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Q Sterne Kessler 
Goldstein Fox 

ATTORNEYS AT LAW 




Robert Greene Steme 
Edward J. Kessler 
Jorge A. Goldstein 
David ICS. Comwell 
Robert W.Esmond 
Tracy-Gene G. Durldn 
Micnele A. Clmbala 
Michael B. Ray 
Robert E. Sokohl 
Eric n Steffe 
Michael Q. Lee 
Steven R. I^dung 
John M. Covert 
Linda E. Alcorn 
Robert C. Millonig 
Lav^ence B. Bugaisky 
CKmald J. Featherstone 
Michael V Messinger 



Judith U. Kim 
Timothy J. Shea, Jr 
Patrick E. Gan^ 
JefferyT. Helvey' 
Heidi LKraus 
Ciystal 0. Sayles 
Edward W.Yee 
Albert L. Ferto* 
Donald R. Banowit 
Peter A. Jadcman 
MollyA.McCall 
Teresa U. Medler 
Jeffrey S. Weaver 
Kendrick P. Patterson 
Vincent L Capuano 
Albert J. Fasulo 11* 
Eldora Ellison Floyd 
W. Russell Swindell 



Thomas C Fiala 
Brian J. Del Buono 
Virgil Lee Beaston* 
Reginald D. lucas* 
Kimberiy N. Reddick 
Theodore A. Wood 
Elizabeth J. Haanes 
Bruce E. Chalker 
Joseph S. Ostrtjff 
Frank R. Cottingham* 
Christine M. Lhuller 
Rae Lynn Prengaman*^ 
Jane shershenovich* 
Lawrence J. Carroll* 
George S. Bardmesser 
Rodney G. Maze 



September 6, 2002 



Rfgifleredf^temAgentt* 
Karen R. Martcowta 
Andrea J. Kamage 
NancyJ.Leith 
Ann t. Summerfield 
Helene C Carison 
Gaby L Lonasworth 
Matthew J. Dov^ 
Aaron L Schwartz 
Angelique G. Uy 
Bons A. Matvenko 
Maw B.Tung 
ICatnnaY.Pei 
Bryan L Skelton 
Robert A. Schwartzman 
Jason D. Eisenberg 
John J. FIgueroa 



Senior Counsel 
Samuel L Fox 
Kenneth C Bass 111 
Lisa A. Dunner 



*Admrtted onk in Maryland 

* Admitted on^ In Virginia 

* Admitted only in Texas 
•Practice Limited to 

Federal Agencies 



Writer 's Direct Number: 

(202)789-5525 

Internet Address: 

BRIAND@SKGF.COM 



Commissioner for Patents 
Washington, D.C. 20231 



Art Unit 1645 



Re: U.S. Utility Patent Application 

Appl. No. 09/848,616; Filed: May 4, 2001 
For: Molecular Antigen Array 
Inventors: Sebbel et aL 
Our Ref: 1 700.0 180002/JAG/BJD 



Sir: 



REC0VED 

SEP 1 0 2002 

TECHCENTER 160012900 



Transmitted herewith for appropriate action are the following documents: 

1. Executed Certificate Under 37 C.F.R. § 3.73(b) with attached copies of 
Assignments executed by all of the inventors; 

2. Executed Power of Attorney from Assignee; and 

3. One (1) return postcard. 



It is respectfully requested that the attached postcard be stamped with the date of filing of 
these documents, and that it be returned to our courier. In the event that extensions of time are 
necessary to prevent abandonment of this patent application, then such extensions of time are 
hereby petitioned. 



steme. Kessler, Goldstein & Fox p.LLC : 1100 New York Avenue, NW : Washington, DC 20005 : 202.371.2600 f 202.371.2540 : www.skgf.com 





Commissioner for Patents 
September 6, 2002 
Page 2 

The U.S. Patent and Trademark Office is hereby authorized to charge any fee deficiency, 
or credit any overpayment, to our Deposit Account No. 19-0036. 



Respectfully submitted, 



Sterne, Kessler, Goldstein & Fox p.l.l.c. 




