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Form PTO-1440 



U.S. OC^**TMCNT or COwmCACC 



INFORMATION DISCLOSURE STATEMENT 
BY APPLICANT 
(Use s**cr*l *A cef j if necossarr) 



*TTY. OOCACT „o. 

GI 5160C 



A**UCA*T 



SCMIAL MO. > ' 

*0J/7J.1. H7T~ 



B. Wang » r a1 



riLINC oats 

14 June 1991 



CAOOP 



1814 



U.S. PATENT DOCUMENTS 



OOCUUfMT NUMIIH 



OATt 



NAMC 



CLASS 



SUICLASS 




7 9 



2/14/89 



Sea 



9/27/88 



Seyedin 



9/27/86" 



Seyedin 



2/28/84 



Seyedin and Thomas 



12/9/861 



Seyedin and Thonaa 



1/7/86 



Nachan 



7 5 



10/31/8 



Urisc 



4 9 



6/19/84 



Urisc 



mm 



5 9 



C 11/6/9C 



Kuberasampach and Rueger 



7 6 



1 4 



II 8/2/88 



Urisc 



7 8 



91 7 



12/6/8C 



Urisc 



FOREIGN PATENT DOCUMENTS 



OATI- 



eouMTJi.r- 



CLAi* 



SUBCLASS 



T« AM JU A 



04 



2 5/9/ )0 Europe 



04 



1 11/7./ ifl ". Europe 



6/4/89 



Europe 



2 0 



7 4 



5/24/90 



Canada 



W6 <? / 



8 



OTHER OOCUMENT3 (l«cMit<» Author. Till: 0*f. Pertinent ffiej 



_Uri3C.ec al, Science . 220: 680-686 (1983) 



Luyten, ec'al, The Journal of Biological Cheaiacry, 264(23) : 13377-1336 



(Augusc 15, 1989) 
Sampach. ec al. Proc. Nacl. Acad. Sci. . 84: 7109-7113 (1987) 



Ozlc^y-.w. nc al.. The EM BO Journal . v. 9 no. 7: 2083-2093 (1990) 



EXAailMCff 



.71 



to CIS / o ' t |oate coNiiociieo 





XUSB/0& Substitute for form 1449A/PTO 



RMATION DISCLOSURE 
JEMENT BY APPLICANT 

(Use as many sheets as necessary) 



1 



of 



I 



18 



Complete if Known 



Application Number 



Filing Date 



First Named Inventor 



Art Unit 



Examiner Name 



Attorney Docket Number 



09/804,625 



March 9, 2001 



Wang 



1647 



D. Romeo 



08702.0039-02000 



U.S. PATENTS AND PUBLISHED U.S. PATENT APPLICATIONS 



Examiner 
Initials" 


Cite 
No. 1 


Document Number 


Issue or 
Publication 
Date 
MM-DD-YYYY 


Name of Patentee or 
Applicant of Cited 
uocumeni 


Pages, Columns, Lines, 

Where 
r\e ievan i Passages or 
Relevant 
Figures Appear 


Number-Kind 
Code 2 (if known) 






2,465,357 


29 Mar 1949 


Correll et al. 








3 ? 955 t 719 


11 May 1976 


Pheulpin 








4.191.747A 


04 Mar 1980 


Scheicher 








4,294,753 


13 Oct 1981 


Urist 








4,394,370 


19 July 1963 


Jeffries 








4,399,216 


16 Aug 1963 


Axel et al. 








4,419,446 


06 Dec *&8{b^ 


Howley et al. 








4,434,094 


28 Feb 1984 


Seyedin et al. 








4,441,915 


10 Apr 1984 


Arndt et al. 








4,455,256 


19Jun1984 


Urist . 








4,468,464 


28 Aug 1984 


Cohen et al. 










4.472,840 


25 Sept 1984 


Jefferies 










4.553,542 


19 Nov 1985 


Schenk et al. 










4,563,350 


07 Jan 1986 


Nathan et at. 










4,596,574 


24 June 1986 


Urist 










4,608,199 


26 Aug 1986 


Caplan et al. 










4,619,989 


28 Oct 1986 


Urist 










4,627,982 


09 Dec 1986 


Seyedin et al. 










4,642,120 


10 Feb 1987 


Nevo et al. - 










4,662,884 


05 May 1987 


Stenaas 










4,681,763 


21 Jul 1987 


Nathanson 








4,703,008 


27 Oct 1987 


Lin 








4,727,028 


23 Feb 1988 


Santerre et al. 








4,737,578 


12 Apr 1988 


Evans 








4,758,233 


19 Jul 1988 


Phillips et al. 








4,761,471 


2 Aug 1988 


Urist 








4,766,067 


23 Aug 1988 


Biswas et al. 








4,767,628 


30 Aug 1988 


Hutchinson 








4,769,328 


06 Sept 1988 


Murray et at. 








4,774,228 


27 Sept 1988 


Seyedin et al. 








4,774,322 


27 Sept 1988 


Seyedin et at. 








4,764,055 


15 Nov 1988 


Langen et al.