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PATENT 
Customer No. 22,852 



Attorney Docket No. 08702.0039-02000 
IN THE UNITED STATES PATENT AND TRADEMARK OFFICE 

In re Application of: ) 



Filed: March 9, 2001 

For: NOVEL BMP PRODUCTS 



Commissioner for Patents 

P.O. Box 1450 

Alexandria, VA 22313-1450 



SUPPLEMENTAL INFORMATION DISCLOSURE STATEMENT 
UNDER 37 C.F.R.S 1.97(c) 

Pursuant to 37 C.F.R. §§ 1 .56 and 1 .97(c), Applicants bring to the attention of the 
Examiner the documents on the attached listing. This Information Disclosure Statement 
is being filed after the events recited in Section 1 .97(b) but, to the undersigned's 
knowledge, before the mailing date of either a Final action, Quayle action, or a Notice of 
Allowance. Under the provisions of 37 C.F.R. § 1 .97(c), this Information Disclosure 
Statement is accompanied by a fee of $180.00 as specified by Section 1.17(p). 

Copies of the listed foreign and non-patent literature documents are attached. 
Copies of the U.S. patent publications are not enclosed. 

Applicants respectfully request that the Examiner consider the listed documents 
and indicate that they were considered by making appropriate notations on the attached 
form. 



Wang et al. 



Group Art Unit: 1647 



Application No.: 09/804,625 



Examiner: David S. Romeo 



Sir: 



PATENT 
Customer No. 22,852 
Attorney Docket No. 08702.0039-03000 

The following is a concise statement of relevance of the non-English language 

documents. 

1. JP63181770 discloses compositions comprising artificial bone cured and 
formed by mixing calcium triphosphate, acid, protein, and water. 

2. JP5277174 discloses methods for producing calcium phosphate and gelation 
bioimplantation materals. 

3. JP51-0233901A discloses bioimplantable compositions comprising calcium 
phosphates, carboxymethyl ketone, collagen, and gelatin. 

Applicants include these references because they were cited in other BMP 
applications assigned to Wyeth, Applicants' assignee. Applicants have not considered 
or characterized these references, but are simply submitting them for the Examiner's 
consideration. 

Applicants will continue to submit all documents that are material to patentability 
as they become aware of them. 

This submission does not represent that a search has been made or that no 
better art exists and does not constitute an admission that each or all of the listed 
documents are material or constitute "prior art." If the Examiner applies any of the 
documents as prior art against any claim in the application and Applicants determine 
that the cited documents do not constitute "prior art" under United States law, 
Applicants reserve the right to present to the Office the relevant facts and law regarding 
the appropriate status of such documents. 



-2- 



PATENT 
Customer No. 22,852 
Attorney Docket No. 08702.0039-03000 

Applicants further reserve the right to take appropriate action to establish the 
patentability of the disclosed invention over the listed documents, should one or more of 
the documents be applied against the claims of the present application. 

If there is any fee due in connection with the filing of this Statement, please 

charge the fee to Deposit Account No. 06-0916. 

Respectfully submitted, 

FINNEGAN, HENDERSON, FARABOW, 
GARRETT & DUNNER, LLP. 

Dated: ^jit)!^)^ 

Reg. No. 54,696 




-3- 



CERTIFICATE UNDER 37 CFR § 1 .10 OF 
'A MAILING BY "EXPRESS MAIL" 

EV 618618802 US 
EV 618318816 US 

EV 618318820 US March 30, 2005 



USPS Express Mail Label Number Date of Deposit 



I hereby certify that this correspondence is being deposited with the United States 
Postal Services "Express Mail Post Office to Addressee" service under 37 CFR § 1.10 
on the date indicated above and is addressed to the Commissioner for Patents, P.O. 
Box 1450, Alexandria, VA 22313-1450. ^ 