Brian J. Del Buono 
Attorney for Applicants 
Registration No. 42,473 



BJD/nef 
Enclosures 



::ODMA\MHODMA\SKGF_DC 1 ;53343; 1 
SKGF Rev. 2/15/02 dew 



Steme; Kessler, Goldstein & Fox P.LLC : 1100 New York Avenue, NW : Washington, DC 20005 : 202.371.2600 f 202,371.2540 : www.skgf.com 




H RECEIVED 



SEP 1 0 2002 
TCCH CENTER 160012900 



Confirmation No. 60 IS 
Cytos Ref: PA016US 
SKGFRef: 1700.01S0002/JAG/BJD 



POWER OF ATTORNEY FROM ASSIGNEE 



Cvtos Biotechnology AG . a corporation of SWITZERLAND . having a principal place of business at 
WagistraBe 25. CH-8952 Ziinch-Schiieren. SWITZERLAND . is assignee of the entire right, title and interest for 
the United States of America (as defined in 35 U.S.C. § 100), by reason of an Assignment to the Assignee executed 

on / June j g ir d, 200 2 — ^ of an invention known as Molecular Antigen Arrav 

(Attorney Docket No. 1 700.0 180002/JAG/BJD), which is disclosed and claimed in a patent application of the same 
title by the inventor(s) Peter SEBBEL, Nicolas DUNANT. Manin BACHMANN. Alain TISSOT. Franziska 
LECHNER. Wolfgang A. RENNER. Frank HENNECKE. and Lars NIEB A (said application filed on Mav 4. 2001 
at the U.S. Patent and Trademark Office, having Application Number 09/843. 6 1 6) . 




0a3 



The Assignee hereby appoint the U.S. attorneys associated with CUSTOMER NUMBER 28393 to prosecute this 
application and any continuation, divisional, continuation-in-part, or reissue application thereof, and to transact all 
business in the U.S. Patent and Trademark Office connected therewith, such attorneys currendy being: Robert 
Greene Sterne, Esq., Reg. No, 28,912; Edward J. Kessler, Esq., Reg, No. 25,688; Jorge A. Goldstein, Esq., Reg. 
No. 29,021; David K.S. Comwell, Esq., Reg. No. 31,944; Robert W. Esmond, Esq., Reg. No. 32,893; Tracy-Gene 
G. Durkin, Esq., Reg. No. 32,831; Micheie A. Cimbala, Esq., Reg. No, 33,851; Michael B. Ray, Esq., Reg. No. 
33,997; Robert E. Sokohl, Esq., Reg. No. 36,013; Eric K. Steffe, Esq., Reg. No. 36,688, Michael Q. Lee, Esq,, Reg. 
No. 35,239; Steven R, Ludwig, Esq., Reg. No. 36,203; John M. Covert, Esq., Reg, No. 38,759; Linda E. Alcorn, 
Esq., Reg. No. 39,588; Lawrence B. Bugaisky, Esq., Reg. No. 35,086; Donald J. Featherstone, Esq., Reg. No. 
33,876; and Robert C. Millonig, Esq., Reg. No. 34,395. The Assignee hereby grants said attorneys the power to 
insen on this Power of Attorney any further identification that may be necessary or desirable in order toxomply with 
the rules of the U.S. Patent and Trademark Office, ^^-^^^^ ^ i 



Send correspondence to: 



STHRiVE, Kessler, Goldstein & Fox p.l.l.c. 
iiOO New York Avenue, N.W. 
Suite 600 

Washington, D.C, 20005-3934 
U.S.A. 



Direct phone calls to 202-371-2600. 



FOR: 



SIGNATURE: / 
i/ — 



BY: 
TITLE: 
DATE: 




I Q^QOtKgC&PSlS^K)^ Dr . Wolfg a ng Renner 



CEO 



June 3rd, 2002 



SKGF_DCI: 16231.1 



©2002 Sterne, Kessler, Goldstein & Fox p.l.l.c. 



::ODM A\M HODMA\SKCF_DCI : 1623 1 : 1 




Confirmation No. 601S 
Cytos Ref: PA016US 
SKGFRef: 1 700.0 180002/JAG/^JD 



Certificate Under 37 C.F.R. § 3.73(b) 



Applicant/Patent Owner: Peter SEBBEL. Nicolas DUNANT. Martin BACHMANN. Alain TISSOT, Franziska 

LECHNER. Wolfgang A. RENNER. Frank HENNECKE. and Lars NIEBA 



Application No./Patent No.: 09/848.616 

Entitled: • Molecular Antigen Array 



Filed/Issue Date: May 4. 2001 



Cvtos Biotechnology AG 



Corporation 



(Name ol* Assignee) (Type of Aisignee. e.g.. corporation, partnership, university, government agcncy.eic.) 

