of Texas, acting on a motion for...
Topics: DTIC Archive, ARMY ENGINEER DISTRICT NEW ORLEANS LA, *CHANNELS(WATERWAYS), *RESERVOIRS,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
The selected plan is a coordinated effort to combine the most economical and desirable aspects of a multipurpose reservoir and levees to provide 30-year flood protection for the Sulphur River Basin in northeast Texas. The draft EIS plan, which included extensive channelization, received authorization for construction in 1955 and work began on the channel and levees feature shortly thereafter. In May 1971, the US District Court for the Eastern District of Texas, acting on a motion for...
Topics: DTIC Archive, ARMY ENGINEER DISTRICT NEW ORLEANS LA, *CHANNELS(WATERWAYS), *RESERVOIRS,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
The selected plan is a coordinated effort to combine the most economical and desirable aspects of a multipurpose reservoir and levees to provide 30-year flood protection for the Sulphur River Basin in northeast Texas. The draft EIS plan, which included extensive channelization, received authorization for construction in 1955 and work began on the channel and levees feature shortly thereafter. In May 1971, the US District Court for the Eastern District of Texas, acting on a motion for...
Topics: DTIC Archive, ARMY ENGINEER DISTRICT NEW ORLEANS LA, *CHANNELS(WATERWAYS), *RESERVOIRS,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
The selected plan is a coordinated effort to combine the most economical and desirable aspects of a multipurpose reservoir and levees to provide 30-year flood protection for the Sulphur River Basin in northeast Texas. The draft EIS plan, which included extensive channelization, received authorization for construction in 1955 and work began on the channel and levees feature shortly thereafter. In May 1971, the US District Court for the Eastern District of Texas, acting on a motion for...
Topics: DTIC Archive, ARMY ENGINEER DISTRICT NEW ORLEANS LA, *CHANNELS(WATERWAYS), *RESERVOIRS,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
The selected plan is a coordinated effort to combine the most economical and desirable aspects of a multipurpose reservoir and levees to provide 30-year flood protection for the Sulphur River Basin in northeast Texas. The draft EIS plan, which included extensive channelization, received authorization for construction in 1955 and work began on the channel and levees feature shortly thereafter. In May 1971, the US District Court for the Eastern District of Texas, acting on a motion for...
Topics: DTIC Archive, ARMY ENGINEER DISTRICT NEW ORLEANS LA, *CHANNELS(WATERWAYS), *RESERVOIRS,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
The selected plan is a coordinated effort to combine the most economical and desirable aspects of a multipurpose reservoir and levees to provide 30-year flood protection for the Sulphur River Basin in northeast Texas. The draft EIS plan, which included extensive channelization, received authorization for construction in 1955 and work began on the channel and levees feature shortly thereafter. In May 1971, the US District Court for the Eastern District of Texas, acting on a motion for...
Topics: DTIC Archive, ARMY ENGINEER DISTRICT NEW ORLEANS LA, *CHANNELS(WATERWAYS), *RESERVOIRS,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
The selected plan is a coordinated effort to combine the most economical and desirable aspects of a multipurpose reservoir and levees to provide 30-year flood protection for the Sulphur River Basin in northeast Texas. The draft EIS plan, which included extensive channelization, received authorization for construction in 1955 and work began on the channel and levees feature shortly thereafter. In May 1971, the US District Court for the Eastern District of Texas, acting on a motion for...
Topics: DTIC Archive, ARMY ENGINEER DISTRICT NEW ORLEANS LA, *CHANNELS(WATERWAYS), *RESERVOIRS,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Agarose gel electrophoresis was employed to screen nine strains of Legionella-like bacteria and one strain of Legionella pneumophila for the presence of extrachromosomal deoxyribonucleic acid. Cryptic plasmids with molecular weights ranging from 46.6 x 10 (expn 6) to 59.8 x 10 (expn 6) were found in three of the isolates examined.
Topics: DTIC Archive, Mikesell, Perry, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Agarose gel electrophoresis was employed to screen nine strains of Legionella-like bacteria and one strain of Legionella pneumophila for the presence of extrachromosomal deoxyribonucleic acid. Cryptic plasmids with molecular weights ranging from 46.6 x 10 (expn 6) to 59.8 x 10 (expn 6) were found in three of the isolates examined.