By: 44<^AhjiAcM^ 

Kathl^n M. Bastarache 




D/SB/08: Substitute for form 1449A/PTO 

RMATION DISCLOSURE 
TEMENT BY APPLICANT 

(Use as many sheets as necessary) 



1 



of 



18 



Complete if Known 



Application Number 



Filing Date 



First Named Inventor 



Art Unit 



Examiner Name 



Attorney Docket Number 



09/804.625 



March 9. 2001 



Wang 



1647 



D. Romeo 



08702.0039-02000 



U.S. PATENTS AND PUBLISHED U.S. PATENT APPLICATIONS 


Examiner 
Initials 


Cite 
No.^ 


Document Number 


Issue or 
Publication 
Date 
MIVI-DD-YYYY 


Name of Patentee or 
Applicant of Cited 
Document 


Pages, Columns, Lines, 

Where 
Relevant Passages or 
Relevant 

Finiirp*; Annpar 


Number-Kind 
Code^ (if known) 






2,465.357 


29 Mar 1949 


Correll et al. 








3,955,719 


11 May 1976 


Pheulpin 








4,191,747 A 


04 Mar 1980 


Scheicher 








4,294,753 


13 Oct 1981 


Urist 








4,394,370 


19 July 1983 


Jeffries 








4,399,216 


16 Aug 1983 


Axel et al. 








4.419,446 


06 Dec 1986 


Howley et al. 








4.434,094 


28 Feb 1984 


Seyedin et al. 








4.441.915 


10 Apr 1984 


Arndt et al. 








4.455.256 


19 Jun 1984 


Urist 








4.468.464 


28 Aug 1984 


Cohen et al. 








4,472.840 


25 Sept 1984 


Jefferies 








4,553,542 


19 Nov 1985 


Schenk et al. 








4,563,350 


07 Jan 1986 


Nathan et al. 








4,596.574 


24 June 1986 


Urist 








4,608.199 


26 Aug 1986 


Caplan et al. 








4,619.989 


28 Oct 1986 


Ufist 








4,627.982 


09 Dec 1986 


Seyedin et al. 








4,642,120 


10 Feb 1987 


Nevo et al. 








4,662,884 


05 May 1987 


Stenaas 








4,681,763 


21 Jul 1987 


Nathanson 








4,703.008 


27 Oct 1987 


Lin 








4,727,028 


23 Feb 1988 


Santerre et al. 








4,737,578 


12 Apr 1988 


Evans 








4,758,233 


19 Jul 1988 


Phillips et al. 








4,761,471 


2 Aug 1988 


Urist 








4,766.067 


23 Aug 1988 


Bisw/as et al. 








4,767.628 


30 Aug 1988 


Hutchinson 








4,769.328 


06 Sept 1988 


Murray et al. 








4,774.228 


27 Sept 1988 


Seyedin et al. 








4,774,322 


27 Sept 1988 


Seyedin et al. 








4,784.055 


15 Nov 1988 


Langen et al. 





IDS Form PTO/SB/08: Substitute for form 1449A/PTO 

INFORMATION DISCLOSURE 
STATEMENT BY APPLICANT 

(Use as many sheets as necessary) 


Complete if Known 


Application Number 


09/804.625 


Filing Date 


March 9. 2001 


First Named Inventor 


Wang 


Art Unit 


1647 


Examiner Name 


D. Romeo 


Sheet 1 2 of | 18 


Attorney Docket Number 


08702.0039-02000 



U.S. PATENTS AND PUBLISHED U.S. PATENT APPLICATIONS 







4,789,732 


06 Dec 1988 


Urist 








4,795,804 


30 Jan 1989 


Urist 








4,798,885 


17 Jan 1989 


Mason 








4,804,744 


14 Feb 1989 


Sen 








4,810,691 


07 Mar 1989 


Seyedin 








4,828,990 


09 May 1998 


Naoki et al. 








4,843,063 


27 Jun1989 


Seyedin 








4,851,521 


25 Jul 1989 


Delia Valle et al. 








