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This article is from Journal of Epidemiology and Community Health , volume 65 . Abstract Background: A/H1N1, more commonly referred to as swine flu, emerged in Mexico in spring 2009. It rapidly spread across the world and was classed as a global pandemic on 11 June 2009. Objective: To analyse UK newsprint coverage of the swine flu pandemic. Methods: Content analysis of 2374 newsprint articles published in eight UK national newspapers between 1 March 2009 and 28 February 2010. Results: Newsprint...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171979
PubMed Central
by Hoy, C. L.; Gamm, U. A.; Sterenborg, H. J. C. M.; Robinson, D. J.; Amelink, A.
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This article is from Biomedical Optics Express , volume 3 . Abstract Multi-diameter single fiber reflectance (MDSFR) spectroscopy enables quantitative measurement of tissue optical properties, including the reduced scattering coefficient and the phase function parameter γ. However, the accuracy and speed of the procedure are currently limited by the need for co-localized measurements using multiple fiber optic probes with different fiber diameters. This study demonstrates the use of a coherent...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469986
PubMed Central
by Libiakova, Michaela; Flokova, Kristyna; Novak, Ondrej; Slovakova, L'udmila; Pavlovic, Andrej
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This article is from PLoS ONE , volume 9 . Abstract The trap of the carnivorous plant Venus flytrap (Dionaea muscipula) catches prey by very rapid closure of its modified leaves. After the rapid closure secures the prey, repeated mechanical stimulation of trigger hairs by struggling prey and the generation of action potentials (APs) result in secretion of digestive fluid. Once the prey's movement stops, the secretion is maintained by chemical stimuli released from digested prey. We investigated...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143254
PubMed Central
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This article is from Annals of The Royal College of Surgeons of England , volume 94 . Abstract INTRODUCTION: The preliminary results of a pyrocarbon interpositional radiocarpal implant in a small cohort of patients were reviewed. As it is currently only a limited release product, we describe to potential users early complications and negative outcomes. METHODS: Patients were assessed using pain levels, ranges of motion, grip strength, type of and time to return to work as well as pre-operative...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954246
PubMed Central
by Dalfardi, Behnam; Esnaashary, Mohammad Hosein; Yarmohammadi, Hassan
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This article is from Infectious Diseases of Poverty , volume 3 . Abstract Ibn Sina (980–1037 AD), known by his full name Abu Ali al-Hussain ibn Abdallah ibn Sina and the Latin name ‘Avicenna’, was a Persian scholar who is primarily remembered for his contributions to the science of medicine. He authored Al-Qanun fi al-Tibb (The Canon of Medicine). Sections of his work are devoted to detailed descriptions of a number of infectious illnesses, particularly rabies. Avicenna described rabies...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933285
This article is from Dialogues in Clinical Neuroscience , volume 9 . Abstract Evidence suggests that depression in multiple sclerosis (MS) is largely biologically mediated by some of the same processes involved in the immunopathogenesis of this neurologic disease. In particular, the increase in proinflammatory cytokines, activation of the hypothalamic-pituitary-adrenal (HPA) axis, and reduction in neurotrophic factors that occur in MS may each account for the increased rate of depression seen...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181849
PubMed Central
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This article is from PLoS ONE , volume 9 . Abstract Germline and somatic biallelic mutations of the Tuberous sclerosis complex (TSC) 1 and TSC2 gene products cause TSC, an autosomal dominant multifocal hamartomatosis with variable neurological manifestations. The consequences of TSC1 or TSC2 loss in cells of hematopoietic origin have recently started to be unveiled in mice and showed to hinder the development of proper T cell immunity. To date, the consequences of germline TSC1 mutations and/or...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954840
PubMed Central
by Tatsuke, Tsuneyuki; Zhu, Li; Li, Zhiqing; Mitsunobu, Hitoshi; Yoshimura, Kaito; Mon, Hiroaki; Lee, Jae Man; Kusakabe, Takahiro
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This article is from PLoS ONE , volume 9 . Abstract Piwi proteins are part of a superfamily of Argonaute proteins, which are one of the core components of the RNA silencing pathway in many eukaryotes. Piwi proteins are thought to repress the transposon expression both transcriptionally and post-transcriptionally. Recently, Drosophila melanogaster Piwi was recently reported to associate with chromatin and to interact directly with the Heterochromatin Protein 1 (HP1a). However, similar...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956929
PubMed Central
by Ghoorah, Anisah W.; Devignes, Marie-Dominique; Smail-Tabbone, Malika; Ritchie, David W.
