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Full text of "USPTO Patents Application 09804625"

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MAY-08-2006 18:03 From: FINNEGAN HENDERSON 6174521666 



To:USPTO 



P.4'7 



PATENT 
Customer No. 22,852 
Attorney Docket No. 08702.0039-02000 

AMENDMENTS TO THE CLAIMS: 

This listing of claims replaces all prior versions and listings of claims in this 
application: 

1-23. (Cancelled) 

24. (Previously presented) An isolated polynucleotide comprising: 

a) nucleotide 1 252 through 1 543 of Figure 2; or 

b) nucleotides encoding amino acids 299 through 396 of Figure 2. 

25. (Cancelled) 

26. (Previously presented) An isolated polynucleotide comprising nucleotides 
1252 through 1543 of Figure 2. 

27-29. (Cancelled) 

30. (Previously presented): An isolated polynucleotide comprising nucleotides 
encoding amino acids 299 through 396 of Figure 2. 
31-34. (Cancelled) 

35. (Currently amended) A vector comprising a polynucleotide of claim 24 in 
operative association with an expression control sequence therefore therefor . 
36-37. (Cancelled) 

38. (Previously presented) A host cell transformed with a vector of claim 35. 
39-40. (Cancelled) 

41 . (Currently amended) An isolated polynucleotide comprising nucleotides of 
ATCC deposit 40345. 

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MAY-&8-2006 18:03 From: FINNEGAN HENDERSON 6174521666 



To:USPTO 



P. 5'7 



PATENT 
Customer No. 22,852 
Attorney Docket No. 08702.0039-02000 

42. (Currently amended) A method for producing a bone morphogenetic 
protein, said method comprising the steps of: 

a) culturing a host cell transformed with a polynucleotide of claim43 claim 24 . 

and 

b) recovering said bone morphogenetic protein. 
43-49. (Cancelled) 

50. (New) An isolated bone morphogenetic protein, wherein said protein is 
produced by the method of claim 42. 

51 . (New) A BMP-2 made by the method of claim 42, 

52. (New) An isolated BMP-2 polypeptide comprising an amino acid 
sequence encoded by a polynucleotide of claim 26. 

53. (New) An isolated BMP-2 polypeptide comprising an amino acid 
sequence encoded by a polynucleotide of claim 30. 

54. (New) An isolated BMP-2 protein comprising an amino acid sequence of 
amino acid 299 through 396 of Figure 2. 



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