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International Journal of Trend in Scientific Research and Development (IJTSRD) 

Volume 4 Issue 4, June 2020 Available Online: www.ijtsrd.com e-ISSN: 2456 - 6470 

CoVID-19, A Man Made Disaster & Its Treatment 

Dr. Sinchan Das, Priyankesh Mishra, Swastika Subba 

Humanity Institute of Advanced Medical & Cultural Research 


ABSTRACT 


Time and again history has been a proof that every time humans tried to 
interfere with the nature, it has always returned their reward in more 
destructive and irreversible way. The epidemic and pandemic like Plague of 
Athens, Influenza, Antonine plague. Cholera pandemic. Flu pandemic & its 
consequent infections and recently followed by most virulent of all, Covid-19. 
Likewise, COVlD-19 is a reward back to those who expected its creation for the 
fulfillment of their greed. The contradictions still lies as countries are busy 
proving it to be natural and not the cultivations of highly developed so called 
self-proclaimed lords around the world. But the irony here is, they are the one 
who are highly been affected by this deadly pathogen called SARS-CoV-2. The 
main getaway for this particular virus is through Angiotensin- converting 
Enzyme- 2 (ACE-2] &TMPRSS2 causing further infection within the body. The 
main role player, responsible for this deadly infection is the oxidative stress, 
which can be the decision maker for majority of the diseases. All these are the 
outcomes of the faulty habits of the human beings and the major contribution 
goes to saviours of human kind, the so called pharmaceuticals lords who have 
made each and everyone more and more drug dependent. Despite of the 
evidences of their faults and fallacies, the world is relying on them to come out 
with the solution rather than giving equal chance to the other fields of 
medicine, like Homeopathy, Yoga, Ayurveda, Siddha, Unanl, Biochemic mode of 
treatment e.t.c.. It should be keep in mind that, treatments are not sufficient to 
eradicate these pathological conditions, nor the artificial preventive measures 
like the vaccines. To eradicate these pathologies we have to stop manipulating 
the nature and we have to careful about the hygiene, both external and 
Internal. Well, if world cannot take these fields under consideration and 
believe it to be the medicines based on theories or trailers than its time they 
roll back to history and see what they have contributed to the society. One 
very good example can be seen in case of 1918’s Elu pandemic where people 
were in crisis and their no hope for their survival, at that particular time if 
Homeopathic medicine Gelsemium had not come for rescue than outcomes 
would have been worst. Such many examples and their record of contribution 
can be seen through the course of history yet the Governments around the 
world do not consider them as a field of Medical science, they exist just for a 
name sake. If you think that creating vaccines, antidotes, antiviral and 
antibiotics is the Medical Science then the deaths rate that we see today due to 
various reason is the resultant of this science. 

KEYWORDS: CoVID-19, CoVlD-19 and Homoeopathy, Homoeopathic treatment of 
CoVID-19, Infections, Natural disasters 



How to cite this paper: Dr. Sinchan Das | 
Priyankesh Mishra | Swastika Subba 
"CoVlD-19, A Man Made Disaster & Its 
Treatment" 

Published in 

International Journal 
of Trend in Scientific 
Research and 

Development 
(ijtsrd], ISSN: 2456- 
6470, Volume-4 | 
lssue-4, June 2020, pp.277-295, URL: 
www.ijtsrd.com/papers/ijtsrd30963.pdf 

Copyright © 2020 by author[s] and 
International Journal of Trend in Scientific 
Research and Development Journal. This 
is an Open Access article distributed 
under the terms of r-"y ' 

the Creative 

Commons Attribution 
License [CC BY 4.0] 

[http://creativecommons.org/licenses/by 
/4.0] 


INTRODUCTION 

Earth, a divine creation of universe; a planet having all 
sources of life and life preserving resources. A beautiful 
planet that is well-designed to maintain its Integrity and 
existence. Among many other components of this nature, 
human beings are one component. Human beings, the self- 
declared lord or self-declared most intelligent species of this 
nature. Nature is a balanced state, where each and every 
components of her can live harmoniously, under a clearly 
defined principle. Eor nature, every component is of equal 
Importance and they are inter-dependable to each other; any 
harm to any of them can lead to a serious gross 
disequilibrium and followed by an irreversible damage. 
Irrespective of our acceptability or ignorance. Human beings 
are the most complex species, who are able to think, 
preserve and destroy; actually, being the delayed product of 


evolution, they are empowered to protect themselves from 
the usual natural insults and also to protect all other natural 
components in order to maintain natural equilibrium. To 
maintain this natural equilibrium, it is necessary to 
understand the natural principle and circumstances in an 
unbiased and thorough manner; that is why education is 
designed. This psychology of enquiry, is not developed by 
the mankind at all, it is the gift of nature. Every species have 
their own forms of enquiry and Intelligence, human beings 
are not an exceptional one. Among the prides of mankind, 
development of‘Science’ is the principal one. 

Science is a subject which is designed to understand and 
explain the natural phenomena, with the help of a universal 
language, understandable to everyone. But now days, science 


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has become an instrument of humanitarian complexes; 
where it is now used to design instruments which are able to 
damage the entire nature. The blessings now become the 
curse, the responsible factor of natural destruction. A subject 
which is designed to explain natural phenomena with the 
light of logic, now become the subject which can deny 
natural facts and events in a wondering manner. The style of 
human race is to ignore the actual facts where they must be 
guilty and blaming others to hide their own guilt. Human 
race is the responsible factor for all the environmental 
pollution and destructions. 