Topics: DTIC Archive, Mikesell, Perry, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Agarose gel electrophoresis was employed to screen nine strains of Legionella-like bacteria and one strain of Legionella pneumophila for the presence of extrachromosomal deoxyribonucleic acid. Cryptic plasmids with molecular weights ranging from 46.6 x 10 (expn 6) to 59.8 x 10 (expn 6) were found in three of the isolates examined.
Topics: DTIC Archive, Mikesell, Perry, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Agarose gel electrophoresis was employed to screen nine strains of Legionella-like bacteria and one strain of Legionella pneumophila for the presence of extrachromosomal deoxyribonucleic acid. Cryptic plasmids with molecular weights ranging from 46.6 x 10 (expn 6) to 59.8 x 10 (expn 6) were found in three of the isolates examined.
Topics: DTIC Archive, Mikesell, Perry, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Agarose gel electrophoresis was employed to screen nine strains of Legionella-like bacteria and one strain of Legionella pneumophila for the presence of extrachromosomal deoxyribonucleic acid. Cryptic plasmids with molecular weights ranging from 46.6 x 10 (expn 6) to 59.8 x 10 (expn 6) were found in three of the isolates examined.
Topics: DTIC Archive, Mikesell, Perry, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Agarose gel electrophoresis was employed to screen nine strains of Legionella-like bacteria and one strain of Legionella pneumophila for the presence of extrachromosomal deoxyribonucleic acid. Cryptic plasmids with molecular weights ranging from 46.6 x 10 (expn 6) to 59.8 x 10 (expn 6) were found in three of the isolates examined.
Topics: DTIC Archive, Mikesell, Perry, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Defense Technical Information Archive
texts
eye 0
favorite 0
comment 0
New human estimates for chlorine inhalation lethality as a function of exposure duration were derived via a review and statistical analysis of existing mammalian lethality data. Such estimates are needed to support risk assessments and casualty predictions involving airborne releases of chlorine. At present, casualty predictions for such releases are at odds with what has been observed historically; the predicted downwind hazard area has often been much larger than what was actually observed....
Topics: DTIC Archive, Sommerville,Douglas R, US Army Edgewood Chemical Biological Center Aberdeen Proving...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Agarose gel electrophoresis was employed to screen nine strains of Legionella-like bacteria and one strain of Legionella pneumophila for the presence of extrachromosomal deoxyribonucleic acid. Cryptic plasmids with molecular weights ranging from 46.6 x 10 (expn 6) to 59.8 x 10 (expn 6) were found in three of the isolates examined.
Topics: DTIC Archive, Mikesell, Perry, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Pulmonary arterial hypertension (PAH) is associated with increased vascular resistance, sustained contraction, and enhanced proliferation of pulmonary arterial smooth muscle cells (PASMCs). The underlying idea of this project is that the currently limited treatments for PAH represent an unmet medical need for soldiers, veterans and those in the general population. We are testing the hypothesis that the discovery of novel (i.e., not previously recognized) G-protein-coupled receptors (GPCRs) and...
Topics: DTIC Archive, Insel,Paul, The Regents of the University of California San Diego La Jolla United...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Agarose gel electrophoresis was employed to screen nine strains of Legionella-like bacteria and one strain of Legionella pneumophila for the presence of extrachromosomal deoxyribonucleic acid. Cryptic plasmids with molecular weights ranging from 46.6 x 10 (expn 6) to 59.8 x 10 (expn 6) were found in three of the isolates examined.
Topics: DTIC Archive, Mikesell, Perry, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
There is a critical need for health care transition (HCT) services and health-related independence (HRI) for youth with ASD. Existing HCT measurement tools fail to address youth and caregiver perspectives and no existing measurement tools examine HRI among youth with ASD. In Aim 1 of this study we explored HCT and HRI experiences and needs of youth with ASD and their caregivers utilizing qualitative methods. We recruited 61 caregivers and 43 young adults to participate and completed focus...
Topics: DTIC Archive, Cheak-Zamora,Nancy, University of Missouri Columbia United States, YOUTH, QUALITY OF...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Agarose gel electrophoresis was employed to screen nine strains of Legionella-like bacteria and one strain of Legionella pneumophila for the presence of extrachromosomal deoxyribonucleic acid. Cryptic plasmids with molecular weights ranging from 46.6 x 10 (expn 6) to 59.8 x 10 (expn 6) were found in three of the isolates examined.
Topics: DTIC Archive, Mikesell, Perry, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
This study will recruit wounded warriors with severe extremity trauma, which places them at high risk for heterotopic ossification (HO); bone formation at abnormal sites, which causes pain, limits motion and/or limits the use of a prosthetic device. There are three goals: 1) to understand the mechanisms involved in HO; 2) to define accurate and practical methods to predict where HO will develop; and 3) to define potential therapies for prevention or mitigation of HO.