States that it is: 

1. [X] the assignee of the entire right, title, and interest, or 

2. [ ] an assignee of an undivided part interest 
in the patent application/patent identified above by virtue of either: 



RECEIVED 

SEP 1 0 2002 

TECH CENTER 1600/2900 



A. [X] An Assignment from the inventor(s) of the patent application/patent idendfied above. The assignment was 

recorded in the Patent and Trademark Office at Reel , Frame , or for which a copy thereof is 

attached. 

OR 

B. ( ] A chain of title from the inventor(s) of the patent application/patent identified above to the current 

assignee as shown below: 



1. From: 



To: 



2. From: 



The document was recorded in the Patent and Trademark Office at 

Reel , Frame , or for which a copy thereof is attached. 

To: 



3. From: 



The document was recorded in the Patent and Trademark Office at 

Reel , Frame , or for which a copy thereof is attached. 

To: 



The document was recorded in the Patent and Trademark Office at 

Reel , Frame , or for which a copy thereof is attached. 

[ ] Additional documents in the chain of title are listed on a supplemental sheet. 

[X] Copies of assignments or other documents in the chain of dtle are attached. 

fNOTE: A separate copy {i.e., the original assignment document or a true copy of the original 
document) must be submitted to Assignment Division in accordance with 37 CFR Part 3, if the 
assignment is to be recorded in the records of the PTO. See MPEP 302-302.8] 

The undersigned (whose tide is supplied below) is empowered to act on behalf of the assignee. 
Date: y " June 3iid, 2002 

Name: t^er^^i^iel^^ Wol/gang Renner 

Tide: 
Signature: 

SKCP_DCl:l62t6.l 




Confirmation No. 6018 
Cytos Ref: PA016US 
SKGFRef: 1 700.0 180002/JAG/BJD 

ASSIGNMENT 



In consideration of the sum of One Dollar ($1.00) or equivalent and other good and valuable 
consideration paid to each of the undersigned inventor(s): Peter SEBBEL. Nicolas DUNANT. Martin 
B ACHMANN. Alain TISSOT, Franziska LECHNER. Wolfgang A. RENNER, Frank HENNECKE. and 
Lars NIEBA , the undersigned inventor(s) hereby sell(s) and assign(s) to Cytos Biotechnology AG (the 
Assignee) his/her entire right, title and interest, including the right to sue for past infringement and to 
collect for all past, present and future damages: 

check applicable box(es) ® for the United States of America (as defined in 35 U.S.C. 

§ 100), 

ta and throughout the world, 

(a) in the inyention(s) known as Molecular Antigen Array for which application(s) for 
patent in the United States of America has (have) been executed by the undersigned on 
January 8, 2002: December 28, 2001 ; January 9, 2002: January 8, 2002: January 8. 2002: 
December 27, 2001: January 7, 2002: and January 5. 2002, respectively (also known as 
United States Application No. 09/848,616 , filed May 4, 2001) , in any and all 
applications thereon, in any and all Letters Patent(s) therefor, and 

(b) in any and all applications that claim the benefit of the patent application listed above 
in part (a), including continuing applications, reissues, extensions, renewals and 
reexaminations of the patent application or Letters Patent therefor listed above in part 
(a), to the full extent of the term or terms for which Letters Patents issue, and 

(c) in any and all inventions described in the patent application listed above in part (a), 
and in any and all forms of intellectual and industrial property protection derivable from 
such patent application, and that are derivable from any and all continuing applications, 
reissues, extensions, renewals and reexaminations of such patent application, including, 
without limitation, patents, applications, utility models, inventor's certificates, and 
designs together with the right to file applications therefor; and including the right to 
claim the same priority rights from any previously filed applications under the 
International Agreement for the Protection of Industrial Property, or any other 
international agreement, or the domestic laws of the country in which any such 
application is filed, as may be applicable; 

all such rights, title and interest to be held and enjoyed by the above-named Assignee, its successors, legal 
representatives and assigns to the same extent as all such rights, title and interest would have been held 
and enjoyed by the Assignor had tids assignment and sale not been made. 