In this century, the world has faced a deadly monster, 
named CoVld-19. More than hundred years, since the 
outbreak of the Influenza pandemic of 1918, the world now 
seems to face this pandemic in larger extent. The outbreak of 
SARS-CoV-2 infection is spreading to every continent, 
affecting a large number of populations worldwide; forcing 
the mankind to close themselves within their houses and has 
compelled us to live with this deadly pathogen for perhaps a 
long time. Further, this particular pandemic is compelling 
the scientists and clinicians to re-analyze the faults and 
fallacies of the medical system in respect to these collapsing 
medical fraternities. 

The histories of the pandemic and the Introduction of new 
viruses are not new rather it’s as old as the theatres of the 
earth’s civilization. After each epidemic & pandemic or any 
outbreaks a new virus emerges that have something in 
common from the virus that previously existed. So, can we 
say that viruses we discuss today are actually the new? Or 
the evolved or point/frame shift mutated virus? According to 
genetics, mutations are the root cause of the evolution; 
evolutions occur due to the changes in the environment. So, 
environment is the factor that is getting harmed by everyone 
day-by-day that led to new evolution or the environment in 
which these particular viruses reside. So, for the 
development of a disease, environment must play an 
important role. From the definition of health, given by World 
Health Organization [WHO], one can find three parameters 
in order to qualify health as a whole, which are— 
Psychological, Physical & Social parameters; but in reality 
there is another missing but most important parameter, i.e. 
Environmental factor. Environment or nature where all the 
natural components [microorganisms, plants, animals, 
humans] live in a harmonious manner in order to maintain 
proper harmony. Eor the maintenance of this natural 
harmony, equilibrium should be maintained between all the 
components of the nature. But, our humanitarian complex is 
drastically damaging this social equilibrium in a dangerous 
way. We all are running behind a virtual health by 
compromising the actual one. 

Although after a long while, we have witnessed such a 
pandemic, which have become the cause of fear around the 
globe. But one can easily find that, we are residing in a 
diseased and drug-dependent era, where the entire world is 
submerged under the dump of several diseases. However, 
with the advancement in Medical technology, we have 
avoided many infectious diseases, but in exchange of several 
autoimmune and metabolic diseases. Regardless, CoVid-19 is 
a major health concern, as it is a rapidly growing infectious 
disease with serious as well as devastating outcomes, 
especially the ones who are susceptible to this disease. In 


this modern era, when we feel too much satisfied with our 
complexes and hyper-scientific fast lifestyle, a viral disease 
has collapsed all the systems in a drastic manner. Those 
continents which are declared as developed have become 
more affected by this deadly virus. There are numerous 
questions that gets arise during this pandemic— 

> What is the cause of this Infection susceptibility? 

> Why this outbreak? 

> What is the cause behind these death incidences? 

> Why this left uncontrollable? 

Eunction of ACE is to convert Angiotensin into Anglotensln-1, 
in order to raise the blood pressure to meet the metabolic 
need of the body. But the prolonged elevation is commonly 
diagnosed as the Hypertension. When ACE inhibitors or 
Angiotensin receptor blockers are administers in order to 
control the blood pressure, without giving a minimum 
emphasis on the cause responsible for the particular 
elevation & the body becomes a victim of drug- dependent 
pathology. In that time, our body starts to synthesize another 
homologous enzyme having the potential to exhibit anti- 
hypertensive properties. But, the actual cause behind the 
elevation still remains unchecked and additionally, body has 
become more damaged by the artificial chemical substance. 
As a result of this, after a considerable time, a series of 
additional manifestations starts to appear and serious multi¬ 
organ involvement is then encountered. By this means an 
individual has become a victim of drug-dependent pathology. 
In these conditions, the nature will identify that individual as 
a diseased individual. Hippocrates said, ‘Nature is the best 
physician’; apart from being a best physician nature also has 
the potential to control all the natural diseases, with her own 
efficiency. Interrupting with this particular process, is 
nothing but contributing in complicating the mechanism 
more & more. 

Erom the very beginning, we have been residing in that 
environment where viruses & bacteria are all living in a 
harmonious manner. They are not at all interested in 
infecting anybody, until & unless they get a suitable 
environment to reside. When your body becomes impure 
Internally and running against the natural rule, nature will 
consider you as a diseased material and in that respect 
microorganisms are the natural scavengers. Infection of the 
virus must be associated with accumulation of impurities 
within the body, where they are present to clean up those 
impurities. In case of CoVlD-19, the affinity of the SARS-CoV- 
2 is those individuals who possess a prior diseased 
environment, as they have over expression of ACE2 & 
TMPRSS2. So, the targets are already diseased, that is why 
the site of infection for SARS-CoV-2 is those tissues which 
have higher expression of those materials. Therefore, SARS- 
CoV-2 is not a cause by any means; it is just a natural 
scavenger. 

Although there are several evidences regarding the 
inappropriateness and adverse effects of the vaccines, but 
the scientific community is surprisingly endorse these 
vaccines in a strange manner. Adverse effects of vaccines are 
much more higher than the beneficial effects of vaccine. In 
order to control Infection, by targeting a microorganism and 
by ignoring the root cause of infections, they have damaged 
the organism in a serious manner, generation after 
generation. 


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Rate 


International Journal of Trend in Scientific Research and Development [IJTSRD] @ www.iitsrd.com elSSN: 2456-6470 


90 iTTAi, vrA-iwnos math 

14.—DaaWi ftalM tar All r«nM: Pwtii 

rvcialrarlian SUrtaa. ■•OO-aa. United »>■!—. I9SS-40 


AM par MAMO 



Figure 1 BCG (TB vaccine) was introduced in 1953, after TB had already declined 

82 VITAL BTATiaTICB RATIS 

Figurr 16.—Orath Rates for Typhoid Fever: Death-refistralion States, 

1900-32, and United States, 1933-60 



isoo ifio itao isjo iMO isao leao 
Figure 2 No widespread vaccination program for Typhoid hut the disease still declined 



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Origin of the Pandemics: 

CoVlD-19 is the largest pandemic of the human civilization, which travels considerably a long distance, and most efficiently 
affects a larger number of populations with a notable virulence. The rate of global involvement in CoVlD-19 is surprising & 
horrible because it is relatively impossible to maintain this kind of virulence across the globe, in different temperature and 
geographical conditions. 