Topics: DTIC Archive, Davis,Thomas, The Geneva Foundation Tacoma United States, TRAUMA, EXTREMITIES, WOUNDS...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Agarose gel electrophoresis was employed to screen nine strains of Legionella-like bacteria and one strain of Legionella pneumophila for the presence of extrachromosomal deoxyribonucleic acid. Cryptic plasmids with molecular weights ranging from 46.6 x 10 (expn 6) to 59.8 x 10 (expn 6) were found in three of the isolates examined.
Topics: DTIC Archive, Mikesell, Perry, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Castration-resistant prostate cancer (CRPC) is a lethal disease. We lack standard biomarkers to predict hormonal sensitivity of tumors, and we need new targets for therapy to prevent or treat CRPC. The selection theory predicts that pre-existing androgen-independent prostate cancer cells (termed lurker cells) contribute to CRPC, as they are not targeted by androgen deprivation therapy and may be capable of regenerating the tumor. Therefore, targeting these predicted lurker cells in combination...
Topics: DTIC Archive, Goldstein,Andrew, University of California, Los Angeles Los Angeles United States,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
A chemically defined medium containing 18 amino acids, inorganic salts, rhamnose, choline, and ferric pyrophosphate has been developed. The final concentrations of salts and amino acids were modeled after years extract. This medium supported the growth of four serogroups of Legionella pneumophila. Growth in shake cultures at 37 deg C produced a lag time of approximately 5 h and a generation time of 4 h with a maximum growth yield of 10 (expn 9) colony-forming units per ml. A soluble brown...
Topics: DTIC Archive, Ristroph, Joseph D, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
With the goal of conducting the most comprehensive study of mTBI to date, we hypothesize that there will be a significant correlation between biomechanical, clinical, neurobiological, and neuroradiological markers of mTBI, which will more fully inform a neurobiopsychosocial model of mTBI. With the goal of baseline testing 900 athletes and enrolling 50 injured athletes and 50 contact and 50 non-contact controls over the course of 3 years, the project is progressing on schedule. We baseline...
Topics: DTIC Archive, McCrea,Michael, Medical College of Wisconsin Milwaukee United States, TRAUMATIC BRAIN...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
A chemically defined medium containing 18 amino acids, inorganic salts, rhamnose, choline, and ferric pyrophosphate has been developed. The final concentrations of salts and amino acids were modeled after years extract. This medium supported the growth of four serogroups of Legionella pneumophila. Growth in shake cultures at 37 deg C produced a lag time of approximately 5 h and a generation time of 4 h with a maximum growth yield of 10 (expn 9) colony-forming units per ml. A soluble brown...
Topics: DTIC Archive, Ristroph, Joseph D, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
The telerehabilitation for OEF/OIF returnees with mild or moderate combat related Traumatic Brain Injury (TBI) has as its objectives 1) care coordination for wounded veterans using distance technology via the internet and 2) monitoring of physical and mental health outcomes using a variety of instruments. We have enrolled a total of 75 veterans in the study. We have collected baseline, 6 and 12 month health status data on most veterans. Our findings indicate that 1) Functional capabilities...
Topics: DTIC Archive, Siddharthan,Kris, Tampa VA Research and Education Foundation Zephyrhills United...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
A chemically defined medium containing 18 amino acids, inorganic salts, rhamnose, choline, and ferric pyrophosphate has been developed. The final concentrations of salts and amino acids were modeled after years extract. This medium supported the growth of four serogroups of Legionella pneumophila. Growth in shake cultures at 37 deg C produced a lag time of approximately 5 h and a generation time of 4 h with a maximum growth yield of 10 (expn 9) colony-forming units per ml. A soluble brown...
Topics: DTIC Archive, Ristroph, Joseph D, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
The major objective of the PCRP postdoctoral training award was to provide training and opportunities for the principal investigator (PI) to further her development as an independent prostate cancer researcher in the field of molecular epidemiology. During the award period the PI performed research incorporating tissue-level biomarker data into epidemiologic studies of prostate cancer progression to investigate the relationship between obesity, the tumor microenvironment, and lethal prostate...