The undersigned inventor(s) agree(s) to execute all papers necessary in connection with the 
application(s) and any continuing (continuation, divisional, or continuation-in-part), reissue, 
reexamination or corresponding application(s) thereof and also to execute separate assignments in 
connection with such application(s) as the Assignee may deem necessary or expedient. 

The undersigned inventor(s) agree(s) to execute all papers necessary in connection with any 
interference or patent enforcement action (judicial or otherwise) related to the application(s) or any 
continuing (continuation, divisional, or continuation-in-part), reissue or reexamination application(s) 



Page 1 of 2 



thereof and to cooperate with the Assignee in every way possible in obtaining evidence and going forward 
with such interference or patent enforcement action. 

The undersigned inventor(s) hereby represent(s) that he/she has full right to convey the entire 
interest herein assigned, and that he/she has not executed, and will not execute, any agreement in conflict 
therewith. 



The undersigned inventor(s) hereby grant(s) Robert Greene Sterne, Esquire, Registration No. 
28.912; Edward J. Kessler, Esquire, Registration No. 25,688; Jorge A. Goldstein, Esquire, Registration 
No. 29,021; David K.S. Com well, Esquire, Registration No. 31,944; Robert W. Esmond, Esquire, 
Registration No. 32,893; Tracy-Gene G. Durkin, Esquire, Registration No. 32,83 1 ; Michele A. Cimbala, 
Esquire, Registration No. 33,851; Michael B. Ray, Esquire, Registration No. 33,997; Robert E. Sokohl, 
Esquire, Registration No. 36,013; Eric K. Steffe, Esquire, Registration No. 36,688; Michael. Q. Lee, 
Esquire, Registration No. 35,239; Steven R. Ludwig, Esquire, Registration No. 36,203; John M. Covert, 
Esquire, Registration No. 38,759; Linda E. Alcorn, Esquire, Registration No. 39,588; Lawrence B. 
Bugaisky, Esquire, Registration No. 35,086; Donald J. Featherstone, Esquire, Registration No. 33,876; 
and Robert C. Millonig, Esquire. Registration No. 34,395, all of STERNE, KESSLER, Goldstein & Fox 
p.L.L.C, 1 100 New York Avenue, N. W., Suite 600, Washington, D.C. 20005-3934, power to insert in this 
assignment any further identification that may be necessary or desirable in order to comply with the rules 
of the United States Patent and Trademark Office for recordation of this document. 

IN WITNESS WHEREOF, executed by the undersigned inventor(s) on the date opposite his/her 

name. 

Datc^ /^^(^'t^j 30iiiO!^^^?W ^izniiturc of Inventor: / 

^ Peter SHBBEL 



Date:x/ Signature of Inventor: 



Nicolas DUNANT 



Date 



Date: 



: / ^ ^ Signature of Inventor: / "^^^^^^^ 

'^Martin BACHMANN 



^ 0/ O ^ Signature of Inventor: 



Alain TISSOT 



Date: / Si 



ignature of Inventor: / 

"^^^^anzii 



Date: 



Date: 




^ . ip, O Signature of Inventor: ^ ^^^^\[^ " ^ 



Frank HENNECKE 

Date: . / , Signature of Inventor: 



Lars NEEBA 



SKGF_DCI:I62I2.1 



.pro 



Page 2 of 2 



DO NOT FORWARD 
TO ASSIGNMENT BRANCH 
MOTPnR RPCORDATtQM 



SKGFRev. 12/31/01 mac 



EINGE6MGEH 0 3. Juni 2002 



Confirmation No. 6018 
Cytos Ref: PA016US 

rift wot ^O^^RlCH ^^^^ 1 700,0 180002/JAG/BJD 

.6%^^^^ ASSIGNMENT 



In consideration of the sum of One Dollar ($1.00) or equivalent and other good and valuable 
consideration paid to each of the undersigned inventor(s): Peter SEBBEL, Nicolas DUNANT, Martin 
B ACHMANN, Alain TISSOT. Franziska LECHNER. Wolfgang A. RENNER. Frank HENNECKE. and 
Lars NIEBA , the undersigned inventor(s) hereby sell(s) and assign(s) to Cytos Biotechnology AG (the 
Assignee) his/her entire right, title and interest, including the right to sue for past infringement and to 
collect for ail past, present and future damages: 

check applicable box(es) a for the United States of America (as defined in 35 U.S.C. 