There are Innumerable evidences stated the direct relationship between urbanization, war & ever growing rates of Infections. 
Under the mask of sanitization, vaccination & e.t.c. the human race is promoting and designing infection favorable polluted 
conditions desperately. The incidences of epidemic, pandemics and Infections are always have a direct connection with the 
environmental pollutants, which are the gifts from the human civilization. Day by day we have done several manipulations with 
our environment to satisfy our superiority complexes. 


Sr. No. 

Pandemic/ Epidemic 

Association 

Year 

01 

Plague of Athens 

Pelloponesian war 

430B.C.-426B.C. 

02 

Influenza 

Roman war 

412 B.C. 

03 

Antonlne plague 

Italian war 

165 A.D. to 180 A.D. 

04 

Plague of Justinian 

War result 

541A.D.-542A.D. 

05 

Cholera pandemic 

British Invasion 

1817,1823,1826 

06 

Flu pandemic & its consequent infections 

World war-1 

1918 

07 

CoVlD-19 

Series of war, pollutions, environmental 
destruction, chemical hazards, drugs & e.t.c. 

2019 


From the above discussion, it is easily to encounter the direct relationship between the war, urbanization & Infections. It is the 
result of our all the misdeeds and disasters made by us. From the ancient time, microorganisms act as the natural scavenger, 
who are meant to digest the environmental pollutants. 

CoVID-19: 

CoVlD-19 or Corona Virus Disease-2019 is a mild to severe infectious & highly communicable disease, mainly affecting the 
respiratory system, but also spread to other several organs, like heart, kidney, liver e.t.c.. It is caused by a virus, named ‘SARS- 
CoV-2’ [Severe Acute Respiratory Syndrome Corona virus 2), which is transmitted chiefly by contact with infectious material 
[such as Respiratory droplets], characterized by fever, sore throat, oppression of chest, shortness of breath and may progress 
to pneumonia, fibrosis of the lung & respiratory failure. 

This monstrous viral disease of 2019 has expanded from Wuhan throughout the China and is being exported to a growing 
number of countries, some of which have seen onward transmission. Notably, most cases of CoVlD-19 is found in those areas of 
the world, which are considerably developed, higher in pollution, rich in industries and whose annual medical expenditure is 
comparatively higher than the others. 

Cause Behind Viral Modification: 

The materialistic scientific community is too much worried about the genomic organization of the SARS-CoV-2, because this 
virus is continuously changing its genomic organization which means its evolving very rapidly. But this is not at all a serious 
mystery. Microorganisms are one of the natural components, like humans. Their purpose is to digest and clean the impurities 
from the nature as well as from the diseased components of the nature. But, we human beings are continuously damaging the 
nature consciously & desperately. We are responsible for the natural disequilibrium of the modern time. We have destroyed the 
natural harmony for our cheap benefit, as a result of which a huge amount of pollutants are accumulated within us and our 
surroundings. Our limited hyper materialistic biased mentality is the culprit for all these kind of one-sided harmful behaviour, 
we have made. We are behaving in a blphasic manner, where we are creating enormous amount of impurities, as a result of that 
we are becoming diseased; on the other hand, we are trying to kill microorganisms, which are Important for the maintenance of 
the natural equilibrium. 

Viruses are as similar as other members of this natural family. In this ever changing natural environment, they also have to 
evolve themselves, to save their life and also adaptation from their side is important for their scheduled function, i.e. cleaning of 
the impurities. It is neither a strange phenomenon nor very supersizing. If they have to survive, they also have to evolve to a 
complexes form, like the humans. The evolution of the humans is suggesting that evolutions of the today’s human beings are 
also for the purpose for survival. So, if humans can evolved in a more complex form than their previous form for the survival 
then why not microorganisms. Deigning of the vaccines and ever-growing administration of them can satisfy our hyper 
conscious humanitarian complex mentality, but it ultimately can create confusion in the body’s field. Another dangerous fault of 
this system is that; we are considering ourselves as god and we love to; but actually we are nothing but a minutest dust particle 
in respect to this creation. 

The evolutions of the viruses are just qualifying Darwin’s two theories, i.e. 

1. Struggle for existence 

2. Survival for the fittest. 


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So, the viral or microorganism community is just struggling for the purpose of survival. This explanation is applicable only if the 
virus is naturally originated. But, there are several evidences about the artificiality of the particular virus. This virus is 
considered as artificial because- 

> Rate of modification is abnormally high 

> It is not affected by geographical difference 

> It is not affected by temperature 

> It adapts very rapidly the geographical modification 

> It acts through such a gateway, which is chiefly and knowingly man made 

It is very obvious that, materialistic scientific community will surely deny this facts and they must be indulge themselves to 
prove its natural origin. They will also arrogantly argued to promote the poisonous rumor of vaccines and anti-virals in order to 
satisfy the pharmaceutical lords. 