Topics: DTIC Archive, Noonan,Ericka, Harvard T. H. Chan School of Public Health Boston United States,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
A chemically defined medium containing 18 amino acids, inorganic salts, rhamnose, choline, and ferric pyrophosphate has been developed. The final concentrations of salts and amino acids were modeled after years extract. This medium supported the growth of four serogroups of Legionella pneumophila. Growth in shake cultures at 37 deg C produced a lag time of approximately 5 h and a generation time of 4 h with a maximum growth yield of 10 (expn 9) colony-forming units per ml. A soluble brown...
Topics: DTIC Archive, Ristroph, Joseph D, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Prostate cancer cells were transfected with claudin siRNA duplexes using Lipofectamine RNAiMAX (Invitrogen) as well as the appropriate controls including vehicle, non-targeting siRNA (siSC5) (negative control) and glyceraldehyde-3-phosphate dehydrogenase (GAPD) (positive control). A time course and concentration curve was completed to determine the maximum down-regulation of claudin-3 and claudin-4 expression. In addition, cytotoxicity assays were performed to determine the number of viable...
Topics: DTIC Archive, Martin,Darryl, Yale University New Haven United States, prostate cancer, magnetic...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
A chemically defined medium containing 18 amino acids, inorganic salts, rhamnose, choline, and ferric pyrophosphate has been developed. The final concentrations of salts and amino acids were modeled after years extract. This medium supported the growth of four serogroups of Legionella pneumophila. Growth in shake cultures at 37 deg C produced a lag time of approximately 5 h and a generation time of 4 h with a maximum growth yield of 10 (expn 9) colony-forming units per ml. A soluble brown...
Topics: DTIC Archive, Ristroph, Joseph D, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK...
Broadly, TATRCs aim is to explore science and engineering technologies ahead of programmed research, leveraging other programs and collaborative relationships to provide maximal benefit to military medicine. Simultaneously, TATRC aims to be the government model of opportunity-driven research agility. To that end, TATRC invests in cutting-edge technologies, through congressionally directed and other funding programs, and works in other ways with research partners nationwide to develop key...
Topics: DTIC Archive, Hull,Cheryl, The Henry M. Jackson Foundation for the Advancement of Military...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
A chemically defined medium containing 18 amino acids, inorganic salts, rhamnose, choline, and ferric pyrophosphate has been developed. The final concentrations of salts and amino acids were modeled after years extract. This medium supported the growth of four serogroups of Legionella pneumophila. Growth in shake cultures at 37 deg C produced a lag time of approximately 5 h and a generation time of 4 h with a maximum growth yield of 10 (expn 9) colony-forming units per ml. A soluble brown...
Topics: DTIC Archive, Ristroph, Joseph D, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
The overall goal of this work is to increase the availability of critical mouse models of human muscular dystrophy (MD) for both hypothesis testing and preclinical therapy development. Our multidisciplinary team from The Jackson Laboratory (JAX) and the Childrens National Medical Center (CNMC) has expertise in MD, repository management, mouse models, and preclinical testing. Over the course of this funding, Drs. Lutz and Cox at JAX have added 15 new strains to the MD Repository (Aim1) to...
Topics: DTIC Archive, Cox,Gregory A, The Jackson Laboratory Bar Harbor United States, Genetic diseases,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
A chemically defined medium containing 18 amino acids, inorganic salts, rhamnose, choline, and ferric pyrophosphate has been developed. The final concentrations of salts and amino acids were modeled after years extract. This medium supported the growth of four serogroups of Legionella pneumophila. Growth in shake cultures at 37 deg C produced a lag time of approximately 5 h and a generation time of 4 h with a maximum growth yield of 10 (expn 9) colony-forming units per ml. A soluble brown...
Topics: DTIC Archive, Ristroph, Joseph D, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
This project continues to be a biomarker discovery program focusing on the causes of persistent pain after traumatic amputation in the combat setting. In the third year we have: 1) maintained the necessary regulatory approval at WRNMMC and Duke University. We have: 1) obtained and maintained documents for approval by MRMC; 2) completed patient enrollment at 124 patients; 3) maintained our interactive, secure web based data collection system; 4) populated our biorepository at Duke with...
Topics: DTIC Archive, Shaw,Andrew D, Duke University Durham United States, pain, wounds and injuries,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
A chemically defined medium containing 18 amino acids, inorganic salts, rhamnose, choline, and ferric pyrophosphate has been developed. The final concentrations of salts and amino acids were modeled after years extract. This medium supported the growth of four serogroups of Legionella pneumophila. Growth in shake cultures at 37 deg C produced a lag time of approximately 5 h and a generation time of 4 h with a maximum growth yield of 10 (expn 9) colony-forming units per ml. A soluble brown...