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This article is from Nucleic Acids Research , volume 42 . Abstract Comparing, classifying and modelling protein structural interactions can enrich our understanding of many biomolecular processes. This contribution describes Kbdock (http://kbdock.loria.fr/), a database system that combines the Pfam domain classification with coordinate data from the PDB to analyse and model 3D domain–domain interactions (DDIs). Kbdock can be queried using Pfam domain identifiers, protein sequences or 3D...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964971
PubMed Central
by Mora-Lee, Silvia; Sirerol-Piquer, Ma Salome; Gutierrez-Perez, Maria; Lopez, Tania; Casado-Nieto, Mayte; Jauquicoam, Carlos; Abizanda, Gloria; Romaguera-Ros, Miriam; Gomez-Pinedo, Ulises; Prosper, Felipe; Garcia-Verdugo, Jose-Manuel
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This article is from Journal of Inflammation (London, England) , volume 8 . Abstract Background: Stroke models are essential tools in experimental stroke. Although several models of stroke have been developed in a variety of animals, with the development of transgenic mice there is the need to develop a reliable and reproducible stroke model in mice, which mimics as close as possible human stroke. Methods: BALB/Ca-RAG2-/-γc-/- mice were subjected to cauterization or thrombosis stroke model and...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221623
PubMed Central
by Yanardag, Halil; Tetikkurt, Cuneyt; Bilir, Muammer; Demirci, Sabriye; Iscimen, Aydin
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This article is from Multidisciplinary Respiratory Medicine , volume 8 . Abstract Background: Sarcoidosis is a systemic disease characterized by the formation of noncaseating granulomas in various tissues. Cutaneous involvement occurs in 20 to 35 percent of the patients and may be the initial manifestation of the disease. Our study was performed to discriminate the clinical, laboratory, and prognostic differences between patients with specific and nonspecific cutaneous involvement. The second...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614473
PubMed Central
by Tang, Mengjie; Tian, Yihao; Li, Doulin; Lv, Jiawei; Li, Qun; Kuang, Changchun; Hu, Pengchao; Wang, Ying; Wang, Jing; Su, Ke; Wei, Lei
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This article is from PLoS ONE , volume 9 . Abstract Acute lung injury (ALI) is an inflammatory disorder associated with reduced alveolar-capillary barrier function and increased pulmonary vascular permeability. Vasodilator-stimulated phosphoprotein (VASP) is widely associated with all types of modulations of cytoskeleton rearrangement-dependent cellular morphology and function, such as adhesion, shrinkage, and permeability. The present studies were conducted to investigate the effects and...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106849
PubMed Central
by Gliga, Anda R; Skoglund, Sara; Odnevall Wallinder, Inger; Fadeel, Bengt; Karlsson, Hanna L
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This article is from Particle and Fibre Toxicology , volume 11 . Abstract Background: Silver nanoparticles (AgNPs) are currently one of the most manufactured nanomaterials. A wide range of toxicity studies have been performed on various AgNPs, but these studies report a high variation in toxicity and often lack proper particle characterization. The aim of this study was to investigate size- and coating-dependent toxicity of thoroughly characterized AgNPs following exposure of human lung cells...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933429
PubMed Central
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This article is from Dialogues in Clinical Neuroscience , volume 11 . Abstract More than 25 million people in the world today are affected by dementia, most suffering from Alzheimer's disease. In both developed and developing nations, Alzheimer's disease has had tremendous impact on the affected individuals, caregivers, and society. The etiological factors, other than older age and genetic susceptibility, remain to be determined. Nevertheless, increasing evidence strongly points to the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181909
PubMed Central
by Ferreira, Amanda Ribeiro; Singh, Balwan; Cabrera-Mora, Monica; Magri De Souza, Alana Cristina; Queiroz Marques, Maria Teresa; Porto, Luis Cristovao Sobrino; Santos, Fatima; Banic, Dalma Maria; Calvo-Calle, J. Mauricio; Oliveira-Ferreira, Joseli; Moreno, Alberto; Da Costa Lima-Junior, Josue
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This article is from PLoS ONE , volume 9 . Abstract The development of modular constructs that include antigenic regions targeted by protective immune responses is an attractive approach for subunit vaccine development. However, a main concern of using these vaccine platforms is how to preserve the antigenic identity of conformational B cell epitopes. In the present study we evaluated naturally acquired antibody responses to a chimeric protein engineered to contain a previously defined...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141821
PubMed Central
by Rowles, Thomas A
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This article is from BMC Surgery , volume 14 . Abstract Contributing reviewers: The editors of BMC Surgery would like to thank all our reviewers who have contributed their time to the journal in Volume 13 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893518
PubMed Central
by Solera, Dafne
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This article is from BMC Cancer , volume 14 . Abstract Contributing reviewers: The editors of BMC Cancer would like to thank all our reviewers who have contributed to the journal in Volume 13 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909450
PubMed Central
by Shaffer, John R.; Polk, Deborah E.; Wang, Xiaojing; Feingold, Eleanor; Weeks, Daniel E.; Lee, Myoung-Keun; Cuenco, Karen T.; Weyant, Robert J.; Crout, Richard J.; McNeil, Daniel W.; Marazita, Mary L.