4,868,161 


19 Sept 1989 


Roberts 








4,877,864 


31 Oct 1989 


Wang et al. 








4,886,747 


12 Dec 1989 


Derynck 








4,908,204 


13 Mar 1990 


Robinson et al. 








4,920,962 


1 May 1990 


Proulx 








4,923,805 


8 May 1990 


Reddy et al. 








4,955,892 


11 Sept 1990 


Daniloff et al. 








4,963,146 


16 Oct 1990 


Li 








4,968,590 


06 Nov 1990 


Kuberasampath et al. 








4,992,274 


12 Feb 1991 


Robinson et al. 








5,011,486 


30 Apr 1991 


Aebischer et al. 








5,011,691 


30 Apr 1991 


Oppermann 








5,013,649 


07 May 1991 


Wang et al. 








5,019,087 


28 May 1991 


Nichols 








5,024,841 


18 Jun 1991 


Chu et al. 








5,026.381 


25 Jun 1991 


Li 








5,041,538 


20 Aug 1991 


Ling et al. 








5,071,834 


10 Dec 1991 


Burton et al. 








5,089,396 


18 Feb 1992 


Mason et al. 








5,102,807 


07 Apr 1992 


Burger et al. 








5,106,626 


21 Apr 1992 


Parsons et al. 








5,106,748 


21 Apr 1992 


Wozney et al. 








5,108,753 


28 Apr 1992 


Kuberasampath 








5,108,922 


28 Apr 1992 


Wang et al. 








5,116,738 


26 May 1992 


Wang et al. 








5,118,667 


2 June 1992 


Adams et al. 








5,124,316 


23 Jun 1992 


Antoniades et al 








5,141,905 


25 Aug 1992 


Rosen et al. 





IDS Form PTO/SB/08: Substitute for form 1449A/PTO 

INFORMATION DISCLOSURE 
STATEMENT BY APPLICANT 

{Use as many sheets as necessary) 


Complete if Known 


Application Number 


09/804,625 


Filing Date 


March 9, 2001 


First Named Inventor 


Wang 


Art Unit 


1647 


Examiner Name 


D. Romeo 


Sheet 3 of 18 


Attorney Docket Number 


08702.0039-02000 



U.S. PATENTS AND PUBLISHED U.S. PATENT APPLICATIONS 






5,147.399 


15 Sept 1992 


Dellon et al. 








5,166.058 


24 Nov 1992 


Wang et al. 








5.166.190 


24 Nov 1992 


Mather et al. 








5.166.322 


24 Nov 1992 


Shaw/ et al. 








5.168.050 


01 Dec 1992 


Hammonds 








5.171,579 


15 Dec 1992 


Ron et al. 








5.187.076 


16 Feb 1993 


Wozney et al. 








5.187.263 


16 Feb 1993 


Murray et al. 








5.202.120 


13 Apr 1993 


Silver et al. 








5.206.028 


27 Apr 1993 


Li 








5,208.219 


04 May 1993 


Ogawa et al. 








5.215,893 


01 Jun 1993 


Mason et al. 








5.216,126 


01 Jun 1993 


Cox et al. 








5.217.867 


08 Jun 1993 


Evans et al. 








5,218.090 


08 Jun 1993 


Connors 








5.229,495 


20 July 1993 


Ichijo et al. 








5.256.418 


26 Oct 1993 


Kemp et al. 








5.258.494 


02 Nov 1993 


Oppermann et al. 








5,266,683 


30 Nov 1993 


Oppermann et al. 








5.278.145 


11 Jan 1994 


Keller et al. 








5,284.756 


08 Feb 1994 


Grinna et al. 








5,286.654 


15 Feb 1994 


Cox et al. 








5,290.271 


01 Mar 1994 


Jernberg 








5.292.802 


08 Mar 1994 


Rhee et al. 