Risk Groups: Although peoples of diverse age group, sex, geographical distribution and occupation are readily affected by 
SARS-CoV-2, but among those who are in the red zone- 


Total CoVlD-f Cases according to age 

100 



S0+ 70-79 60-69 50-59 40-49 30-39 20-29 101 0-9 


Source: CCDC&P, CDC, CNN, BBC, Field survey Figure 04 


Rank 

Age 

Sex 

Co-Morbidities 

Gateways 

Cause 

01 

80-1- 

> Male-82% 

> Female-71% 

> Cardlo-vascular diseases 

> Metabolic diseases 

> Bronchial asthma 

> Post tubercular lung 

> Addiction 

> Prostate pathology [Male] 

> Carcinogenic pathologies 

> Renal pathology 

> Autoimmune Disorders 

> Immuno-compromization 

> History of HRT 

> Psychological Disturbances 

> Neuro-Degenerative diseases 

> Endometrial pathology [Female] 

> Drug-abuse 

> Nutritional deficiency 

> ACE2 

> TMPRSS2 

Oxidative 

Stress 

02 

70-79 

> Male-79% 

> Female-57% 

> Cardlo-vascular diseases, 

> Metabolic diseases, 

> Bronchial asthma, 

> Addiction, 

> Prostate pathology [Male] 

> Carcinogenic pathologies 

> Renal pathology 

> HRT 

> Psychological Disturbances 

> ACE2 

> TMPRSS2 

Oxidative 

Stress 


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> Neuro-degenerative Diseases 

> Autoimmune Disorders 

> Immuno- compromization 

> Endometrial pathology [Female] 

> Drug-abuse 

> Nutritional deficiency 



03 

60-69 

> Male-72% 

> Female-52% 

> Cardio-vascular diseases, 

> Post tubercular lung 

> Metabolic diseases, 

> Bronchial asthma, 

> Addiction, 

> Prostate pathology [Male] 

> Carcinogenic pathologies 

> Renal pathology 

> Autoimmune Disorders 

> Immuno-compromization 

> Psychological disturbances 

> Neuro-degenerative diseases 

> Stress 

> Endometrial pathology [Eemale] 

> Drug-abuse 

> Nutritional deficiency 

> ACE2 

> TMPRSS2 

Oxidative 

Stress 

04 

50-59 

> Male-70% 

> Female- 48% 

> Cardio-vascular diseases, 

> Metabolic diseases, 

> Bronchial asthma 

> Post-tubercular lung 

> Addiction, 

> Prostate pathology [Male] 

> Carcinogenic pathologies 

> Renal pathology 

> Autoimmune Disorders 

> Immuno-compromization 

> Psychological disturbances 

> Stress 

> Sexual disturbances 

> Endometrial pathology [Eemale] 

> Drug-abuse 

> Nutritional deficiency 

> ACE2 

> TMPRSS2 

Oxidative 

Stress 

05 

40-49 

> Male-68% 

> Female- 46% 

> Cardio-vascular diseases 

> Metabolic diseases 

> Bronchial asthma 

> Addiction 

> Post tubercular lung 

> Prostate pathology [Male] 

> Carcinogenic pathologies 

> Renal pathology 

> Autoimmune Disorders 

> Immuno-compromization 

> Psychological disturbances 

> Stress 

> Sexual disturbances 

> Endometrial pathology [Eemale] 

> Drug-abuse 

> Nutritional deficiency 

> ACE2 

> TMPRSS2 

Oxidative 

Stress 

06 

30-39 

> Male-32% 

> Female-15% 

> Cardio-vascular diseases, 

> Metabolic diseases, 

> Bronchial asthma, 

> Addiction, 

> Prostate pathology [Male] [Rare] 

> Carcinogenic pathologies 

> Renal pathology [Rare] 

> Autoimmune Disorders 

> Immuno-compromization 

> Psychological disturbances 

> Stress 

> ACE2 

> TMPRSS2 

Oxidative 

Stress 


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> Sexual disturbances 

> Endometrial pathology [Female] 

> Drug-abuse 

> Nutritional deficiency 



07 

20-29 

> Male-09% 

> Cardio-vascular diseases [Rare] 

> Metabolic diseases [Rare] 

> Bronchial asthma 

> Post tubercular lung 

> Addiction, 

> Prostate pathology [Male] [Rare] 

> Carcinogenic pathologies 

> Renal pathology [Rare] 

> ACE2 

Oxidative 

> Female-02% 

> Autoimmune Disorders 

> Immuno-compromization 

> Psychological disturbances 

> Stress 

> Sexual disturbances 

> Endometrial pathology [Female] [Rare] 

> Drug-abuse 

> Nutritional deficiency 

Stress 


C0VID+ cases according to Sex 


9 
8 
7 
6 
5 
4 
3 
2 
1 

Source: CCDC&P, CDC, CNN, BBC, Field survey Figure 05 

From the above discussion, one can easily figure out that the cause of this viral outbreak is entirely dependent upon two 
gateways, which are Angiotensin- converting Enzyme- 2 {ACE-2) & TMPRSS2, which can act as a gateway of this infection. 
The production of ACE2 is largely dependent upon the administration of ACE inhibitors & Angiotensin Receptor Blockers 
[ARB], which are used to treat metabolic disorders and some other pathological conditions worldwide. The over expression of 
TMPRSS2 is common in elderly male people, as this is associated with deregulation of androgen cycle, which results into 
different prostate pathologies, sexual pathologies and in women this is associated with different endometrial pathologies. So, 
the entry points are already prepared to welcome the virus by our hyper-concerned systems and careless attitudes. One can 
easily make out from the above discussion; SARS-CoV-2 is just a result, not the cause of this global collapse. Before shifting to 
clinical features, one should take a view on oxidative stress, discussed under the heading of Aetiopathology. 