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This article is from G3: Genes|Genomes|Genetics , volume 4 . Abstract The etiology of chronic periodontitis clearly includes a heritable component. Our purpose was to perform a small exploratory genome-wide association study in adults ages 18–49 years to nominate genes associated with periodontal disease−related phenotypes for future consideration. Full-mouth periodontal pocket depth probing was performed on participants (N = 673), with affected status defined as two or more sextants with...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931564
PubMed Central
by Apratto Junior, Paulo Cavalcante; Barros, Monica Bastos de Lima; Daumas, Regina Paiva; Andrade, Monica Kramer de Noronha; Monteiro, Denise Leite Maia; Vincent, Beatriz Rodrigues Lopes; Lino, Valeria Teresa Saraiva; Rodrigues, Nadia Cristina Pinheiro
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This article is from International Journal of Environmental Research and Public Health , volume 11 . Abstract Objective: The aim of this study was to investigate the effects of three temporal components of AIDS incidence (i.e., age, period and cohort) on individuals aged 50 or older living in Niteroi, Rio de Janeiro (Brazil). Methods: Age-specific incidence rates were calculated from 1982–2011. Negative binomial and Poisson models were used to analyze the risk of AIDS by age, period and...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143821
PubMed Central
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This article is from Central European Journal of Urology , volume 64 . Abstract We report a rare case of a patient presenting with scrotal hematoma associated with retroperitoneal hemorrhage after extracorporeal shock wave lithotripsy (ESWL). We propose a mechanism for the formation of scrotal hematoma and its importance as a sign of retroperitoneal hemorrhage.
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921738
PubMed Central
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This article is from Acta Crystallographica Section E: Structure Reports Online , volume 67 . Abstract In the title compound, [Zn(C8H6N5O4)2(H2O)2], the six-coordinate ZnII ion, which is located on an inversion center, has a distorted octa­hedral configuration. Each 5-carb­oxy-2-[(1H-1,2,4-triazol-1-yl)meth­yl]-1H-imidazole-4-carboxyl­ate ligand chelates to the ZnII ion through a triazole N atom and a carboxyl­ate O atom in the equatorial plane. The coordination sphere is completed by two...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238584
PubMed Central
by Arensburger, Peter; Hice, Robert H; Wright, Jennifer A; Craig, Nancy L; Atkinson, Peter W
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This article is from BMC Genomics , volume 12 . Abstract Background: The piRNA pathway has been shown in model organisms to be involved in silencing of transposons thereby providing genome stability. In D. melanogaster the majority of piRNAs map to these sequences. The medically important mosquito species Aedes aegypti has a large genome size, a high transposon load which includes Miniature Inverted repeat Transposable Elements (MITES) and an expansion of the piRNA biogenesis genes. Studies of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259105
PubMed Central
by Volgyi, Eszter; Carroll, Kecia N.; Hare, Marion E.; Ringwald-Smith, Karen; Piyathilake, Chandrika; Yoo, Wonsuk; Tylavsky, Frances A.
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This article is from Nutrients , volume 5 . Abstract Dietary patterns are sensitive to differences across socio-economic strata or cultural habits and may impact programing of diseases in later life. The purpose of this study was to identify distinct dietary patterns during pregnancy in the Mid-South using factor analysis. Furthermore, we aimed to analyze the differences in the food groups and in macro- and micronutrients among the different food patterns. The study was a cross-sectional...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708333
PubMed Central
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This article is from Frontiers in Psychology , volume 5 . Abstract Recent research with moral dilemmas supports dual-process model of moral decision making. This model posits two different paths via which people can endorse utilitarian solution that requires personally harming someone in order to achieve the greater good (e.g., killing one to save five people): (i) weakened emotional aversion to the prospect of harming someone due to reduced empathic concern for the victim; (ii) enhanced...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033264
PubMed Central
by Hage, Eveline; Roo, John P; van Offenbeek, Marjolein AG; Boonstra, Albert
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This article is from BMC Health Services Research , volume 13 . Abstract Background: An ageing population is seen as a threat to the quality of life and health in rural communities, and it is often assumed that e-Health services can address this issue. As successful e-Health implementation in organizations has proven difficult, this systematic literature review considers whether this is so for rural communities. This review identifies the critical implementation factors and, following the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575225
PubMed Central
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This article is from Colombia Médica : CM , volume 43 . Abstract Objectives:: To describe the changes that occurred in some patterns of socio-demographic variables and in living conditions among the Nasa, Guambiana and Afrocolombian populations in the northern region of the Department of Cauca, and those occurring in two residential communities, one white-mestizo and one black, in Cali during the 1993-2005 period. Methods:: This paper presents a descriptive study that analyzes several...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001941
This article is from BMC Pediatrics , volume 12 . Abstract Background: The new growth charts in the UK, the UK-WHO charts, comprise prescriptive data from the WHO standard between two weeks and four years of age. Little is known about the development of obesity risk in normal UK infants, who are necessarily not fed according to the WHO recommendations and do not live in constraint-free environments (the selection criteria of the WHO standard source sample), using the new charts. Here, we...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439315
PubMed Central
by ALTOMARE, Roberta; CACCIABAUDO, Francesco; DAMIANO, Giuseppe; PALUMBO, Vincenzo Davide; GIOVIALE, Maria Concetta; BELLAVIA, Maurizio; TOMASELLO, Giovanni; LO MONTE, Attilio Ignazio
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This article is from Iranian Journal of Public Health , volume 42 . Abstract The Mediterranean tradition offers a cousine rich in colors, aromas and memories, which support the taste and the spirit of those who live in harmony with nature. Everyone is talking about the Mediterranean diet, but few are those who do it properly, thus generating a lot of confusion in the reader. And so for some it coincides with the pizza, others identified it with the noodles with meat sauce, in a mixture of...