Topics: DTIC Archive, Ristroph, Joseph D, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
A chemically defined medium containing 18 amino acids, inorganic salts, rhamnose, choline, and ferric pyrophosphate has been developed. The final concentrations of salts and amino acids were modeled after years extract. This medium supported the growth of four serogroups of Legionella pneumophila. Growth in shake cultures at 37 deg C produced a lag time of approximately 5 h and a generation time of 4 h with a maximum growth yield of 10 (expn 9) colony-forming units per ml. A soluble brown...
Topics: DTIC Archive, Ristroph, Joseph D, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Wnt/beta-Catenin signaling and associated target genes are implicated in the establishment of bone metastasisand in the development of castration resistant prostate cancer. Our previous studies have shown that Foxa2 is aWnt/beta-catenin target gene in prostates. Our preliminary study suggests a WntFoxa2CXCR4 axis that isinvolved in PCa bone metastasis, and activation of this axis provides survival mechanisms for PCa cellsfollowing androgen deprivation. The hypothesis is that the...
Topics: DTIC Archive, Yu,Xiuping, Vanderbilt University Medical Center Nashville, prostate cancer,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
A chemically defined medium containing 18 amino acids, inorganic salts, rhamnose, choline, and ferric pyrophosphate has been developed. The final concentrations of salts and amino acids were modeled after years extract. This medium supported the growth of four serogroups of Legionella pneumophila. Growth in shake cultures at 37 deg C produced a lag time of approximately 5 h and a generation time of 4 h with a maximum growth yield of 10 (expn 9) colony-forming units per ml. A soluble brown...
Topics: DTIC Archive, Ristroph, Joseph D, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Bilateral ovarian interstitial cell masses have been described in the owl monkey (Aotus trivirgatus) and squirrel monkey (Saimiri sciureus) and are believed to be a normal developmental change in mature females of these species. A 6-year-old female woolly monkey had bilateral accumulation of interstitial cell masses in the ovaries. The ovaries were ellipsoidal, 17 mm long, and 12 and 14 mm in diameter respectively. The cortical and medullary portions of both ovaries were indistinct, replaced by...
Topics: DTIC Archive, Elwell, M R, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
This single-blinded, RCT will: 1) evaluate effects of Transcendental Meditation (TM) vs. Prolonged Exposure (PE) and PTSD health education control (EC), using the Clinician Administered PTSD Scale (CAPS) (primary outcome); 2) evaluate effects of TM vs. controls on PTSD symptoms (PCL-M), depressive symptoms and other psychological distress measures, quality of life, and physiological/biochemical stress markers; and 3) evaluate treatment compliance. The study will enroll 210 subjects (70 per...
Topics: DTIC Archive, Nidich,Sanford, Maharishi University of Management Research Institute Maharishi Vedic...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Bilateral ovarian interstitial cell masses have been described in the owl monkey (Aotus trivirgatus) and squirrel monkey (Saimiri sciureus) and are believed to be a normal developmental change in mature females of these species. A 6-year-old female woolly monkey had bilateral accumulation of interstitial cell masses in the ovaries. The ovaries were ellipsoidal, 17 mm long, and 12 and 14 mm in diameter respectively. The cortical and medullary portions of both ovaries were indistinct, replaced by...
Topics: DTIC Archive, Elwell, M R, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Topics: DTIC Archive, Ryan,Colm, Raytheon BBN Technologies Corp. Cambridge United States
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Bilateral ovarian interstitial cell masses have been described in the owl monkey (Aotus trivirgatus) and squirrel monkey (Saimiri sciureus) and are believed to be a normal developmental change in mature females of these species. A 6-year-old female woolly monkey had bilateral accumulation of interstitial cell masses in the ovaries. The ovaries were ellipsoidal, 17 mm long, and 12 and 14 mm in diameter respectively. The cortical and medullary portions of both ovaries were indistinct, replaced by...
Topics: DTIC Archive, Elwell, M R, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Defense Technical Information Archive
texts
eye 0
favorite 0
comment 0
Mechanical testing of the finalized fixator design was completed during course of current project year. Using cadaveric sheep tibiae it was found that when the fixator was modulated from low to high stiffness, the stiffness doubled, which is sufficiently close to desired increment of 2.5-fold to justify the in vivo studies on living sheep. To confirm that the fixator could bear the forces imposed by adult, ambulating sheep, a plastic yield point above 500N was determined. Moreover, negligible...
