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Full text of "USPTO Patents Application 09773351"

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PATENT ABSTRACTS OF JAPAN 



(1 1 )Publication number : 2001 -002551 

(43)Date of publication of application : 09.01 .2001 



(51)Int.CI. A61K 7/48 

A61K 7/00 



(21 jApplication number : 1 1-172415 (71)Applicant : KANEBO LTD 
(22)Date of filing : 1 8.06.1 999 (72)Inventor : SAKAI SHINGO 

SAYO TETSUYA 
YASUDA SUESHIGE 
INOUE SHINTARO 



(54) AGENT FOR INCREASING HYALURONIC ACID CONTENT OF HORNY LAYER 

(57)Abstract: 

PROBLEM TO BE SOLVED: To obtain the subject agent which can increase the 
hyaluronic acid content of the horny layer to optimize the water environment and 
hardness of the horny layer, allows to expect an effect for preventing rough skins and 
wrinkles, is stable in preparations, and is useful for skin cosmetics, by including 
N-acetylglucosamine. 

SOLUTION: This agent for increasing the hyaluronic acid content of a horny layer 
comprises N-acetylglucosamine. The agent is preferably added to a skin cosmetic 
preferably in an amount of 0.001 to 10%, especially preferably 0.01 to 5%, based on the 
total amount of the cosmetic composition. The agent may preferably further be 
compounded with a polyhydric alcohol such as 1 ,3-butylene glycol, a vitamin 
derivative such as an ascorbic acid phosphoric acid ester salt, an anionic surfactant 
such as N-stearoyl-L-glutamic acid salt, and so on. 



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