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Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684452
PubMed Central
by Kourkouta, Lambrini; Papathanasiou, Ioanna V.
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This article is from Materia Socio-Medica , volume 26 . Abstract Good communication between nurses and patients is essential for the successful outcome of individualized nursing care of each patient. To achieve this, however, nurses must understand and help their patients, demonstrating courtesy, kindness and sincerity. Also they should devote time to the patient to communicate with the necessary confidentiality, and must not forget that this communication includes persons who surround the sick...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990376
PubMed Central
by Thijssen, Dick H. J.; Cable, N. Timothy; Green, Daniel J.
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This article is from Clinical Science (London, England : 1979) , volume 122 . Abstract Thickening of the carotid artery wall has been adopted as a surrogate marker of pre-clinical atherosclerosis, which is strongly related to increased cardiovascular risk. The cardioprotective effects of exercise training, including direct effects on vascular function and lumen dimension, have been consistently reported in asymptomatic subjects and those with cardiovascular risk factors and diseases. In the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233305
PubMed Central
by Cleutjens, Fiona A H M; Wouters, Emiel F M; Dijkstra, Jeanette B; Spruit, Martijn A; Franssen, Frits M E; Vanfleteren, Lowie E G W; Ponds, Rudolf W H M; Janssen, Daisy J A
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This article is from BMJ Open , volume 4 . Abstract Introduction: Intact cognitive functioning is necessary for patients with chronic obstructive pulmonary disease (COPD) to understand the value of healthy lifestyle guidelines, to make informed decisions and subsequently act on it. Nevertheless, brain abnormalities and cognitive impairment have been found in patients with COPD. To date, it remains unknown which cognitive domains are affected and what the possible consequences are of cognitive...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948451
PubMed Central
by Byrd, Allyson L; Perez-Rogers, Joseph F; Manimaran, Solaiappan; Castro-Nallar, Eduardo; Toma, Ian; McCaffrey, Tim; Siegel, Marc; Benson, Gary; Crandall, Keith A; Johnson, William Evan
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This article is from BMC Bioinformatics , volume 15 . Abstract Background: The use of sequencing technologies to investigate the microbiome of a sample can positively impact patient healthcare by providing therapeutic targets for personalized disease treatment. However, these samples contain genomic sequences from various sources that complicate the identification of pathogens. Results: Here we present Clinical PathoScope, a pipeline to rapidly and accurately remove host contamination, isolate...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131054
PubMed Central
by Schopf, Veronika; Fischmeister, Florian Ph. S.; Windischberger, Christian; Gerstl, Florian; Wolzt, Michael; Karlsson, Karl AE.; Moser, Ewald
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This article is from Frontiers in Human Neuroscience , volume 7 . Abstract This study aimed to directly assess the effect of changes in blood glucose levels on the psychological processing of emotionally charged material. We used functional magnetic resonance imaging (fMRI) to evaluate the effect of blood glucose levels on three categories of visually presented emotional stimuli. Seventeen healthy young subjects participated in this study (eight females; nine males; body weight, 69.3 ± 14.9...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659280
PubMed Central
by Neuba, Adam; Florke, Ulrich; Henkel, Gerald
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This article is from Acta Crystallographica Section E: Structure Reports Online , volume 68 . Abstract The mol­ecular structure of the title compound, [Cu(C11H16N3O3S)2], shows the CuII atom with a distorted square-planar coordination geometry from the N2O2 donor set of the two chelating 2-{[bis­(dimethyl­amino)­methyl­idene]amino}­benzene­sulfonate ligands. The CuII atom lies 0.065 (1) Å above the N2O2 plane and the Cu—O [2 × 1.945 (2) Å] and Cu—N bond lengths...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588740
PubMed Central
by Campion, Alicia; Casey, Pat G; Field, Des; Cotter, Paul D; Hill, Colin; Ross, R Paul
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This article is from BMC Microbiology , volume 13 . Abstract Background: Lantibiotics are post-translationally modified antimicrobial peptides, of which nisin A is the most extensively studied example. Bioengineering of nisin A has resulted in the generation of derivatives with increased in vitro potency against Gram-positive bacteria. Of these, nisin V (containing a Met21Val change) is noteworthy by virtue of exhibiting enhanced antimicrobial efficacy against a wide range of clinical and...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616995
PubMed Central
by Dreos, Rene; Ambrosini, Giovanna; Cavin Perier, Rouayda; Bucher, Philipp