§ 100), 

la and throughout the world, 

(a) in the invention(s) known as Molecular Antigen Array for which application(s) for 
patent in the United States of America has (have) been executed by the undersigned on 
January 8. 2002: December 28, 2001 : January 9. 2002: January 8, 2002: January 8, 2002: 
December 21. 2001; January 7, 2002: and January 5. 2002, respectively (also known as 
United States Application No. 09/848,616 , filed May 4. 2001) . in any and all 
applications thereon, in any and all Letters Patent(s) therefor, and 

(b) in any and all applications that claim the benefit of the patent application listed above 
in part (a), including continuing applications, reissues, extensions, renewals and 
reexaminations of the patent application or Letters Patent therefor listed above in part . 
(a), to the full extent of the term or terms for which Letters Patents issue, and 

(c) in any and all inventions described in the patent application listed above in part (a), 
and in any and all forms of intellectual and industrial property protection derivable from 
such patent application, and that are derivable from any and all continuing applications, 
reissues, extensions, renewals and reexaminations of such patent application, including, 
without limitation, patents, applications, utility models, inventor's certificates, and 
designs together with the right to file applications therefor; and including the right to 
claim the same priority rights from any previously filed applications under the 
International Agreement for the Protection of Industrial Property, or any other 
international agreement, or the domestic laws of the country in which any such 
applicadon is filed, as may be applicable; 

all such rights, title and interest to be held and enjoyed by the above-named Assignee, its successors, legal 
representatives and assigns to the same extent as all such rights, dtle and interest would have been held 
and enjoyed by the Assignor had this assignment and sale not been made. 

The undersigned inventor(s) agree(s) to execute all papers necessary in connection with the 
applicadon(s) and any continuing (continuation, divisional, or condnuation-in-part), reissue, 
reexamination or corresponding application(s) thereof and also to execute separate assignments in 
connecdon with such applicadon(s) as the Assignee may deem necessary or expedient. 

The undersigned inventor(s) agree(s) to execute all papers necessary in connecdon with any 
interference or patent enforcement acdon (judicial or otherwise) related to the application(s) or any 
continuing (condnuadon, divisional, or condnuadon-in-part), reissue or reexamination application(s) 



Page 1 of 2 



thereof and to cooperate with the Assignee in every way possible in obtaining evidence and going forward 
with such interference or patent enforcement action. 



The undersigned inventor(s) hereby represent(s) that he/she has full right to convey the entire 
interest herein assigned, and that he/she has not executed, and will not execute, any agreement in conflict 
therewith. 

The undersigned inventor(s) hereby grant(s) Robert Greene Sterne, Esquire, Registration No. 
28,912; Edward J. Kessler, Esquire, Registration No. 25,688; Jorge A. Goldstein, Esquire, Registration 
No. 29,021; David K.S. Com well, Esquire, Registration No. 31,944; Robert W. Esmond, Esquire, 
Registration No. 32,893 ; Tracy-Gene G. Durkin, Esquire, Registration No. 32,83 1 ; Michele A. Cimbala, 
Esquire, Registration No, 33,851; Michael B. Ray, Esquire, Registration No. 33,997; Robert E. Sokohl, 
Esquire, Registration No. 36,013; Eric K. Steffe,' Esquire, Registration No. 36,688; Michael Q. Lee, 
Esquire, Registration No. 35,239; Steven R. Ludwig, Esquire, Registration No. 36,203; John M. Covert, 
Esquire, Registration No. 38,759; Linda E. Alcorn, Esquire, Registration No. 39,588; Lawrence B. 
Bugaisky, Esquire, Registration No. 35,086; Donald J. Featherstone, Esquire, Registration No. 33,876; 
and Robert C. Millonig, Esquire, Registration No. 34,395, all of STERNE, KESSLER, GOLDSTEIN & Fox 
P.L.L.C., 1 100 New York Avenue, N.W., Suite 600, Washington, D.C. 20005-3934, power to insert in this 
assignment any further identification that may be necessary or desirable in order to comply with the rules 
of the United States Patent and Trademark Office for recordation of this document. 