5.306.307 


26 Apr 1994 


Senter et al. 








5,308.889 


03 May 1994 


Rhee et al. 








5,324,519 


28 Jun 1994 


Dunn et al. 








5,324.775 


28 Jun 1994 


Rhee et al. 








5.328.955 


12 Jul 1994 


Rhee et al. 








5,352,715 


4 Oct 1997 


McMullln et al. 








5,354.557 


11 Oct 1994 


Oppermann et al. 








5,356,629 


18 Oct 1994 


Sander et al. 








5.364.839 


15 Nov 1994 


Gerhart et al. 








5,366,875 


22 Nov 1994 


Wozney et al. 








5,399.346 


21 Mar 1995 


Anderson et al. 








5.399.677 


21 Mar 1995 


Wolfman et al. 





IDS Form PTO/SB/08: Substitute for form 1449A/PTO 

INFORMATION DISCLOSURE 
STATEMENT BY APPLICANT 

(Use as many sheets as necessary) 


Complete if Known 


Application Number 


09/804,625 


Filing Date 


March 9, 2001 


First Named Inventor 


Wang 


Art Unit 


1647 


Examiner Name 


D. Romeo 


Sheet 4 of 18 


Attorney Docket Number 


08702.0039-02000 



U.S. PATENTS AND PUBLISHED U.S. PATENT APPLICATIONS 






5.405,390 


11 Apr 1995 


O'Leary et al. 








5,411,941 


02 May 1995 


Grinna et al. 








5,413,989 


09 May 1995 


Ogawa et al. 








5,420,243 


30 May 1995 


Ogawa et al. 








5,422,340 


06 Jun 1995 


Ammann et al. 








5,447,725 


05 Sept 1995 


Damlani et al. 








5,455,041 


03 Oct 1995 


Genco et al. 








5,455,329 


03 Oct 1995 


Wingender 








5,457,047 


10 Oct 1995 


Wingender 








5,457,092 


10 Oct 1995 


Schulter 








5,459.047 


17 Oct 1995 


Wozney et al. 








5,464,440 


07 Nov 1995 


Johannsson 








5.508,263 


16 Apr 1996 


Grinna et al. 








5,516,654 


14 May 1996 


Israel 








5.520,923 


28 May 1996 


Tjia etal. 








5.538,892 


23 Jul 1996 


Donahoe et al. 








5.543.394 


06 Aug 1996 


Wozney et al. 








5.545.616 


13 Aug 1996 


Woddruff 








5,547.854 


20 Aug 1996 


Donahoe et al. 








5.556,767 


17 Sept 1996 


Rosen et al. 








5,618.924 


08 Apr 1997 


Wang et al. 








5.631.142 


20 May 1997 


Wang et al. 








5,635.372 


3 Jun 1997 


Celeste et al. 








5,635.373 


03 Jun 1997 


Wozney et al. 








5,637.480 


10 Jun 1997 


Celeste et al. 








5,639.638 


17 Jun 1997 


Wozney et al. 








5,645.592 


08 Jul 1997 


Nicolais et al. 








5,648.467 


15 July 1997 


Kobayashi et al. 








5,650,494 


22 Jul 1997 


Cerletti et al. 








5,658,882 


19 Aug 1997 


Celeste et al. 








5,661,007 


26 Aug 1997 


Wozney et al. 








5,674.292 


07 Oct 1997 


Tucker et al. 








5,688,678 


8 Nov 1997 


Hewick et al. 








5,693,779 


02 Dec 1991 


Moos, Jr. et al. 