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This article is from Nucleic Acids Research , volume 41 . Abstract The Eukaryotic Promoter Database (EPD), available online at http://epd.vital-it.ch, is a collection of experimentally defined eukaryotic POL II promoters which has been maintained for more than 25 years. A promoter is represented by a single position in the genome, typically the major transcription start site (TSS). EPD primarily serves biologists interested in analysing the motif content, chromatin structure or DNA methylation...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531148
PubMed Central
by Spolverato, Gaya; Pucciarelli, Salvatore; Bertorelle, Roberta; De Rossi, Anita; Nitti, Donato
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This article is from Cancers , volume 3 . Abstract Locally advanced rectal cancer is currently treated with pre-operative radiochemotherapy (pRCT), but the response is not uniform. Identification of patients with higher likelihood of responding to pRCT is clinically relevant, as patients with resistant tumors could be spared exposure to radiation or DNA-damaging drugs that are associated with adverse side effects. To highlight predictive biomarkers of response to pRCT, a systematic search of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757411
PubMed Central
by Deramaudt, Therese B.; Dujardin, Denis; Noulet, Fanny; Martin, Sophie; Vauchelles, Romain; Takeda, Ken; Ronde, Philippe
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This article is from PLoS ONE , volume 9 . Abstract Focal adhesion kinase (FAK) plays an important role in signal transduction pathways initiated at sites of integrin-mediated cell adhesion to the extracellular matrix. Thus, FAK is involved in many aspects of the metastatic process including adhesion, migration and invasion. Recently, several small molecule inhibitors which target FAK catalytic activity have been developed by pharmaceutical companies. The current study was aimed at addressing...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958421
PubMed Central
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This article is from BMC Public Health , volume 14 . Abstract Background: Premarital medical examination (PME) compliance rate has dropped drastically since it became voluntary in China in 2003. This study aimed to establish a prediction model to be a theoretic framework for analyzing factors affecting PME compliance in Zhejiang province, China. Methods: A culturally-tailored health behavioral model combining the Health Behavioral Model (HBM) and the Theory of Reasoned Action (TRA) was...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094453
PubMed Central
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This article is from Pediatric Gastroenterology, Hepatology & Nutrition , volume 16 . Abstract Purpose: The aim of this study was to compare the efficacy and safety of band ligation and injection sclerotherapy in the endoscopic treatment of children with variceal bleeding. Methods: The study population included 55 children, all of whom were treated at the time of endoscopic diagnosis of esophageal varices at Asan Medical Center, Seoul, Korea, between January 1994 and January 2011. The...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915733
PubMed Central
by Kikuchi, Y; Kume, A; Urabe, M; Mizukami, H; Suzuki, T; Ozaki, K; Nagai, T; Ozawa, K
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This article is from Journal of Stem Cells & Regenerative Medicine , volume 7 . Abstract Although mesenchymal stem cells (MSCs) play pivotal supportive roles in hematopoiesis, how they interact with hematopoietic stem cells (HSCs) is not well understood. We investigated the interaction between HSCs and surrogate MSCs (C3H10T1/2 stromal cells), focusing on the molecular events induced by cell contact of these bipartite populations. C3H10T1/2 is a mesenchymal stromal cell line that can be...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908275
PubMed Central
by Worku, Abebaw Gebeyehu; Yalew, Alemayehu Worku; Afework, Mesganaw Fantahun
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This article is from BMC International Health and Human Rights , volume 13 . Abstract Background: The evaluation of all potential sources of low skilled maternal care utilization is crucial for Ethiopia. Previous studies have largely disregarded the contribution of different levels. This study was planned to assess the effect of individual, communal, and health facility characteristics in the utilization of antenatal, delivery, and postnatal care by a skilled provider. Methods: A linked...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639034
PubMed Central
by Diler, Songul Budak; Ergene, Serap
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This article is from Genetics and Molecular Biology , volume 33 . Abstract The micronucleus (MN) assay on exfoliated buccal cells is a useful and minimally invasive method for monitoring genetic damage in humans. To determine the genotoxic effects of calcite dust that forms during processing, MN assay was carried out in exfoliated buccal cells of 50 (25 smokers and 25 non-smokers) calcite factory workers and 50 (25 smokers and 25 non-smokers) age- and sex-matched control subjects. Frequencies...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036877
PubMed Central
by Donga, Esther; van Dijk, Marieke; van Dijk, J. Gert; Biermasz, Nienke R.; Lammers, Gert-Jan; van Kralingen, Klaas; Hoogma, Roel P.L.M.; Corssmit, Eleonora P.M.; Romijn, Johannes A.