IN WITNESS WHEREOF, executed by the undersigned inventor(s) on the date opposite his/her 

name. 



Date-^ I Signature of Inventor: 



Peter SEBBEL 



n^te:, /^/. ^ -?^^- ^l.nature of Inventor: / ^ ^ 1/^^^^^ ^ 

^ Nicolas DUNANT 



Date:. / Signature of Inventor: , 



Martin BACHMAIW 



Date: / Signature of Inventor: , 



'Alain TISSOT 



Date: / Signature of Inventor: / 

^ ^ranzis 



-ranziska LECHNER 

Date: / Signature of Inventor: 



Wolfgang A. RENNER 

Date: / Signature of Inventor: ^/ 

/ Frank HENNECKE 



Date: ( I Signature of Inventor: 



Lars NIEBA 

SKGF_DC1:16212.1 

TO Page 2 of 2 ^ cnflWATO SKGF Rev. 12A31/01 mac 



EINGEGANGEN 0 ^. Juni 200Z 

Confirmation No. 60 IS 

00 NOT ro''^.^,r*u Cytos Ref: PA016US 

''ilfff ^R^^^ SKCFRef: 1700.0 1 80002/JAG/BJD 

ASSIGNMENT 



In consideration of the sum of One Dollar (SI. 00) or equivalent and other good and valuable 
consideration paid to each of the undersigned inventor(s): Peter SEBBEL, Nicolas DUNANT. Martin 
RACHiMANN. Alain TISSOT. Franziska LECHNER. Wolfgang A. RENNER. Frank HENNECKE, and 
r.ars NIEBA . the undersigned inventor(s) hereby sell(s) and assign(s) to Cvtos Biotechnology AG (the 
Assignee) his/her entire right, title and interest, including the right to sue for past infringement and to 
collect for all past, present and future damages: 

check applicable box(es) a for the United States of America (as defined in 35 U.S.C. 

§ 100), 

3 and throughout the world, 

(a) in the invention(s) known as Molecular Antigen Array for which application(s) for 
patent in the United States of America has (have) been executed by the undersigned on 
January 8. 2002: December 28. 200 1 : January 9. 2002: January 8. 2002; January 8. 2002: 
December 27. 2001: January 7. 2002: and January 5. 2002. respectively (also known as 
United States Applicadon No. 09/848,616 . filed Mav 4. 2001) , in any and all 
applications thereon, in any and all Letters Patent(s) therefor, and 

(b) in any and all applications that claim the benefit of the patent application listed above 
in part (a), including continuing applications, reissues, extensions, renewals and 
reexaminadons of the patent applicadon or Letters Patent therefor listed above in part 
(a), to the full extent of the term or terms for which Letters Patents issue, and 

(c) in any and all inventions described in the patent apphcadon listed above in part (a), 
and in any and all forms of intellectual and industrial propeny protection derivable from 
such patent applicadon, and that are derivable from any and all condnuing applications, 
reissues, extensions, renewals and reexaminadons of such patent application, including, 
without limitation, patents, applications, utility models, inventor's certificates, and 
designs together with the right to file applications therefor; and including the right to 
claim the same priority rights from any previously filed applications under the 
International Agreement for the Protection of Industrial Property, or any other 
international agreement, or the domestic laws of the country in which any such 
application is filed, as may be applicable; 

all such rights, title and interest to be held and enjoyed by the above-named Assignee, its successors, legal 
representatives and assigns to the same extent as all such rights, tide and interest would have been held 
and enjoyed by the Assignor had this assignment and sale not been made. 

The undersigned inyentor(s) agree(s) to execute all papers necessary in connection with die 
application(s) and any continuing (continuation, divisional, or continuation-in-part), reissue, 
reexamination or corresponding application(s) thereof and also to execute separate assignments in 
connection with such application(s) as the Assignee may deem necessary or expedient. 

The undersigned inventor(s) agree(s) to execute all papers necessary in connection with any 
interference or patent enforcement action (judicial or otherwise) related to the application(s) or any 
continuing (continuation, divisional, or continuation-in-part), reissue or reexamination application(s) 



Page I of 2 



thereof and to cooperate with the Assignee in every way possible in obtaining evidence and going forward 
with such interference or patent enforcement action. 

The undersigned inventor(s) hereby represent(s) that he/she has full tight to convey the entire 
interest herein assigned, and that he/she has not executed, and will not execute, any agreement in conflict 
therewith. 