5,700,664 


23 Dec 1997 


Bennett 








5,700,774 


23 Deal 997 


Hattersley et al 





IDS Fonm PTO/SB/08: Substitute for fomn 1449A/PTO 

INFORMATION DISCLOSURE 
STATEMENT BY APPLICANT 

CL/se as many sheets as necessary) 


Complete if Known 


Application Number 


09/804,625 


Filing Date 


March 9, 2001 


First Named Inventor 


Wang 


Art Unit 


1647 


Examiner Name 


D. Romeo 


Sheet 5 of 18 


Attorney Docket Number 


08702.0039-02000 



U.S. PATENTS AND PUBLISHED U.S. PATENT APPLICATIONS 






5,700,911 


23 Dec 1997 


Wozney et al. 








5,703,043 


30 Dec 1997 


Celeste et al. 








5,728,679 


17 Mar 1998 


Celeste et al. 








5,750,651 


12 May 1998 


Opperman et al. 








5,752,974 


19 May 1998 


Rhee et al. 








5,756,457 


25 May 1998 


Wang et al. 








5,786,217 


28 Jul 1998 


Tubo et al. 








5,813,411 


29 Sept 1998 


Van Bladel etal. 








5,827,733 


27 Oct 1998 


Lee et al. 








5,846,931 


08 Dec 1998 


Hattersley et al. 








5,849,880 


15 Dec 1998 


Wozney et al. 








5,866,364 


02 Feb 1999 


Israel et al. 








5,932,216 


03 Aug 1999 


Celeste et al. 








5,935,594 


10 Aug 1999 


RIngelsen et al. 








5,936,067 


10 Aug 1999 


Graham et al. 








5,939,323 


17 Aug 1999 


Valentin! et al. 








5,939,388 


17 Aug 1999 


Rosen et al. 








5,965,403 


12 Oct 1999 


Celeste et al. 








5,972,368 


26 Oct 1996 


MacKay 








5,986,058 


16 Nov 1999 


Lee et al. 








6,001,352 


14 Dec 1999 


Boyan et al. 








6,004,937 


21 Dec 1999 


Wood et al. 








6,027,919 


22 Feb 2000 


Celeste et al. 








6,034,061 


06 Mar 2000 


Rosen et al. 








6,034,062 


07 Mar 2000 


Thies et al. 








6,132,214 


17 Oct 2000 


Sohonen et al. 








6,150,328 


21 Nov 2000 


Wang et al. 








6,177,406 


23 Jan 2001 


Wang et al. 








6,187,742 


13 Feb 2001 


Wozney et al. 








6,190,880 


20 Feb 2001 


Israel et al. 








6,207,813 


26 Mar 2001 


Wozney et al. 








6,245,889 


12 Jun 2001 


Wang et al. 








6,284,872 


04 Sep 2001 


Celeste et al. 








6,287,816 


11 Sep 2001 


Rosen et al. 








6,291,206 


18 Sep 2001 


Wozney et al. 








6,331,612 


18 Dec 2001 


Celeste et al. 





IDS Form PTO/SB/08: Substitute for form 1449A/PTO 

INFORMATION DISCLOSURE 
STATEMENT BY APPLICANT 

(Use as many sheets as necessary) 


Complete if Known 


Application Number 


09/804,625 


Filing Date 


March 9, 2001 


First Named Inventor 


Wang 


Art Unit 


1647 


Examiner Name 


D. Romeo 


Sheet 6 of 18 


Attorney Docket Number 


08702.0039-02000 



U.S. PATENTS AND PUBLISHED U.S. PATENT APPLICATIONS 






6,340,668 


22 Jan 2002 


Celeste et al. 








6,432,919 


13 Aug 2002 


Wang et al. 








6,437,111 


20 Aug 2002 


Wozney et al. 








6,558,925 


06 May 2003 


Graham et al. 








6,586,388 


01 Jul 2003 


Oppermann et al. 








6,593,109 


15 Jul 2003 


Israel et al. 








6,610,513 


26 Aug 2003 


Wozney et al. 








6,613,744 


02 Sep 2003 


Wozney et al. 








6,623,934 


23 Sep 2003 


Celeste et al. 








6,699,471 


02 Mar 2004 


Radici et al. 