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This article is from Diabetes Care , volume 33 . Abstract OBJECTIVE: Sleep restriction results in decreased insulin sensitivity and glucose tolerance in healthy subjects. We hypothesized that sleep duration is also a determinant of insulin sensitivity in patients with type 1 diabetes. RESEARCH DESIGN AND METHODS: We studied seven patients (three men, four women) with type 1 diabetes: mean age 44 ± 7 years, BMI 23.5 ± 0.9 kg/m2, and A1C 7.6 ± 0.3%. They were studied once after a night of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890361
PubMed Central
by Sasaki, Tomohiko; Kunisaki, Reiko; Kinoshita, Hiroto; Kimura, Hideaki; Kodera, Teruaki; Nozawa, Akinori; Hanzawa, Akiho; Shibata, Naomi; Yonezawa, Hiromi; Miyajima, Eiji; Morita, Satoshi; Fujii, Shoichi; Numata, Kazushi; Tanaka, Katsuaki; Tanaka, Masanori; Maeda, Shin
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This article is from BMC Research Notes , volume 7 . Abstract Background: Crohn’s disease (CD) is routinely evaluated using clinical symptoms, laboratory variables, and the CD activity index (CDAI). However, clinical parameters are often nonspecific and do not precisely reflect the actual activity of CD small-intestinal lesions. The purposes of this prospective study were to compare color Doppler ultrasound (US) findings with histological findings from surgically resected specimens and...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080771
PubMed Central
by Pineda-Munoz, Silvia; Alroy, John
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This article is from Proceedings of the Royal Society B: Biological Sciences , volume 281 . Abstract Understanding the feeding behaviour of the species that make up any ecosystem is essential for designing further research. Mammals have been studied intensively, but the criteria used for classifying their diets are far from being standardized. We built a database summarizing the dietary preferences of terrestrial mammals using published data regarding their stomach contents. We performed...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100522
PubMed Central
by Moore, Lynette M.; Holmes, Kristen M.; Fuller, Gregory N.; Zhang, Wei
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This article is from Chinese Journal of Cancer , volume 30 . Abstract The aggressive and invasive nature of brain tumors has hampered progress in the design and implementation of efficacious therapies. The recent success of targeted therapies in other tumor types makes this an attractive area for research yet complicating matters is the ability of brain tumors to circumvent the targeted pathways to develop drug resistance. Effective therapies will likely need to target more than one signaling...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013312
PubMed Central
by Townsend, Ben; Abawajy, Jemal; Kim, Tai-Hoon
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This article is from Sensors (Basel, Switzerland) , volume 11 . Abstract People with special medical monitoring needs can, these days, be sent home and remotely monitored through the use of data logging medical sensors and a transmission base-station. While this can improve quality of life by allowing the patient to spend most of their time at home, most current technologies rely on hardwired landline technology or expensive mobile data transmissions to transmit data to a medical facility. The...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3231350
PubMed Central
by Zafar, Syed Nabeel; Khan, Muhammad Rizwan; Raza, Rushna; Khan, Muhammad N; Kasi, Mahwash; Rafiq, Ammar; Jamy, Omer H
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This article is from BMC Surgery , volume 11 . Abstract Background: Biliary-enteric anastomosis (BEA) is a common surgical procedure performed for the management of biliary obstruction or leakage that results from a variety of benign and malignant diseases. Complications following BEA are not rare. We aimed to determine the incidence and the factors associated with early complications occurring after BEA for benign diseases. Methods: We reviewed the medical records of all patients who underwent...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176468
This article is from International Journal of Circumpolar Health , volume 71 . Abstract Objectives: The Sami people constitute the indigenous people in northern Norway. The objective of this study was to clarify whether they have a similar supply of somatic specialist health care (SHC) as others. Methods: The referrals from general practitioners (GPs) in the primary health care (PHC) in the administration area of the Sami language law (8 municipalities) were matched with a control group of 11...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417552
PubMed Central
by Kitson, Alison; Powell, Kathryn; Hoon, Elizabeth; Newbury, Jonathan; Wilson, Anne; Beilby, Justin
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This article is from Implementation Science : IS , volume 8 . Abstract Background: Despite the considerable and growing body of knowledge translation (KT) literature, there are few methodologies sufficiently detailed to guide an integrated KT research approach for a population health study. This paper argues for a clearly articulated collaborative KT approach to be embedded within the research design from the outset. Discussion: Population health studies are complex in their own right, and...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674953
PubMed Central
by McHardy, Ian H; Li, Xiaoxiao; Tong, Maomeng; Ruegger, Paul; Jacobs, Jonathan; Borneman, James; Anton, Peter; Braun, Jonathan
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This article is from Microbiome , volume 1 . Abstract Background: Regardless of infection route, the intestine is the primary site for HIV-1 infection establishment and results in significant mucosal CD4+ T lymphocyte depletion, induces an inflammatory state that propagates viral dissemination, facilitates microbial translocation, and fosters establishment of one of the largest HIV reservoirs. Here we test the prediction that HIV infection modifies the composition and function of the mucosal...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971626
PubMed Central
by Rizvi, Narjis; S Khan, Kausar; Shaikh, Babar T
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This article is from BMC Women's Health , volume 14 . Abstract Background: Gender norms determine the status of Pakistani women that influence their life including health. In Pakistan, the relationship between gender norms and health of women is crucial yet complex demanding further analysis. This paper: determines the reasons for reiteration of gender roles; describes the societal processes and mechanisms that reproduce and reinforce them; and identifies their repercussions on women’s...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978051
PubMed Central
by Bonneh, Yoram S.; Donner, Tobias H.; Cooperman, Alexander; Heeger, David J.; Sagi, Dov
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This article is from PLoS ONE , volume 9 . Abstract Extended stabilization of gaze leads to disappearance of dim visual targets presented peripherally. This phenomenon, known as Troxler fading, is thought to result from neuronal adaptation. Intense targets also disappear intermittently when surrounded by a moving pattern (the “mask”), a phenomenon known as motion-induced blindness (MIB). The similar phenomenology and dynamics of these disappearances may suggest that also MIB is, likewise,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962462
PubMed Central
by Nick McElhinny, Stephanie A.; Becker, Jennifer J.