Topics: DTIC Archive, Evans,Christopher H, Mayo Clinic Rochester United States, MEDICAL RESEARCH
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Bilateral ovarian interstitial cell masses have been described in the owl monkey (Aotus trivirgatus) and squirrel monkey (Saimiri sciureus) and are believed to be a normal developmental change in mature females of these species. A 6-year-old female woolly monkey had bilateral accumulation of interstitial cell masses in the ovaries. The ovaries were ellipsoidal, 17 mm long, and 12 and 14 mm in diameter respectively. The cortical and medullary portions of both ovaries were indistinct, replaced by...
Topics: DTIC Archive, Elwell, M R, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
The primary goal of this research effort is to determine the potential viability of the Lyric device both as a deployable hearing aid for Service Members with existing hearing loss and, in the future, as a possible form factor for a transparent hearing protection device that could protect the hearing of normal-hearing listeners without degrading auditory situational awareness. Electroacoustic magnetic interference testing demonstrated no measurable interference between the Lyric device and...
Topics: DTIC Archive, Brungart,Douglas, The Henry M. Jackson Foundation for the Advancement of Military...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Bilateral ovarian interstitial cell masses have been described in the owl monkey (Aotus trivirgatus) and squirrel monkey (Saimiri sciureus) and are believed to be a normal developmental change in mature females of these species. A 6-year-old female woolly monkey had bilateral accumulation of interstitial cell masses in the ovaries. The ovaries were ellipsoidal, 17 mm long, and 12 and 14 mm in diameter respectively. The cortical and medullary portions of both ovaries were indistinct, replaced by...
Topics: DTIC Archive, Elwell, M R, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Bilateral ovarian interstitial cell masses have been described in the owl monkey (Aotus trivirgatus) and squirrel monkey (Saimiri sciureus) and are believed to be a normal developmental change in mature females of these species. A 6-year-old female woolly monkey had bilateral accumulation of interstitial cell masses in the ovaries. The ovaries were ellipsoidal, 17 mm long, and 12 and 14 mm in diameter respectively. The cortical and medullary portions of both ovaries were indistinct, replaced by...
Topics: DTIC Archive, Elwell, M R, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Bilateral ovarian interstitial cell masses have been described in the owl monkey (Aotus trivirgatus) and squirrel monkey (Saimiri sciureus) and are believed to be a normal developmental change in mature females of these species. A 6-year-old female woolly monkey had bilateral accumulation of interstitial cell masses in the ovaries. The ovaries were ellipsoidal, 17 mm long, and 12 and 14 mm in diameter respectively. The cortical and medullary portions of both ovaries were indistinct, replaced by...
Topics: DTIC Archive, Elwell, M R, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Bilateral ovarian interstitial cell masses have been described in the owl monkey (Aotus trivirgatus) and squirrel monkey (Saimiri sciureus) and are believed to be a normal developmental change in mature females of these species. A 6-year-old female woolly monkey had bilateral accumulation of interstitial cell masses in the ovaries. The ovaries were ellipsoidal, 17 mm long, and 12 and 14 mm in diameter respectively. The cortical and medullary portions of both ovaries were indistinct, replaced by...
Topics: DTIC Archive, Elwell, M R, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Topics: DTIC Archive, Elwell, M R, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Defense Technical Information Archive
texts
eye 0
favorite 0
comment 0
Metalorganic frameworks (MOFs) built up from Zr6-based nodes andmulti-topic carboxylate linkers have attracted attention due to theirfavourable thermal and chemical stability. However, the hydrolyticstability of some of these Zr6-based MOFs has recently been questioned.Herein we demonstrate that two Zr6-based frameworks,namely UiO-67 and NU-1000, are stable towards linker hydrolysis inH2O, but collapse during activation from H2O. Importantly, this frameworkcollapse can be overcome by utilizing...
Topics: DTIC Archive, Mondloch,Joseph E, Northwestern University Evanston Campus Evanston United States,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Bilateral ovarian interstitial cell masses have been described in the owl monkey (Aotus trivirgatus) and squirrel monkey (Saimiri sciureus) and are believed to be a normal developmental change in mature females of these species. A 6-year-old female woolly monkey had bilateral accumulation of interstitial cell masses in the ovaries. The ovaries were ellipsoidal, 17 mm long, and 12 and 14 mm in diameter respectively. The cortical and medullary portions of both ovaries were indistinct, replaced by...