AETIOPATHOLOGY: 

The aetiological factor, which can provide a suitable environment for the virus and also which can make an individual prone to 
be affected by this virus is the ‘Oxidative damage’ or ‘Oxidative stress’, where overproduction and increased level of oxygen free 
radicals can be encountered. Reactive oxygen species [ROS], such as superoxide anions & hydroxyl radical are unstable 
molecules that can initiate oxidation via unpaired electrons. The superoxide anion can either react with NO, to form a highly 
reactive peroxynitrite molecule or be rapidly converted to hydrogen peroxide by superoxide dismutase. H 2 O 2 can be converted 
into the damaging OH in the presence of Fe2+; this process is called the Fenton reaction, OH can also be generated from 0 "2 via 
the Haber-Weiss reaction. In the presence of chloride [Ck] and bromide (Br") ions, H 2 O 2 is catalyzed by heme peroxidases or 
myeloperoxidase to form hypochlorous acid [HOCl] and hypobromous acid [HOBr], which are very damaging oxidants. High 
levels of ROS have been implicated in the oxidation of proteins, lipids and DNA; this oxidation can result in tissue injury and 
inflammatory responses. The protein oxidation leads to dissregulation in the Ubiquitin- Proteasome pathway, which exhibits a 



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diphasic reaction along with suppressing the physiological apoptosis. The biphasic reaction will be inhibition of 26S & 20S 
proteasome; which results into formation of highly reactive aldehydes and eventually leads to pathological apoptosis, cellular 
resistance and other many metabolic disorders. Along with protein oxidation, lipid peroxidation and glycoxidation will lead to 
oxidation of LDL, followed by pathological apoptosis, dissregulation of oxidant- antioxidant mechanism, which results into 
cellular resistance & numerous pathological conditions. 


From the incidences of CoVlD-19, anyone would be able to identify the co-morbidities, encountered in the association of case 
fatality & susceptibility to the viral infections. The incidences suggest that, patients with high Oxidative stress, that means who 
are the victims of several metabolic, neuro-degenerative & auto immune disorders are commonly affected by the SARS-CoV-2 
and exhibits a drastic result. So, if one tries to find out the underlying cause of CoVlD-19 outbreak, that is not the SARS-CoV-2; 
the actual pathology behind this, is ‘Oxidative stress’; SARS-CoV-2 is just a result. 


l-jtoKenoUA facUirs 


Aiitloxi<lant xysteiii dysruiictioii 


Kiid<>geiiou.<> factor** 


.SiiKjkc. Pollution. 
Viruses. AJlei^gens. 
Heavy Met;it<, Onm* 
Exposu re to Radiation 


OXIUATIV15 STKKiiS 


Rej^uhir rneUtholisin. 
Over- exertion. Obesity 
.■Viito-immune readion 
Indammation, ROS, RNS 




' DNA daraaftr 

8 - OHdG 
8 -Nitroguaninc 


Lipid Peroxidation 

M alondialdehyde 
Isoprostane 


Protein Oxidation 


Protein carbonyl 
nitrotyrosine 



0 .xidatjvie damage to 
laiminal surface of 
Vasdilar will 


I 

Disrcgulation in the 
UlHqniti n- 

Activation of NK-KB_ 


G iycooxidatlon 

Advanced Gtycation 
End Products^ (AGEP) 


Vascular Pcrmcabilityf 
Arterial stiffness ♦ 
VuHiilar dilatation ^ 


Damage of Hpopn»tcin 
Foriiialiofi of I.ipn1- 
Peroxide, platelet 
Aggregation. Activation 
Of Macrophage?* 


Oxidi/tng 



DeereaNc philological 
A|>0|>UNvis 

Accumulation of mivs tokled 
Proteins 


Plaque formation 
(iiernixUlractivie effeii 
DNA repair t 

defiwnc>- Monocyte adhesion 

Inhibition of NO 

^ Endothelial toxicity 

L^i^e increase in un- ^ 

repaired DNA damage Highly reacti\*e Aldehvdc 


1 in inunocomprom isation 
Naiit>-dcgcncrati\T di^sease 


26 S proteasome 


Large incTvase in 
somatic mutations 
& epigenetic 
alterations 


tiicreiased cellular 
apoj>to!<.is 



Proteasome ^ 


Carcinogenesis lmmiin(Mupprc«i«ion, Metabolic Disorder, Cellular Re-sis>*ancc, Increased 

Susceptibility to the infections. HTN, CK1>. ND diseases, AD.I’D. Cancer. 
Autoimmune disorder. End Miaige diseases 


From the above mentioned flowchart, it is easy to identifythe unavoidable pathological relationship between oxidative stress & 
viral susceptibility. Due to our extremely addiction dependent, drug-dependent, over scientific artificial lifestyle, we have 
adopted several attitudes, which results into the formation of oxygen free radicals in a larger amount. It should be kept in mind 
that, microorganisms must require a suitable environment to reside & to infect; they are the natural scavengers, attracted by 
the polluted environment within our body. 

Now, we have to take a short view about the exogenous & endogenous causations of productions of oxidants. 


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Oxidants 


t t 

— Endogenous 

—► Inflammation 
—► Normal diet 
—► Stress 
—► Anxiety 
—► Negative thinking 
^ Autoimmune reactions 


One may encounter from the incidences of CoVlD-19, top affected countries are those who comes either under the category of 
developed countries which means having more artificial life, ingestion of more genetically modified foods, consumption of 
more abusive substances, exposed to more radiations, having most updated medical condition, i.e. over-dependency on drugs, 
e.t.c.; or those countries, which are highly polluted, populated, having over drug-dependency and falls under the category of 
developing countries. Eventually, mostly affected countries by SARS-CoV-2 are those which have higher incidences of metabolic 
disorders [NIDDM, HTN, CAD], psychological disorders, Neuro-degenerative disorder, obesity and several other drug- 
dependent modernized pathologies. Top SARS-CoV-2 affected countries are those which have higher annual income from the 
pharmaceutical industries. 