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This article is from Frontiers in Chemistry , volume 2 . Abstract None
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026725
PubMed Central
by Zhang, Li-li; Yang, Fang; Chang, Ting-min; Dong, Shu-ping; Fan, Ying-ying; Lu, Ting
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This article is from Pakistan Journal of Medical Sciences , volume 29 . Abstract Objective: We conducted a case-control study by genotyping three potential functional SNPs to assess the association of Xeroderma pigmentosum complementation group F (XPF) polymorphisms with gastric cancer susceptibility, and role of XPF polymorphisms in combination with H.pylori infection in the risk of gastric cancer.Methodology: A hospital case-control study was conducted. A total of 331 patients with gastric...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809291
PubMed Central
by Feng, Yiyu; Liu, Hongpo; Luo, Wen; Liu, Enzuo; Zhao, Naiqin; Yoshino, Katsumi; Feng, Wei
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This article is from Scientific Reports , volume 3 . Abstract Reduced graphene oxide-azobenzene (RGO-AZO) hybrids were prepared via covalent functionalization for long-term solar thermal storage. Thermal barrier (ΔEa) of cis to tran reversion and thermal storage (ΔH) were improved by molecular hydrogen bonds (H-bonds) through ortho- or para-substitution of AZO. Intramolecular H-bonds thermally stabilized cis-ortho-AZO on RGO with a long-term half-life of 5400 h (ΔEa = 1.2 eV), which was...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832871
PubMed Central
by Khan, Asim Ali; Jahangir, Umar; Urooj, Shaista
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This article is from Journal of Advanced Pharmaceutical Technology & Research , volume 4 . Abstract The study aimed to evaluate the effect of cupping therapy at a clinical setting for knee osteoarthritis. A randomized, controlled clinical trial was conducted. Cupping was performed on 0-6th day; 9-11th day and 14th day, i.e., 11 sittings follow-up to determine longer term carryover of treatment effects utilizing both objective and subjective assessment. The assessment was performed before...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853699
PubMed Central
by Hwang, Ara B; Jeong, Dae-Eun; Lee, Seung-Jae
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This article is from Current Genomics , volume 13 . Abstract Mitochondria are essential for various biological processes including cellular energy production. The oxidative stress theory of aging proposes that mitochondria play key roles in aging by generating reactive oxygen species (ROS), which indiscriminately damage macromolecules and lead to an age-dependent decline in biological function. However, recent studies show that increased levels of ROS or inhibition of mitochondrial function can...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468885
PubMed Central
by Furler, John; Hii, Justin W S; Liew, Danny; Blackberry, Irene; Best, James; Segal, Leonie; Young, Doris
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This article is from BMC Family Practice , volume 14 . Abstract Background: To describe the current treatment gap in management of cardiovascular risk factors in patients with poorly controlled type 2 diabetes in general practice as well as the associated financial and therapeutic burden of pharmacological treatment. Methods: Cross-sectional analysis of data from the Patient Engagement and Coaching for Health trial. This totalled 473 patients from 59 general practices with participants eligible...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599757
PubMed Central
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This article is from Theoretical Biology & Medical Modelling , volume 9 . Abstract Background: The H1N1 influenza A virus has been circulating in the human population for over 95 years, first manifesting itself in the pandemic of 1917–1918. Initial mortality was extremely high, but dropped exponentially over time. Influenza viruses have high mutation rates, and H1N1 has undergone significant genetic changes since 1918. The exact nature of H1N1 mutation accumulation over time has not been...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507676
This article is from International Journal of Systematic and Evolutionary Microbiology , volume 62 . Abstract Two novel obligately anaerobic, Gram-stain-positive, saccharolytic and non-proteolytic spore-forming bacilli (strains CD3 : 22T and N1T) are described. Strain CD3 : 22T was isolated from a biopsy of the small intestine of a child with coeliac disease, and strain N1T from the saliva of a healthy young man. The cells of both strains were observed to be filamentous, approximately 5...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541798
This article is from Frontiers in Endocrinology , volume 3 . Abstract This review provides a comprehensive overview of the vascularization of the avian growth plate and its subsequent role in the pathogenesis of bacterial chondronecrosis with osteomyelitis (BCO, femoral head necrosis). BCO sporadically causes high incidences of lameness in rapidly growing broiler (meat-type) chickens. BCO is believed to be initiated by micro-trauma to poorly mineralized columns of cartilage cells in the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3550519
This article is from Eplasty , volume 12 . Abstract Objective: Deliberate self-harm resulting in extensive skin scarring is a difficult clinical problem and is commonly associated with physical and sexual abuse or a known history of mental illness. Immediate hospital attendance often addresses the acute wound and current psychological state of patients; however, ongoing regret of these resulting scars present a problem to the patient and clinician. Deliberate self-harm to the skin leaves...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359068
This article is from Journal of Antimicrobial Chemotherapy , volume 67 . Abstract Objectives: Posaconazole is an extended-spectrum triazole with proven efficacy as antifungal treatment and prophylaxis. The marketed oral suspension should be taken with food to maximize systemic absorption. A new solid oral tablet has been developed with improved bioavailability that can be administered without regard to food. The aim of this study was to evaluate rising single- and multiple-dose...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468079