6,719,968 


13 Apr 2004 


Celeste et al. 





Note: Copies of the U.S. Patent Documents are not Required in IDS filed after October 21, 2004 



FOREIGN PATENT DOCUMENTS 


Exami 

ner 
Initials 


Cite 
No/ 


Foreign Patent Document 


Publication 
Date 


Name of Patentee 
or 

Applicant of Cited 
Document 


Pages, Columns, 
Lines, Where 

Relevant 
Passages or 
Relevant Figures 
Appear 


Translati 
on^ 


Country Code^ Number^ Kind 
Code* {if known) 






BP 0 052 510 


26 May 1982 












EP 0 058 481 


25 Aug 1982 












EPO 121 976 


17 Oct 1984 












EPO 128 041 


12 Dec 1984 












EP 0 148 155 


10 Jul 1985 












EPO 155,476 


25 Sep 1985 












EPO 169 016 


01/1986 












EPO 177 343 


09 Apr 1986 












EPO 212 474 


04 Mar 1987 












EP 0 222 491 


02 Oct 1986 












EP 0 241 809 


21 Oct 1987 












EPO 313 578 


28 Aug 1996 












EP 0 329 239 


23 Aug 1989 












EP 0 336 760 


06 Apr 1989 












EPO 394 418 


13 Oct 1990 












EP 0 401 055 


05 Dec 1990u 












EP 0 409 472 


23 Jan 1991 












EPO 416 578 


13 Mar 1991 









IDS Form PTO/SB/08: Substitute for form 1449A/PTO 

INFORMATION DISCLOSURE 
STATEMENT BY APPLICANT 

(Use as many sheets as necessary) 


Complete if Known 


Application Number 


09/804.625 


Filing Date 


March 9, 2001 


First Named Inventor 


Wang 


Art Unit 


1647 


Examiner Name 


D. Romeo 


Sheet 7 of 18 


Attorney Docket Number 


08702.0039-02000 



FOREIGN PATENT DOCUMENTS 






BP 0 429 570 


05 Jun 1991 












BP 0 433 225 


19 Jun 1991 












BP 0 512 844 


11 Nov 1992 












BP 0 530 804 


10 Mar 1993 












BP 0 531 448 


17 Nov 1994 












BP 0 536 186 


21 Nov 2001 












BP 0 592 562 


07 Jan 1999 












BP 0 626 451 


30 Nov 1994 












BP 0 688 869 


27 Dec 1995 












BP 0 741 187 


06 Nov 1996 












BP 0 831 884 


21 May 1996 












BP 1 061 940 


24 Feb 1999 












WO 84/01 106 


29 Mar 1984 












WO 85/04173 


26 Sep 1985 












WO 86/00525 


30 Jan 1986 












WO 86/00639 


30 Jan 1986 












WO 87/00528 


29 Jan 1987 












WO 88/00205 


14 Jan 1988 












WO 89/09787 


19 Oct 1989 












WO 89/09788 


19 Oct 1989 












WO 89/10133 


02 Nov 1989 












WO 89/10409 


02 Nov 1989 












WO 90/03733 


19 Apr 1990 












WO 90/11366 


04 Oct 1990 












WO 91/02744 


07 Mar 1991 












WO 91/04274 


04 Apr 1991 












WO 91/05802 


02 May 1991 












WO 91/10444 


25 Jul 1991 












WO 91/17777 


28 Nov 1991 












WO 91/18047 


28 Nov 1991 












WO 91/18098 


28 Nov 1991 












WO 92/05198 


02 Apr 1992 












WO 92/05199 


02 Apr 1992 












WO 92/07004 


30 Apr 1992 












WO 92/07073 


30 Apr 1992 












WO 92/09697 


06 Nov 1992 









IDS Form PTO/SB/08: Substitute for form 1449A/PTO 

INFORMATION DISCLOSURE 
STATEMENT BY APPLICANT 

(Use as many sheets as necessary) 