Topics: DTIC Archive, Elwell, M R, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Intracerebroventricular (icv) injection of endogenous pyrogen (EP) into rats causes dose-related fever. To compare this procedure with the usual assay method, iv injection into rabbits, a preparation of crude rabbit EP was titrated by both methods. The rat icv injcetion procedure gave results simil in linearity and magnitude of response to the conventional rabbit iv method, but was found to be at least 50-fold more sensitive. The icv assay worked for human as well as rabbit EP and for partially...
Topics: DTIC Archive, Critz, Walter J, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Intracerebroventricular (icv) injection of endogenous pyrogen (EP) into rats causes dose-related fever. To compare this procedure with the usual assay method, iv injection into rabbits, a preparation of crude rabbit EP was titrated by both methods. The rat icv injcetion procedure gave results simil in linearity and magnitude of response to the conventional rabbit iv method, but was found to be at least 50-fold more sensitive. The icv assay worked for human as well as rabbit EP and for partially...
Topics: DTIC Archive, Critz, Walter J, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Defense Technical Information Archive
Jan 27, 2020 Defense Technical Information Center
texts
eye 0
favorite 0
comment 0
Metastasis is a multistep process whereby cells from the primary tumor undergo an epithelial to mesenchymal transition (EMT) allowing for dissemination into metastatic niches such as the brain, bone and liver. Once attaining the metastatic organ the rate-limiting step in metastasis is that the cells must survive in a new niche and proliferate to form a frank metastasis. For reasons that are still incompletely understood, many breast cancer cells can remain dormant for years to even over a...
Topics: DTIC Archive, Wheeler,Sarah, University of Pittsburgh Pittsburgh United States, breast cancer,...
Intracerebroventricular (icv) injection of endogenous pyrogen (EP) into rats causes dose-related fever. To compare this procedure with the usual assay method, iv injection into rabbits, a preparation of crude rabbit EP was titrated by both methods. The rat icv injcetion procedure gave results simil in linearity and magnitude of response to the conventional rabbit iv method, but was found to be at least 50-fold more sensitive. The icv assay worked for human as well as rabbit EP and for partially...
Topics: DTIC Archive, Critz, Walter J, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Intracerebroventricular (icv) injection of endogenous pyrogen (EP) into rats causes dose-related fever. To compare this procedure with the usual assay method, iv injection into rabbits, a preparation of crude rabbit EP was titrated by both methods. The rat icv injcetion procedure gave results simil in linearity and magnitude of response to the conventional rabbit iv method, but was found to be at least 50-fold more sensitive. The icv assay worked for human as well as rabbit EP and for partially...
Topics: DTIC Archive, Critz, Walter J, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Defense Technical Information Archive
texts
eye 0
favorite 0
comment 0
This award seeks to develop high-throughput optical metabolic imaging (OMI) of primary breast tumor organoids (three-dimensional cultures of tumors) to rapidly test/screen breast cancer therapeutics as a strategy to streamline drug development and provide individualized treatment. The results outlined in this progress report indicate that OMI in primary breast tumor organoids can provide early, sensitive measures of treatment response. This system can thereforebe used to streamline pre-clinical...
Topics: DTIC Archive, Skala,Melissa C, Vanderbilt University Nashville United States, BREAST CANCER,...
Intracerebroventricular (icv) injection of endogenous pyrogen (EP) into rats causes dose-related fever. To compare this procedure with the usual assay method, iv injection into rabbits, a preparation of crude rabbit EP was titrated by both methods. The rat icv injcetion procedure gave results simil in linearity and magnitude of response to the conventional rabbit iv method, but was found to be at least 50-fold more sensitive. The icv assay worked for human as well as rabbit EP and for partially...
Topics: DTIC Archive, Critz, Walter J, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Intracerebroventricular (icv) injection of endogenous pyrogen (EP) into rats causes dose-related fever. To compare this procedure with the usual assay method, iv injection into rabbits, a preparation of crude rabbit EP was titrated by both methods. The rat icv injcetion procedure gave results simil in linearity and magnitude of response to the conventional rabbit iv method, but was found to be at least 50-fold more sensitive. The icv assay worked for human as well as rabbit EP and for partially...
Topics: DTIC Archive, Critz, Walter J, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Breast cancers diagnosed up to six years after a completed pregnancy have been referred to as pregnancy-associated breast cancer or PABC. Several studies show that PABC frequently metastasizes, resulting in poor prognosis for the patient. Post-partum mammary gland involution is a necessary physiologic process required to return the lactation-competent gland to a non-lactating state. Accumulating evidence indicates that tissue-remodeling programs similar to wound healing are utilized to remodel...