PubMed Central
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This article is from PhytoKeys . Abstract AbstractThe páramos and high Andean forests of the tropical Andes are largely dominated by frailejones (Nomen nudum Cuatrec., Nomen nudum). These plants are ecologically and culturally essential for both ecosystems and local inhabitants. The frailejones have been studied for over two centuries, but the taxonomic knowledge is still sparse and incomplete. The inedited monograph by Cuatrecasas contains only ca. 70% of the species known today, and...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492930
PubMed Central
by Zanini, Cristina; Gerbaudo, Elisa; Ercole, Elisabetta; Vendramin, Anna; Forni, Marco
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This article is from Environmental Health , volume 11 . Abstract Background: Formaldehyde (HCHO) is a gas (available as a 37% concentrated solution, stabilized with methanol). The 10% dilution (approximately 4% formaldehyde) has been used as a fixative since the end of the 19th century. Alternative fixatives are also commercially available or may be prepared in-house in laboratories. Statements by the IARC, along with other USA agencies (CalEPA, RoC/NTP) on the carcinogenicity of formaldehyde...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506558
PubMed Central
by Dialla, Pegdwende Olivia; Dabakuyo, Tienhan Sandrine; Marilier, Sophie; Gentil, Julie; Roignot, Patrick; Darut-Jouve, Ariane; Poillot, Marie-Laure; Quipourt, Valerie; Arveux, Patrick
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This article is from BMC Cancer , volume 12 . Abstract Background: A large proportion of women with breast cancer (BC) are elderly. However, there is a lack of information regarding BC prognostic factors and care in this population. The aims of this study were to assess the prognostic factors of relative survival (RS) among women with BC aged ≥ 75 years old and to identify the predictive factors of treatments administered to this population. Methods: A population-based study was performed...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517437
PubMed Central
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This article is from Experimental and Therapeutic Medicine , volume 8 . Abstract Chronic inflammation in the bronchi of long-term asthma patients worsens mood disorders, which has been shown to correlate with elevated levels of multiple proinflammatory cytokines. The glucocorticoid receptor (GR) gene, NR3C1, plays a key role in the control of inflammation. Disturbances in the structure and function of the GR alter the glucocorticoid regulation of the corticotropin-releasing hormone, which leads...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079411
PubMed Central
by Ali, Atif; Akhtar, Naveed; Chowdhary, Farzana
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This article is from Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii , volume 31 . Abstract Introduction: Solar ultraviolet exposure is the main cause of skin damage by initiation of reactive oxygen species (ROS) leading to skin collagen imperfection and eventually skin roughness. This can be reduced by proper revitalization of skin enhancing younger and healthier appearance. Aim: To evaluate the skin facial revitalization effect of a cream formulation containing the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112252
PubMed Central
by Van Parys, An-Sofie; Deschepper, Ellen; Michielsen, Kristien; Temmerman, Marleen; Verstraelen, Hans
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This article is from BMC Pregnancy and Childbirth , volume 14 . Abstract Background: Intimate partner violence (IPV) before and during pregnancy is associated with a broad range of adverse health outcomes. Describing the extent and the evolution of IPV is a crucial step in developing interventions to reduce the health impact of IPV.The objectives are to study the prevalence of psychological abuse, as well as physical & sexual violence, and to provide insight into the evolution of IPV...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159505
This article is from Oncology Letters , volume 5 . Abstract Laparoscopic partial gastrectomy without lymph node dissection has been accepted worldwide for the treatment of small gastric gastrointestinal stromal tumors (GISTs). However, the role of laparoscopic surgery in the treatment of large gastric GISTs remains under debate due to the risk of tumor spillage or rupture of the tumor capsule leading to peritoneal seeding. To the best of our knowledge, one-stage laparoscopic resection for a...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629169
PubMed Central
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This article is from Journal of Insect Science , volume 12 . Abstract The objective of the present study was to estimate the level of inbreeding coefficient during inbreeding of the pedigree of random mating and selected populations of two distinct races of mulberry silkworm, Bombyx mori (Lepidoptera: Bombycidae), in the silkworm germplasm. The six generation data of the two races, namely multivoltine Pure Mysore and bivoltine NB4D2, were studied for inbreeding depression coefficient using the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646607
PubMed Central
by Pafitis, Natalie
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This article is from BMC Public Health , volume 13 . Abstract Contributing reviewers: The editors of BMC Public Health would like to thank all our reviewers who have contributed to the journal in 2012.
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751667
PubMed Central
by Doroghazi, James R; Metcalf, William W
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This article is from BMC Genomics , volume 14 . Abstract Background: Actinomycetes are a diverse group of medically, industrially and ecologically important bacteria, studied as much for the diseases they cause as for the cures they hold. The genomes of actinomycetes revealed that these bacteria have a large number of natural product gene clusters, although many of these are difficult to tie to products in the laboratory. Large scale comparisons of these clusters are difficult to perform due to...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848822