The undersigned inventor(s) hereby grant(s) Robert Greene Sterne, Esquire, Registration No. 
28,912; Edward J. Kessler, Esquire, Registration No. 25,688; Jorge A. Goldstein, Esquire, Registxauon 
No. 29,021; David K.S. Com well, Esquire, Registration No. 31,944; Robert W. Esnnond, Esquire, 
Registration No. 32,393; Tracy-Gene G. Durkin, Esquire, Registration No. 32,831; Michele A. Cimbala. 
Esquire, Registration No. 33,851; Michael B. Ray, Esquire, Registration No. 33,997; Robert E. Sokohl, 
Esquire, Registration No. 36,013; Eric K. Steffe, Esquire, Registration No. 36,688; Michael Q, Lee. 
Esquire, Registration No, 35,239; Steven R. Ludwig, Esquire, Registration No. 36,203; John M. Covert, 
Esquire, Registration No. 38,759; Linda E. Alcorn, Esquire, Registration No. 39,588; Lawrence B. 
Bugaisky, Esquire, Registration No. 35.086; Donald J. Featherstone, Esquire, Registration No. 33,876; 
and Roben C. Millonig, Esquire, Registration No. 34,395, all of STERNE, KESSLER, GOLDSTEIN & Fox 
P.L.L.C., 1 100 New York Avenue, N.W., Suite 600, Washington, D.C. 20005-3934, power to insert in this 
assignment.any further identification that may be necessary or desirable in order to comply with the rules 
of the United States Patent and Trademark Office for recordation of this document. 

IN WITNESS WHEREOF, executed by the undersigned inventor(s) on the date opposite his/her 

name. 

Date; / Signature of Inventor: / 



V' Peter SEBBEL 



Date:, 



Signature of Inventor: / 



^ Nicolas DUNANT 



Date:. / Signature of Inventor: 



Martin BACHMANN 



Date: / ^ Signature of Inventor: . 



'Alain TISSOT 



Date: / ^ ^- ^ Signature of Inventor: / Im^cJ^ 

" *^Franziska LECHNER 



Date: / Signature of Inventor: 



Wolfgang A. RENNER 



Date: / Signature of Inventor: ,/ 

Frank HE^f^fECKE 



-4- 



Date: , 1 - Signature of Inventor: 



^ Lars NIEBA 

SKCF.DCI: 16212.1 

0I5.PTO Page 2 of 2 SKGF Rev. I2ni/0l mac 

DO NOT FORWARD 



Confirmation No. 601S 
Cytos Ref: PA016US 
SKGFRef: 1700.0 180002/JAG/BJD 

ASSIGNMENT 



In consideration of the sum of One Dollar (SI. 00) or equivalent and other good and valuable 
consideration paid to each of the undersigned inventor(s); PecerSEBBEL. Nicolas DUNANT. Maain 
R ACHMANN. Alain TISSOT. Franziska LECHNER. Wolfgang A. RENNER. Frank HENNECKE. and 
r.ars NIEBA . the undersigned inventor(s) hereby selKs) and assign(s) to Cvcos Biotechnology AG (the 
Assignee) his/her entire right, title and interest, including the right to sue for past infringement and to 
collect for all past, present and future damages: 

check applicable box(es) a for the United States of America (as defined in 35 U.S.C. 

§ 100), 

s and throughout the world, 

(a) in the invention(s) kjiown as Molecular Antigen Array for which application(s) for 
patent in the United States of America has (have) been executed by the undersigned on 
January 8, 2002: December 28. 2001: January 9. 2002: January 8, 2002: January 8. 2002: 
December 27. 2001: January 7. 2002: and January 5. 2002. respectively (also known as 
United States Application No. 09/848.616 . filed Mav 4. 2001) , in any and all 
applications thereon, in any and all Letters Patent(s) therefor, and 

(b) in any and all applications that claim the benefit of the patent application listed above 
in part (a), including continuing applications, reissues, extensions, renewals and 
reexaminations of the patent application or Letters Patent dierefor listed above in part 
(a), to the full extent of the term or terms for which Letters Pacents issue, and 