Highest CoVID-19 Affected Countries 

1000000 
900000 
800000 
700000 
600000 
500000 
400000 
300000 
200000 
100000 
0 


Figure 06 


H Series 1 


BE 


tm 




B.B.a,a,a, 


< C ^ >. v;: 

^ ^ 

Z) Q. 

LT) 


>• C ^ 


E 


U <L) 
«= 

rs i- 
i- Z5 


r3 c V, ^ 


SZ n3 CO "o r3 

^ -g -o c 
ns 


<D 


Co ns i- rg — 

ns— Jz 

Cr: ^ -Fi ns — Qj 

m ^ ^ i::! 


ra '= "D — 

E < 

ra 


rs O ^ rg 




z> 

< 


QJ 




^ O 
^ 


o 


Exogenoas 

Air pollution 

Smoking 

Radiation 

Radio frequency 

Abusive-substances 

Drugs 

Occupational hazards 
Microorganisms 


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Figure 07 


Countries with Higher Drug Abuse with 
addictions 







r?> 





u Sehet 1 


Figure 08 


By comparing Fig. 03 & 04, one can easily understand the unavoidable relationship between CoVlD-19 affected cases and drug- 
dependent lifestyle. Those countries having most advanced modern medical set up, whose population is largely dependent on 
the pharmaceutical agents, which means higher consumption of artificial chemical agents, people of those countries affected by 
CoVlD-19 in a larger extent. Modern medical treatment is concentrating on the effects manifested through the material 
organism, not the cause behind that pathology. Moreover, artificial chemical agents can create more oxidative stress and leads 
to more drastic outcomes. 


By comparing Fig. 03 & 05, one can understand the further relationship between abusive substances abuse & CoVlD-19 
affections. Without considering these actual pathologies, only considering a virus as a causative agent for this deadly pathology 
is just immaterial. 

Apart from these causes, one more important underlying cause is there, which is HLA- system. The persons with deficiencies or 
having over expression in the HLA system are more affected by CoVid-19, as incidences suggest. The irregularity of the HLA 
system is mediated by the above mentioned causes along with some inherited genetic defects. As a whole, the cause of this 
uncontrollable CoVlD-19 will be— 


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Main Cause 

Sub-Causes 

Results 


Pollution 

Lung Injury 


Radiation 

Redox toxicity 


Drug Abuse 

Cardlo-vascular pathology 


Smoking 

Neuro- degenerative diseases 


Alcoholism 

NIDDM 


Stress 

Hypertension 


Anxiety 

Coronary Artery Disease 


Radiation damage 

Dysllpldaemla 

Oxidative stress 

Negative thinking 

Obesity 

Over consumption of medicines 

Atherosclerosis 


Improper treatment strategies 

Hepatic Dysfunction 


Population 

Psychological Disturbances 


Improper waste management 

Auto Immune disorders 


Genetically modified food products 

Depression 


Over use of steroids 

Dissregulation in Oxidant- Antioxidant cycle 


Immuno-suppression 

Dissregulation of RAAS 

Dissregulation of Androgen cycle 
Carcinogenesis 


Cutting trees 

Increased Pollution 


Fire in Amazon 

Redox Damage 

Natural Disasters 

Fire in forests 

Carcinogenesis 


Killing animals 

Damaging natural equilibrium 

Other Oxidative stress related diseases 


HLA- haplotypes 

Increased Susceptibility to infection 


Smoking gene 

Auto immune disorder 

Genetic Causes 

Cancer gene 

More susceptible to Oxidative stress 

Alcoholic gene 

Coellac diseases 

Metabolic disorder 

Cancer 


Clinical Features with Staging: 

Different individual exhibits variety of symptoms & signs with different gradations. Symptoms are of varying characters, 
because of their varieties of affection or rather severity of affection. For the purpose of a successful prescription, one have to 
monitor every findings manifested on the diseased Individual, including their co-morbidities, cause of that co-morbidity, 
duration of the co-morbidity, treatment taken for that particular disease, their food habits, life style, mode of thinking, 
psychological background, occupation, addictions, screen time, choice, preference & e.t.c. Each & every factor is Important for a 
successful prescription, not only for the successful treatment, rather for the prevention also. From the above mentioned points, 
clinician can judge the degree of oxidative stress, severity of the co-morbidities and also he can calculate the complications & 
severity of the present suffering. Here we have outlined some clinical findings, received from various patients of different 
geographical areas suffering from CoVlD-19. 


Stages 

Name of the Stage 


Symptoms 

Characteristic Pathological findings 

Stage-1 

Asymptomatic or Period 

> 

Sneezing 

> ESR 


of Non-severe Symptoms 

> 

Pain in throat 

> Leucocytosis 


[Acute Inflammatory 

> 

Constricted feeling in throat 

> Activated T-cell 


stage] 

> 

Burning in eyes 




> 

Fever 




> 

Hyper sensitivity to the smell 




> 

Conjunctivitis 




> 

Glossitis 




> 

Oppression of chest 




> 

Shortness of breath 




> 

Irritability 




> 

General restlessness 




> 

Dry cough 




> 

Mucous in chest 




> 

Pain in throat 




> 

Pain in Head, mainly in frontal head 




> 

Decreased appetite 




> 

Bitter taste in mouth 




> 

Hyperchlorhydria 




> 

Fearfulness 




> 

Ignorant about their ailment 



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Stage -11 

Period of Severe 
symptoms 

[Stage of Early Chronic 
Inflammation] 