Complete if Known 


Application Number 


09/804,625 


Filing Date 


March 9, 2001 


First Named Inventor 


Wang 


Art Unit 


1647 


Examiner Name 


D. Romeo 


Sheet 1 8 of | 18 


Attorney Docket Number 


08702.0039-02000 



FOREIGN PATENT DOCUMENTS 






WO 92/14481 


03 Sept 1992 












WO 92/15323 


17 Sep 1992 












WO 92/20793 


26 Nov 1992 












WO 92/22319 


23 Dec 1992 












WO 93/00049 


07 Jan 1993 












WO 93/00050 


07 Jan 1993 












WO 93/00432 


07 Jan 1993 












WO 93/04692 


18 Mar 1993 












WO 93/05751 


01 Apr 1993 












WO 93/06872 


15 Apr 1993 












WO 93/09228 


13 May 1993 












WO 93/09229 


13 May 1993 












WO 93/09802 


27 May 1993 












WO 93/13206 


08 Jul 1993 












WO 93/16099 


19 Aug 1993 












WO 93/19177 


30 Sep 1993 












WO 93/20858 


28 Oct 1993 












WO 94/01557 


20 Jan 1994 












WO 94/03200 


17 Feb 1994 












WO 94/06449 


31 Mar 1994 












WO 94/1 1502 


26 May 1994 












WO 94/15949 


21 Jul 1994 












WO 94/15965 


21 Jul 1994 












WO 94/15966 


21 Jul 1994 












WO 94/21681 


29 Sep 1994 












WO 94/24285 


27 Oct 1994 












WO 94/26892 


24 Nov 1994 












WO 94/26893 


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WO 95/05846 


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20 Apr 1995 












WO 95/12664 


11 May 1995 












WO 95/15966 


15 Jun 1995 









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PAJ 03-345189 


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Patent Abstracts of 
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Non-English: 

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NON PATENT LITERATURE DOCUMENTS 


Examiner 
iniiiais 


Cite 

INO. 


Include name of the author (in CAPITAL LETTERS), title of the article (when 
appropnaiej, iiiie or ine iiem (dook, magazine, journal, serial, symposium, 
catalog, etc.), date, page(s), volume-issue number(s), publisher, city and/or 

country where published. 


Translation® 






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IDS Form PTO/SB/08; Substitute for form 1449A/PTO 

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Sheet 11 of 18 


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NON PATENT LITERATURE DOCUMENTS 






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Sheet 12 of 18 


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NON PATENT LITERATURE DOCUMENTS 






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NON PATENT LITERATURE DOCUMENTS 






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NON PATENT LITERATURE DOCUMENTS 






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Sheet 15 of | 18 


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NGN PATENT LITERATURE DOCUMENTS 






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1647 


Examiner Name 


D. Romeo 


Sheet 16 of 18 


Attorney Docket Number 


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NON PATENT LITERATURE DOCUMENTS 






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Sheet 17 of 18 


Attorney Docket Number 


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NON PATENT LITERATURE DOCUMENTS 






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IDS Form PTO/SB/08; Substitute for form 1449A/PTO 

INFORMATION DISCLOSURE 
STATEMENT BY APPLICANT 

(Use as many sheets as necessary) 


Complete if Known 


Application Number 


09/804,625 


Filing Date 


March 9, 2001 


First Named Inventor 


Wang 


Art Unit 


1647 


Examiner Name 


D. Romeo 


Sheet 18 of 18 


Attorney Docket Number 


08702.0039-02000 



NON PATENT LITERATURE DOCUMENTS 






Yamaji et al., Biochem. Biophys. Res. Comm., 205:1944-1951 (1994) 








Zipfel et al.. J. Immunol., 142:1582 (1989) 








Zheng etal., Path. Res. Pract, 188:1104-1121 (1992) 








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