(c) in any and all inventions described in the patent application listed above in part (a), 
and in any and all forms of intellectual and industrial propeny protection derivable from 
such patent applicadon, and that are derivable from any and all continuing applications, 
reissues, extensions, renewals and reexaminadons of such patent applicadon, including, 
without limitation, patents, applicadons, utility models, inventor's certificates, and 
designs together with the right to file applications therefor; and including the right to 
claim the same priority rights from any previously filed applications under the 
International Agreement for the Protecdon of Industrial Property, or any other 
international agreement, or the domestic laws of the country in which any such 
applicadon is filed, as may be applicable; 

all such rights, title and interest to be held and enjoyed by the above-named Assignee, its successors, legal 
representadves and assigns to the same extent as all such rights, dtle and interest would have been held 
and enjoyed by the Assignor had this assignment and sale not been made. 

The undersigned inventor(s). agree(s) to execute all papers necessary in connection with the 
applicadon(s) and any continuing (continuation, divisional, or condnuadon-in-part), reissue, 
reexaminadon or corresponding applicadon(s) thereof and also to execute separate assignments in 
connection with such application(s) as the Assignee may deem necessary or expedient. 

The undersigned inventor(s) agree(s) to execute all papers necessary in connection with any 
interference or patent enforcement action (judicial or otherwise) related to the application(s) or any 
continuing (continuation, divisional, or continuation-in-part), reissue or reexamination application(s) 



00 MOTFORWABD^., 
TO ASSIGNMENT BRANCH 
jiQLEBBiKQBQfillQIl 



Page 1 of 2 



thereof and to cooperate with the Assignee tnevery way possible inobtaining evidence and going forward 
with such interference or patent enforcement action. 

The undersigned inventor(s) hereby represenc(s) that he/she has full right to convey the entire 
interest herein assigned, and that he/she has not executed, and will not execute, any agreement in conflict 
therewith. 

The undersigned inventor(s) hereby grant(s) Robert Greene Sterne, Esquire, Registration No. 
28,912; Edward J. Kessler, Esquire, Registration No. 25,688; Jorge A. Goldstein, Esquire, Registration 
No. 29,021; David K.S. Comwell, Esquire, Registration No. 31.944; Robert W. Esmond, Esquire, 
Registration No. 32,893; Tracy-Gene G. Durkin, Esquire, Registration No. 32,831; Michele A. Cimbala. 
Esquire, Registration No. 33,851; Michael B. Ray, Esquire, Registration No. 33,997; Robert E. Sokohl, 
Esquire, Registration No. 36,013; Eric K. Steffe, Esquire, Registration No. 36,688; Michael Q. Lee, 
Esquire, Registration No. 35,239; Steven R. Ludwig, Esquire, Registration No. 36,203; John M. Covert, 
Esquire, Registration No. 38,759; Linda E. Alcorn, Esquire, Registranon No. 39,588; Lawrence B. 
Bugaisky, Esquire, Registration No. 35,086; Donald J. Featherstone, Esquire, Registration No. 33,876; 
and Robert C. Millonig, Esquire, Registration No. 34,395, all of STERNE, KESSLER, GOLDSTEIN & Fox 
P.L.L.C., 1 100 New York Avenue, N. W., Suite 600, Washington, D.C. 20005-3934, power to insert in this 
assignment.any further identification that may be necessary or desirable in order to comply with the rules 
of the United States Patent and Trademark Office for recordation of this document. 

IN WITNESS WHEREOF, executed by the undersigned inventor(s) on the date opposite his/her 

name. 

Date; / Signature of Inventor: / 



^ Peter SEBBEL 



Date: . / Signature of Inventor: 



: / 



^ iMicoias DUN.AiNT 

Date:. / Signature of Inventor: f „_ 



Martin B ACHMANN 



Date: / ^ Signature of Inventor: 



'Alain TISSOT 



Date: ^ Signature of Inventor: / 



"J '^Franziska LECHNER 

Date: / Signature of Inventor: , 



Wolfgang A. RENNER 
Date: Signature of Inventor ^/ 

Date: , / ^ ' ^ ^^^0 ^ Signature of Inventor: 




SKCF.DCl: 16212.1 



015.PTO 



Page 2 of 2 



DO NOT FORWARD 
TO ASSIGNMENT BRANCH 
Mm POP RPrnnnATiON 



SKGFRcv. I2ni/01 mnc