> Shortness of breath 

> Excessive mucous on chest 

> Eever 

> Constricted feeling in throat 

> Myalgia 

> Dyspnoea 

> Loss of appetite 

> Nausea 

> Asomnia 

> Vomiting 

> Burning in abdomen 

> Irritability 

> Palpitation 

> High feverish state 

> Extreme sensitive to the cold 

> Headache 

> Irregular bowel movement 

> Eatigue 

> Palpitation 

> Burning in urethra 

> High smelling urine 

> Proteinuria 

> Haematuria 

> Hepatomegaly 

> Eearfulness 

> State of confusion 

> Peeling of loneliness 

> Escapist mentality 

> Porgetfulness 

> Tremor 

> Lymphocytopenia 

> lL-6 increased 

> Cytokine storm 

> Diffuse Patchy spots in lung field 

Stage - 
ill 

Period of extremely 
severe condition 

[Stage of Chronic 
inflammation] 

> Asomnia 

> Metallic taste 

> Eever 

> Extreme prostration 

> Palpitation 

> Pain in chest 

> Dyspnoea 

> Extreme prostration 

> Oppression in chest 

> Constriction in chest 

> Heaviness of chest 

> Nausea 

> Vomiting 

> Diarrhoea 

> Gastro-lntestinal Bleeding 

> Bilious vomiting 

> Loss of appetite 

> Suppressed urination 

> Hallitosis 

> Haematuria 

> Confused 

> Highly anxious 

> Sensitive to slightest change of 
surroundings 

> Pear of death 

> Pear of loneliness 

> Panicked 

> Swelling 

> Haemorrhagic spots in skin 

> Anaemic condition 

> Bromidrosis 

> Delirium 

> Panicked 

> Pibrotic changes is seen in the lung 
shadow 

> Ground-Glass appearance in the 

Lung Shadow 

> Lymphocytopenia 


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Indicated Medicines according to the Stage: __ 


Stages 

Indicated Medicine 

Stage-1 

> Aconitum napellus 

> Belladona 

> Eupatorium perfoliatum 

> Gelsemium 

> Bryonia alba 

Stage- II 

> Gelsemium 

> Bryonia alba 

> Hepar sulphuricum 

> Sulphur 

Stage- III 

> Mercurius solubilis 

> Phosphorus 

> Arsenicum album 

> Chininum arsenicosum 


Modus Operandi of Some Indicated Homoeopathic Medicine: 

At first, the modus operandi of Homoeopathic medicine is outlined through a flow chart. Homoeopathic medicines are rich in 
energy and less in materialistic quantity, which is why the chances of toxicity is minimum. The medicines are able to create 
similar pathway by acting through the nervous system, by conducting the impulse by means of nervous signalling. The signal 
first creates similar pathological condition by involving similar pathway but in the higher intensity. From the flow chart of the 
medicinal actions of the specific medicines of CoVlD-19, one would be able to identify that; at the different levels of the natural 
pathological pathway, i.e. the stages of the disease several disturbances appeared naturally as a byproduct of the disease 
preventing mechanism of the body; the indicated medicine specific for the particular stage, neutralizes those effects by creating 
a similar medicinal pathway. The mechanism is not only harmless, but beneficial also. But one should keep in mind that, the 
proper indicated medicine must be identified in a proper manner, without any prejudice. 


Mcxlicine 


Nca-c^ currier iiKxlKirul 


1 


ihctHnly nuiiiife>icil 

by oi cticmical imNiUncc hciVrcen ^ 
palhotofy indticc<l«rxl ncutratirin^ cbcmicolt-. 


1 


If the elicniical itubalancc C4iuscs 
ReJik'tHm in nc«ir.ilirin]c/ 
ash-influmnuiU>r> 

chemieoK in oaicr ioe\iin^uish 

•the phentHiicnii 

i 

HivnocopatlMi.’ McJiciiic pnidiKCv 
pathii^ncsis similar in the ruitiiral dhici^c: 
mcdtcincH create pjihof cikm% 
viiniUr lo itic puilt<>tcncM\4it nalufal diMra>c 

B»h.I> jivo Mmilar 

gi\«n tn cau.* uf atlurul dt4cu%e. 

But in u hiphcr Kitcnsitx. 
uf ciinjoiiM p(itho]icnc>t> itf 
aaltral ptilluiaaix and mcdicincx. 

A\ iTutcrial tiiod ix not there. m> there i»> 
m> chetnee <it ntnlcriiil m'crkuJ 
iHonrocopathac Aggravation i 


Clicniicu) imbaloiKe couvev 
inertave in the anikKims of 
chenucal vuhMunces than the 
loiuired amount. 
4Medivin.il aggravutioni 


Wait for soiite lime to naitialt/e 
the na^tkesui) m^rdove h> the Ixhiy 
nacurallv or udiiiinivtcr anltilobrv 


Biid) !ixv neulralt/cx itul iinhalanct.' 
naturally, by itself b> ucltvaling 
aAii-influitinuiUtry systan. .minKidani vy stems, 
and («her hoinoeosUtic syNlenis 
as lb nuluraJ pbcnonx'tKKt 


Removol of the rulural disease by 
nic;sts of removal of the chemiL'al 
imbalance pnvduccO by ihe 
•atural dneo^ by the body natunilly 


Chcnucal iitihulancc produced 
by the incdicttul vvibMance 
remains . 


Than irnhsUancc viill pass of 
autonuticily. nhen the 
patUtulur pcrx^l of action 
of medicine passed. 


Modus operandi of Homoeopathy [In General] 


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Treatment: 



Modus operand! of ffomoeopathic Medicines in CoVlD-19 


-nf Ci^VI 1^-19 


- l*rc%'ciilLvc 

NmIHIiOws? 