Topics: DTIC Archive, Borges,Virginia F, The Regents of the University of Colorado Aurora United States
Intracerebroventricular (icv) injection of endogenous pyrogen (EP) into rats causes dose-related fever. To compare this procedure with the usual assay method, iv injection into rabbits, a preparation of crude rabbit EP was titrated by both methods. The rat icv injcetion procedure gave results simil in linearity and magnitude of response to the conventional rabbit iv method, but was found to be at least 50-fold more sensitive. The icv assay worked for human as well as rabbit EP and for partially...
Topics: DTIC Archive, Critz, Walter J, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Successful approaches to cancer immunotherapy require an understanding of the immune components in the microenvironment that enhance or inhibit tumor development and growth. Evidence is mounting that distinct T cell subsets contribute in positive or negative ways to these processes. An emerging area of interest relates to mechanisms by which sensing of metabolic cues regulates T cell fate and the character of the immune response. Our recent research suggested that an important metabolic...
Topics: DTIC Archive, Pan,Fan, JOHNS HOPKINS UNIV BALTIMORE MD BALTIMORE United States, TISSUE CULTURE...
Intracerebroventricular (icv) injection of endogenous pyrogen (EP) into rats causes dose-related fever. To compare this procedure with the usual assay method, iv injection into rabbits, a preparation of crude rabbit EP was titrated by both methods. The rat icv injcetion procedure gave results simil in linearity and magnitude of response to the conventional rabbit iv method, but was found to be at least 50-fold more sensitive. The icv assay worked for human as well as rabbit EP and for partially...
Topics: DTIC Archive, Critz, Walter J, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Intracerebroventricular (icv) injection of endogenous pyrogen (EP) into rats causes dose-related fever. To compare this procedure with the usual assay method, iv injection into rabbits, a preparation of crude rabbit EP was titrated by both methods. The rat icv injcetion procedure gave results simil in linearity and magnitude of response to the conventional rabbit iv method, but was found to be at least 50-fold more sensitive. The icv assay worked for human as well as rabbit EP and for partially...
Topics: DTIC Archive, Critz, Walter J, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Intracerebroventricular (icv) injection of endogenous pyrogen (EP) into rats causes dose-related fever. To compare this procedure with the usual assay method, iv injection into rabbits, a preparation of crude rabbit EP was titrated by both methods. The rat icv injcetion procedure gave results simil in linearity and magnitude of response to the conventional rabbit iv method, but was found to be at least 50-fold more sensitive. The icv assay worked for human as well as rabbit EP and for partially...
Topics: DTIC Archive, Critz, Walter J, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Defense Technical Information Archive
texts
eye 0
favorite 0
comment 0
The protective efficacy of a killed, purified, phase I Coxiella burnetii vaccine was tested in cynomolgus monkeys. Monkeys vaccinated once with 30 micrograms of the antigen were challenged 6 or 12 months later with virulent phase I rickettsiae administered in small-particle aerosols. The vaccine provided only partial protection, since some of the challenged monkeys developed clinical signs of illness. However, the vaccinated animals did not develop pneumonia as determined by radiographic...
Topics: DTIC Archive, Kishimoto, R A, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Defense Technical Information Archive
texts
eye 0
favorite 0
comment 0
The protective efficacy of a killed, purified, phase I Coxiella burnetii vaccine was tested in cynomolgus monkeys. Monkeys vaccinated once with 30 micrograms of the antigen were challenged 6 or 12 months later with virulent phase I rickettsiae administered in small-particle aerosols. The vaccine provided only partial protection, since some of the challenged monkeys developed clinical signs of illness. However, the vaccinated animals did not develop pneumonia as determined by radiographic...
Topics: DTIC Archive, Kishimoto, R A, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...
Defense Technical Information Archive
texts
eye 0
favorite 0
comment 0
The protective efficacy of a killed, purified, phase I Coxiella burnetii vaccine was tested in cynomolgus monkeys. Monkeys vaccinated once with 30 micrograms of the antigen were challenged 6 or 12 months later with virulent phase I rickettsiae administered in small-particle aerosols. The vaccine provided only partial protection, since some of the challenged monkeys developed clinical signs of illness. However, the vaccinated animals did not develop pneumonia as determined by radiographic...
Topics: DTIC Archive, Kishimoto, R A, ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD,...