► Klop. Hi'iTirikBi'ift 

h pliyatr-ft] oicrdfiC 

^Koorfscric#! in Vit- U 5 
rLrfn in Vit C 

■ Ci^rlk: in is riuh in ^Iphur 

OunL^in Ln^ AJliun) 

' Pru-ptfir Lrc.'silrru'iil urCu-iiiorbUJiLii3y- 
^Avtnd. iic'^alive tlkirLkin-j* 

► Avmd. 

► MaiifijikSEiiiyiil i>rsij-^as 
^Atjunilum nupullui; o-tl csqxjsurici 

' hfainisthi CBuLti IciL.i & vxLiJ 

•-Avoid Ii^^livo [-[ 11:311011 C.l]l 3 pit« 

Av^jifl TflciSfil In-i-i 
« ^crc^sn Ijmkc 

■■ Hc-nciin^ ftf honVifi 

^ Mninl^iiim^ nf flkKUindn^ 

IJnij^nsc nbntkld Hr minimi^^rcl 
Kngitgu youcT^ir-kn pnidiictiv^ ivxiTi^ 
' KlAnttntinn of LT<frij; iriArirJfltory 

^ h.irming nnim^lR 


C.^rallvc 

‘Trripci' Mi.itrilif^i.11? iTnoci 
^ HInp Hn-koltltip, 

Hlnpfllcnhol 

*■ AHHXln-RlbpHyKkc^l cwri^KC 
^ Kood^ rieth -in Vil- II:-; 

>■ l'■cwds• nir-h in Vit C: 

^ G^Tliu (i!K il Ia ritili in Sulphur 
Cuiilairting AJIiciin^ 

Prop^fr txtJulmmE. urCu-inurb-itlkLltsi 
■' Awi-J nuKsiLivL' Hi inking 

•■ Awid S INra; 

■- Mf’LiiaKOiiiPiiL caf SirL^ea- 
■■ fiid.U.iiL4f<l i$u^aLab■]c^ 

fur Ukkj CTsmcf, vs'itik cviudid^rin^ 
c:o-iiioi-bdd 

" MftiiUflin hyfiiciifl !nlr 

- Ayrkid kkOf’^lK'C: prrn-i-i-ot5nki thrift Apllko n-f 
dcjftrcc nf Irkith) 

■- A-wi-d radlflHon 

- MfiinlJkiTi pTnpf:r cwygcnnlinn 
“ Kltiid ■cLrrtT'C^lytT: h.ilnnr^ 

shcnilcl hr m-tin-Linnod 
^ liqiolAtinn 

‘ tfingftr A JTiirmwir 
'- We ll venlLliklnl r£>r>m 


■ f^nlllat-kvc- 

*" c^jsyisenatioiii 
-H K-H Halniioo 
Am flih. / 
Mcrc-s^l- 
t'rovrinlion of 
*■ ilyaliironan 
fcirm Jli(?n 
Vil- ti:i Sc C 

OLhe-r 
pvii: y-iblu 
^ iiitja'a-urt:^i 

in prtfviuutf 
t:urab.iv^ p-arL 
leCaldMCart. 

tvwvn-fc 


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Clinical Trial with Homoeopathic medications: 

Clinical trial is possible in a minimum number of the patients, who are exposed to CoVlD-19, who have co-morbidities and also 
as a prophylactic. As a prophylaxis we have taken a group of volunteers, which are divided into three groups: one is on placebo, 
second is on Arsenicum album, irrespective of their characteristics, and third group is on the indicated medicine as per their 
genetic make up & co-morbidities. Result are: group: Flu like symptom in 16 % cases, 

2nd group: Flu like symptoms in 5% cases 

3rd group: Absence of any flu like symptoms 


Prophylaxis with Homoeopathy in 3rd 

group 


HSulphur 
■ Arsen icunn album 
BGolscmium 

BAconiunnapelkis 


Figure-09 

Flu like symptoms & Homoeopathy 

H Aconite 
il Bella don a 
UGelsemium 
H Sulphur 
H Arsenicum alhum 
■ EryoniaialbaB 
H Phosphorus 


Figure 10 

Along with the clinical trials, there are number of cases which are treated by the homoeopathic medicines successfully. 
Indicated Homoeopathic medicines have proved its efficacy in all the stages of the CoVlD-19 in a very clear manner. There is 
not a single case which turns fatal during the treatment with indicated Homoeopathic medicines, it is not clear to us, why Govt, 
of India promoting this system of medicine as a immune booster, particularly when there are several evidences regarding 
successful management with the Homoeopathic medications. 

We have noticed that, there are variations in the symptomatologies on different geographical conditions. As the virus 
is continuously modifying according to the geographical condition and people of different areas are of different 
characteristics, the manifestations are notably different. For that reason, administering an arbitrary Genus 
epidemicus is not at all desirable; this must be not beneficial for the mankind and for the Homoeopathic system both. 




Conclusion: 

From the above discussion one can understand all the facts, 
rumors & truths of CoVlD-19 & several other pathological 
conditions. Faults & fallacies are there within our 


psychological pattern, our life style, our understanding and 
above all within our treatment procedure. We are used to 
consider our patients as instruments and in order to correct 
the instrumental abnormality; we act like an engineer, 


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without considering body’s own protective functions. CoVlD- 
19 is not at all a fatal disease, without the predisposing 
condition. This is the gift of our most learned scientific 
community, who thought themselves as the creator. 
Manipulation with the nature is directly proportional to this 
ever growing disease pillars. If we have any intention to live 
for a longer period in the nature, we have to manage our 
oxidative stress & other internal impurities naturally. We 
have to live close to the nature by obeying natural rules. 
More we try to manipulate the nature; nature will remove us 
by considering us as a foreign body or diseased substance. 
Infections are just the result, not the cause. So, it is better to 
stop blaming microorganisms as a disease producing 
element. 

"Nature is the best Physician" — Hippocrates 
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